Neoplasms, Second Primary
Research News and Information

Sunday, November 22, 2009

p73 G4C14-to-A4T14 polymorphism and risk of second primary malignancy after index squamous cell carcinoma of head and neck.

29 Nov 2009 P73 plays an important role in modulating cell-cycle control, inducing apoptosis, and inhibiting cell growth. A novel noncoding p73 G4C14-to-A4T14 exon 2 polymorphism was associated with risk of squamous cell carcinoma of the head and neck (SCCHN). ... Read more...

Risk of thyroid cancer in survivors of childhood cancer: results from the British Childhood Cancer Survivor Study.

13 Nov 2009 Second primary neoplasms (SPNs) are a recognised late effect of treatment for childhood cancer. Thyroid SPNs can develop after exposure to low-dose radiation, due to the radio-sensitivity of the thyroid gland. The British Childhood Cancer Survivor ... Read more...

Early development of acute myeloid leukemia following treatment of osteosarcoma: a case report and review of the literature.

29 Sep 2009 We report a case of treatment-related acute myeloid leukemia (t-AML) in a 16-year-old male following treatment for osteosarcoma (OS). He had been treated with a protocol comprising neoadjuvant chemotherapy, definitive surgery with wide excision and ... Read more...

Latest indexed articles for 'Neoplasms, Second Primary'

These are the very latest articles for this heading:

• p73 G4C14-to-A4T14 polymorphism and risk of second primary malignancy after index squamous cell carcinoma of head and neck. 29 Nov 2009
• Risk of thyroid cancer in survivors of childhood cancer: results from the British Childhood Cancer Survivor Study. 13 Nov 2009
• Second primary cancers in survivors of childhood cancer. 29 Oct 2009
• Communication during breast cancer treatment. 21 Oct 2009
• Early development of acute myeloid leukemia following treatment of osteosarcoma: a case report and review of the literature. 29 Sep 2009
• Editorial comment. 29 Sep 2009
• The predictive value of incidental PET/CT findings suspicious for breast cancer in women with non-breast malignancies. 29 Sep 2009
• TNM stage is the most important determinant of survival in metachronous lung cancer. 29 Sep 2009
• Secondary breast cancer: a 5-year population-based study with review of the literature. 29 Sep 2009
• Risks of radiation therapy in patients with neurofibromatosis. 29 Sep 2009
• Non-Hodgkin lymphoma following temozolomide. 29 Sep 2009
• Granuloma annulare heralding angioimmunoblastic T-cell lymphoma in a patient with a history of epstein-barr virus-associated B-cell lymphoma. 19 Sep 2009
• Bladder cancer in cancer patients: population-based estimates from a large Swedish study. 13 Sep 2009
• Secondary sarcomas after radiotherapy for breast cancer: sustained risk and poor survival. 13 Sep 2009
• [Multiple primary neoplasms - coincidence or tumor syndrom?] 7 Sep 2009
• [Meaning of incidence of extrapancreatic neoplasms in patients with intraductal papillary mucinous neoplasms of pancreas] 30 Aug 2009
• [Extrapancreatic tumors in intraductal papillary mucinous neoplasm of the pancreas] 30 Aug 2009
• Fine-needle aspiration of breast carcinoma metastatic to follicular variant of papillary thyroid carcinoma. 30 Aug 2009
• Local recurrences and second primary tumors from squamous cell carcinoma of the oral cavity: a retrospective analytic study of 500 patients. 30 Aug 2009
• Late effects of treatment for wilms tumor. 30 Aug 2009

See a longer list of these articles.

Technical information about 'Neoplasms, Second Primary'

Definition: Abnormal growths of tissue that follow a previous neoplasm but are not metastases of the latter. The second neoplasm may have the same or different histological type and can occur in the same or different organs as the previous neoplasm but in all cases arises from an independent oncogenic event. The development of the second neoplasm may or may not be related to the treatment for the previous neoplasm since genetic risk or predisposing factors may actually be the cause.

Descriptor UI: D016609

Alternative terms: Neoplasms, Second Primary; Neoplasm, Second Primary; Second Primary Neoplasm; Metachronous Second Primary Neoplasms; Neoplasms, Metachronous; Second Primary Neoplasms, Metachronous; Second Malignancy; Malignancies, Second; Malignancy, Second; Second Malignancies; Second Neoplasm; Neoplasm, Second; Neoplasms, Second; Second Neoplasms; Second Primary Neoplasms; Metachronous Neoplasms; Metachronous Neoplasm; Neoplasm, Metachronous; Neoplasms, Metachronous Second Primary; Neoplasms, Therapy-Associated; Neoplasm, Therapy-Associated; Neoplasms, Therapy Associated; Therapy-Associated Neoplasm; Neoplasms, Treatment-Associated; Neoplasm, Treatment-Associated; Neoplasms, Treatment Associated; Treatment-Associated Neoplasm; Neoplasms, Treatment-Related; Neoplasm, Treatment-Related; Neoplasms, Treatment Related; Treatment-Related Neoplasm; Therapy-Related Neoplasms; Therapy Related Neoplasms; Treatment-Associated Neoplasms; Treatment Associated Neoplasms; Treatment-Related Neoplasms; Treatment Related Neoplasms; Neoplasms, Therapy-Related; Neoplasm, Therapy-Related; Neoplasms, Therapy Related; Therapy-Related Neoplasm; Therapy-Associated Neoplasms; Therapy Associated Neoplasms; Therapy-Associated Cancer; Cancer, Therapy-Associated; Cancers, Therapy-Associated; Therapy Associated Cancer; Therapy-Associated Cancers; Therapy-Related Cancer; Cancer, Therapy-Related; Cancers, Therapy-Related; Therapy Related Cancer; Therapy-Related Cancers; Treatment-Related Cancer; Cancer, Treatment-Related; Cancers, Treatment-Related; Treatment Related Cancer; Treatment-Related Cancers; Treatment-Associated Cancer; Cancer, Treatment-Associated; Cancers, Treatment-Associated; Treatment Associated Cancer; Treatment-Associated Cancers; Cancer, Second Primary; Cancers, Second Primary; Second Primary Cancer; Second Primary Cancers; Second Cancer; Cancer, Second; Cancers, Second; Second Cancers;

Related Mesh Headings: Neoplasms, Multiple Primary;

Allowable Qualifiers: blood; blood supply; cerebrospinal fluid; chemically induced; classification; complications; congenital; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; secondary; secretion; surgery; therapy; ultrastructure; urine; veterinary; ultrasonography; chemistry; virology;

Tree Number: C04.692;

History Note: 92

Technical Notes: a 2d or more neopl of same or different histol type at same or different sites: do not confuse with NEOPLASMS, MULTIPLE PRIMARY (see note there); often follows ther (note X refs); IM; coord with each specific histol type (IM) & each precoord organ/neopl term (IM); do not use /compl with specific multiple neopl terms to show multiplicity; Manual 24.4.1.7; differentiate from NEOPLASM METASTASIS (Manual 24.4.1.3+) & NEOPLASM RECURRENCE, LOCAL: Manual 24.4.1.5