Neoplastic Stem Cells
Research News and Information

Sunday, November 22, 2009

Tubulin targets in the pathobiology and therapy of glioblastoma multiforme. I. Class III beta-tubulin.

29 Nov 2009 Glioblastoma multiforme (GBM) is the most common and deadliest form of primary brain cancer in adults. Despite advances in molecular biology and genetics of gliomas currently there is no effective treatment or promising molecularly targeted ... Read more...

Radiation response of cancer stem-like cells from established human cell lines after sorting for surface markers.

13 Nov 2009 PURPOSE: A subpopulation of cancer stem-like cells (CSLC) is hypothesized to exist in different cancer cell lines and to mediate radioresistance in solid tumors. METHODS AND MATERIALS: Cells were stained for CSLC markers and sorted ... Read more...

CD44-positive cells are responsible for gemcitabine resistance in pancreatic cancer cells.

13 Nov 2009 Accumulating evidence suggests that tumors are composed of a heterogeneous cell population with a small subset of cancer stem cells (CSCs) that sustain tumor formation and growth. Recently, there have been efforts to explain drug resistance of ... Read more...

Latest indexed articles for 'Neoplastic Stem Cells'

These are the very latest articles for this heading:

• Tubulin targets in the pathobiology and therapy of glioblastoma multiforme. I. Class III beta-tubulin. 29 Nov 2009
• Radiation response of cancer stem-like cells from established human cell lines after sorting for surface markers. 13 Nov 2009
• CD44-positive cells are responsible for gemcitabine resistance in pancreatic cancer cells. 13 Nov 2009
• Enhanced MDR1 expression and chemoresistance of cancer stem cells derived from glioblastoma. 30 Oct 2009
• Human prostate-infiltrating CD8+ T lymphocytes are oligoclonal and PD-1+. 30 Oct 2009
• In vitro propagation and characterization of neoplastic stem/progenitor-like cells from human prostate cancer tissue. 30 Oct 2009
• High-throughput screening finds potential killer of cancer stem cells. 12 Oct 2009
• Modulation of invasive properties of CD133+ glioblastoma stem cells: a role for MT1-MMP in bioactive lysophospholipid signaling. 29 Sep 2009
• Tumour-initiating cells: challenges and opportunities for anticancer drug discovery. 29 Sep 2009
• Prognostic significance of the cancer stem cell markers CD133, CD44, and CD166 in colorectal cancer. 29 Sep 2009
• Side population cells have the characteristics of cancer stem-like cells/cancer-initiating cells in bone sarcomas. 27 Sep 2009
• The tumor suppressor p53 regulates polarity of self-renewing divisions in mammary stem cells. 16 Sep 2009
• p53: a new kingpin in the stem cell arena. 16 Sep 2009
• Eradication of chronic myeloid leukemia stem cells: a novel mathematical model predicts no therapeutic benefit of adding G-CSF to imatinib. 9 Sep 2009
• Highly tumorigenic lung cancer CD133+ cells display stem-like features and are spared by cisplatin treatment. 8 Sep 2009
• A luminal epithelial stem cell that is a cell of origin for prostate cancer. 7 Sep 2009
• Glioma tumor stem-like cells promote tumor angiogenesis and vasculogenesis via vascular endothelial growth factor and stromal-derived factor 1. 6 Sep 2009
• Cancer stem cells: mirage or reality? 2 Sep 2009
• Heterogeneity in cancer: cancer stem cells versus clonal evolution. 2 Sep 2009
• Cancer stem cell marker CD133+ tumour cells and clinical outcome in rectal cancer. 30 Aug 2009

See a longer list of these articles.

Technical information about 'Neoplastic Stem Cells'

Definition: Colony-forming cells which give rise to NEOPLASMS. They have properties similar to normal stem cells, i.e., high proliferative and self-renewal capacities.

Descriptor UI: D014411

Alternative terms: Neoplastic Stem Cells; Cell, Neoplastic Stem; Cells, Neoplastic Stem; Neoplastic Stem Cell; Stem Cell, Neoplastic; Neoplastic Colony-Forming Units; Neoplastic Colony Forming Units; Tumor Stem Cells; Cell, Tumor Stem; Cells, Tumor Stem; Stem Cell, Tumor; Stem Cells, Tumor; Tumor Stem Cell; Colony-Forming Units, Neoplastic; Colony Forming Units, Neoplastic; Colony-Forming Unit, Neoplastic; Neoplastic Colony-Forming Unit; Unit, Neoplastic Colony-Forming; Units, Neoplastic Colony-Forming; Stem Cells, Neoplastic; Cancer Stem Cells; Cancer Stem Cell; Cell, Cancer Stem; Cells, Cancer Stem; Stem Cell, Cancer; Stem Cells, Cancer;

Allowable Qualifiers: classification; cytology; drug effects; enzymology; immunology; metabolism; microbiology; parasitology; pathology; physiology; radiation effects; radiography; radionuclide imaging; secretion; transplantation; ultrastructure; ultrasonography; chemistry; virology;

Tree Number: A11.872.650;

History Note: 2008 (1984)