Nephrosclerosis - Metabolism
Research News and Information

Monday, November 23, 2009

Astragalus mongholicus ameliorates renal fibrosis by modulating HGF and TGF-beta in rats with unilateral ureteral obstruction.

29 Apr 2009 Astragalus mongholicus (AM) derived from the dry root of Astragalus membranaceus Bge. var. mongolicus (Bge.) Hsiao is a widely used traditional Chinese medicine. The present study investigated the potential role of AM on renal fibrosis on a rat ... Read more...

Parenchymal injury in remnant-kidney model may be linked to apoptosis of renal cells mediated by nitric oxide.

30 Aug 2008 BACKGROUND: The importance of apoptotic cell death in the pathogenesis of progressive renal sclerosis has been well established. While activity of vasorelaxant nitric oxide is conceivable in the remnant hyperfiltrating kidney and nitric oxide has ... Read more...

Fasudil, a Rho-kinase inhibitor, reverses L-NAME exacerbated severe nephrosclerosis in spontaneously hypertensive rats.

30 Aug 2008 BACKGROUND: In this study, we tested the hypothesis that long-term Rho-kinase inhibition would reverse nitro-L-arginine methyl ester-exacerbated nephrosclerosis in spontaneously hypertensive rats and attempted to elucidate the mechanism involved. ... Read more...

Latest indexed articles for 'Nephrosclerosis - Metabolism'

These are the very latest articles for this heading:

• Astragalus mongholicus ameliorates renal fibrosis by modulating HGF and TGF-beta in rats with unilateral ureteral obstruction. 29 Apr 2009
• Parenchymal injury in remnant-kidney model may be linked to apoptosis of renal cells mediated by nitric oxide. 30 Aug 2008
• Fasudil, a Rho-kinase inhibitor, reverses L-NAME exacerbated severe nephrosclerosis in spontaneously hypertensive rats. 30 Aug 2008
• The aggravating mechanisms of aldosterone on kidney fibrosis. 9 Jun 2008
• Hypertension induces somatic cellular senescence in rats and humans by induction of cell cycle inhibitor p16INK4a. 24 May 2008
• CRBP-I in the renal tubulointerstitial compartment of healthy rats and rats with renal fibrosis. 23 May 2008
• Calcium-mediated parathyroid hormone release changes in patients treated with the calcimimetic agent cinacalcet. 17 Apr 2008
• Progressive kidney disease in three sisters with elevated lipoprotein(a). 14 Jan 2008
• Mutations in PLCE1 are a major cause of isolated diffuse mesangial sclerosis (IDMS). 6 Dec 2007
• Combination therapy with telmisartan and spironolactone alleviates L-NAME exacerbated nephrosclerosis with an increase in PPAR-gamma and decrease in TGF-beta(1). 30 Aug 2007
• Age trends of renal arteriolar hyalinization explored with the aid of serial sections. 27 Jan 2007
• [Expression of p27 in rat kidney with unilateral ureteral obstruction and the therapeutic effect of enalapril] 29 Sep 2006
• [P21 expression in renal interstitial fibrosis and regulative effect of enalapril] 29 Sep 2006
• Renal vascular sclerosis is associated with inherited thrombophilias. 5 Jun 2006
• Angiotensin II formation in the kidney and nephrosclerosis in Ren-2 hypertensive rats. 5 Mar 2006
• [Effect of perindopril on renal interstitial fibrosis of hypertension in rats] 30 Jan 2004
• [Expression of p27 in renal interstital fibrosis in rats induced by unilateral ureteral obstruction] 30 Jan 2004
• Lipid profile before and after renal transplantation--a longitudinal study. 29 Apr 2003
• [The pathology of nephrosclerosis and hypertension] 29 Nov 2002
• Prostacyclin-deficient mice develop ischemic renal disorders, including nephrosclerosis and renal infarction. 27 Oct 2002

See a longer list of these articles.

Technical information about 'Nephrosclerosis'

Definition: Hardening of the KIDNEY due to infiltration by fibrous connective tissue (FIBROSIS), usually caused by renovascular diseases or chronic HYPERTENSION. Nephrosclerosis leads to renal ISCHEMIA.

Descriptor UI: D009400

Alternative terms: Nephrosclerosis; Nephroscleroses;

Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; congenital; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; urine; veterinary; ultrasonography; virology;

Tree Number: C12.777.419.610; C13.351.968.419.610;