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Nerve Fibers, Myelinated - Ultrastructure
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Definition of 'Nerve Fibers, Myelinated'

A class of nerve fibers as defined by their structure, specifically the nerve sheath arrangement. The AXONS of the myelinated nerve fibers are completely encased in a MYELIN SHEATH. They are fibers of relatively large and varied diameters. Their NEURAL CONDUCTION rates are faster than those of the unmyelinated nerve fibers (NERVE FIBERS, UNMYELINATED). Myelinated nerve fibers are present in somatic and autonomic nerves.

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Sunday, November 22, 2009

Conduction block and glial injury induced in developing central white matter by glycine, GABA, noradrenalin, or nicotine, studied in isolated neonatal rat optic nerve.

13 Aug 2009 The damaging effects of excessive glutamate receptor activation have been highlighted recently during injury in developing central white matter. We have examined the effects of acute exposure to four other neurotransmitters that have known actions ... Read more...


GDNF-enhanced axonal regeneration and myelination following spinal cord injury is mediated by primary effects on neurons.

13 Aug 2009 We previously demonstrated that coadministration of glial cell line-derived neurotrophic factor (GDNF) with grafts of Schwann cells (SCs) enhanced axonal regeneration and remyelination following spinal cord injury (SCI). However, the cellular target ... Read more...


Beta1 integrins are required for normal CNS myelination and promote AKT-dependent myelin outgrowth.

30 Jul 2009 Oligodendrocytes in the central nervous system (CNS) produce myelin sheaths that insulate axons to ensure fast propagation of action potentials. beta1 integrins regulate the myelination of peripheral nerves, but their function during the myelination ... Read more...

 

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Technical information about 'Nerve Fibers, Myelinated'

Definition: A class of nerve fibers as defined by their structure, specifically the nerve sheath arrangement. The AXONS of the myelinated nerve fibers are completely encased in a MYELIN SHEATH. They are fibers of relatively large and varied diameters. Their NEURAL CONDUCTION rates are faster than those of the unmyelinated nerve fibers (NERVE FIBERS, UNMYELINATED). Myelinated nerve fibers are present in somatic and autonomic nerves.

Descriptor UI: D009413

Alternative terms: Nerve Fibers, Myelinated; Fiber, Myelinated Nerve; Fibers, Myelinated Nerve; Myelinated Nerve Fiber; Myelinated Nerve Fibers; Nerve Fiber, Myelinated; B Fibers; B Fiber; Fiber, B; Fibers, B; A Fibers; A Fiber; Fiber, A; Fibers, A;

Allowable Qualifiers: classification; drug effects; enzymology; immunology; metabolism; microbiology; parasitology; pathology; physiology; radiation effects; radiography; radionuclide imaging; secretion; transplantation; ultrastructure; ultrasonography; chemistry; virology;

Tree Number: A08.663.542.512; A11.671.514;

History Note: 1974 (1972); for B FIBERS use AUTONOMIC FIBERS, PREGANGLIONIC 1976-2002

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