Nerve Growth Factors - Metabolism
Research News and Information

Saturday, November 21, 2009

Disruption of the axon initial segment cytoskeleton is a new mechanism for neuronal injury.

19 Oct 2009 Many factors contribute to nervous system dysfunction and failure to regenerate after injury or disease. Here, we describe a previously unrecognized mechanism for nervous system injury. We show that neuronal injury causes rapid, irreversible, and ... Read more...

Fates of neurotrophins after retrograde axonal transport: phosphorylation of p75NTR is a sorting signal for delayed degradation.

24 Aug 2009 Neurotrophins can mediate survival or death of neurons. Opposing functions of neurotrophins are based on binding of these ligands to two distinct types of receptors: trk receptors and p75NTR. Previous work showed that target-derived NGF induces cell ... Read more...

Changes in aqueous vascular endothelial growth factor and pigment epithelium-derived factor after ranibizumab alone or combined with verteporfin for exudative age-related macular degeneration.

9 Aug 2009 PURPOSE: To investigate changes in aqueous vascular endothelial growth factor (VEGF) and pigment epithelium-derived factor (PEDF) in choroidal neovascularization (CNV) secondary to age-related macular degeneration (AMD) after ranibizumab (Lucentis; ... Read more...

Latest indexed articles for 'Nerve Growth Factors - Metabolism'

These are the very latest articles for this heading:

• Disruption of the axon initial segment cytoskeleton is a new mechanism for neuronal injury. 19 Oct 2009
• Fates of neurotrophins after retrograde axonal transport: phosphorylation of p75NTR is a sorting signal for delayed degradation. 24 Aug 2009
• Changes in aqueous vascular endothelial growth factor and pigment epithelium-derived factor after ranibizumab alone or combined with verteporfin for exudative age-related macular degeneration. 9 Aug 2009
• The stochastic search dynamics of interneuron migration. 3 Aug 2009
• Prognostic significance of neuron-associated protein expression in non-muscle-invasive urothelial bladder cancer. 30 Jul 2009
• Integrin acts upstream of netrin signaling to regulate formation of the anchor cell's invasive membrane in C. elegans. 30 Jul 2009
• Physical activity as an exogenous risk factor in motor neuron disease (MND): a review of the evidence. 30 Jul 2009
• Triggers of apoptosis in the immature brain. 30 Jul 2009
• Amyloid beta-induced nerve growth factor dysmetabolism in Alzheimer disease. 30 Jul 2009
• Growth factor-expressing human neural progenitor cell grafts protect motor neurons but do not ameliorate motor performance and survival in ALS mice. 29 Jul 2009
• Nuclear receptor co-repressor is required to maintain proliferation of normal intestinal epithelial cells in culture and down-modulates the expression of pigment epithelium-derived factor. 14 Jul 2009
• Netrin-DCC, Robo-Slit, and heparan sulfate proteoglycans coordinate lateral positioning of longitudinal dopaminergic diencephalospinal axons. 13 Jul 2009
• Proteasomal inhibition alters the trafficking of the neurotrophin receptor TrkA. 12 Jul 2009
• Bergmann glial S100B activates myo-inositol monophosphatase 1 and Co-localizes to purkinje cell vacuoles in SCA1 transgenic mice. 9 Jul 2009
• Crucial role of the local micro-environment in fate decision of neonatal rat NG2 progenitors. 7 Jul 2009
• Small molecules bound to unique sites in the target protein binding cleft of calcium-bound S100B as characterized by nuclear magnetic resonance and X-ray crystallography. 5 Jul 2009
• Brain derived neurotrophic factor and neurotrophin-4 employ different intracellular pathways to modulate norepinephrine uptake and release in rat hypothalamus. 30 Jun 2009
• Changes of aqueous vascular endothelial growth factor and pigment epithelium-derived factor following intravitreal bevacizumab for macular oedema secondary to branch retinal vein occlusion. 29 Jun 2009
• Pigment epithelium-derived factor contributes to insulin resistance in obesity. 29 Jun 2009
• Effects of light exposure and use of intraocular lens on retinal pigment epithelial cells in vitro. 29 Jun 2009

See a longer list of these articles.

Technical information about 'Nerve Growth Factors'

Definition: Factors which enhance the growth potentialities of sensory and sympathetic nerve cells.

Registry Number: 0

Descriptor UI: D009414

Alternative terms: Nerve Growth Factors; Factors, Nerve Growth; Neurotrophic Factors; Factors, Neurotrophic; Neurotrophic Proteins; Neurotrophins; Neuronotrophic Factors; Factors, Neuronotrophic; Neurotrophic Protein; Growth-Associated Proteins, Neuronal; Growth Associated Proteins, Neuronal; Proteins, Neuronal Growth-Associated; Neuronal Growth-Associated Proteins; Neuronal Growth Associated Proteins; Neurite Outgrowth Factors; Factors, Neurite Outgrowth; Outgrowth Factors, Neurite;

Related Mesh Headings: Receptors, Nerve Growth Factor;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; agonists;

Tree Number: D12.644.276.860; D12.776.467.860; D12.776.641.600; D23.529.850;

History Note: 1980; use NERVE GROWTH FACTOR 1966-1979; for NEUROTROPHIC PROTEIN use NERVE GROWTH FACTORS (NM) 1978-1999

Technical Notes: NERVE GROWTH FACTOR is also available