Nerve Growth Factors
Research News and Information

Saturday, November 21, 2009

Disruption of the axon initial segment cytoskeleton is a new mechanism for neuronal injury.

19 Oct 2009 Many factors contribute to nervous system dysfunction and failure to regenerate after injury or disease. Here, we describe a previously unrecognized mechanism for nervous system injury. We show that neuronal injury causes rapid, irreversible, and ... Read more...

A neurotrophic rationale for the therapy of neurodegenerative disorders.

29 Sep 2009 The concept and rationale for neuroprotection are presented. Several examples of small molecule neurotrophic agents with favourable drug-like and pharmacological properties are shown. Compound efficacy in acute neurodegenerative models (optic nerve ... Read more...

Diagnostic value of S100B and neuron-specific enolase in mild pediatric traumatic brain injury.

29 Sep 2009 OBJECT: During recent years, several biomarkers have been introduced for use in the diagnosis of traumatic brain injury (TBI). The primary objective of this investigation was to determine if S100B (or S100 calcium-binding protein B) and ... Read more...

Latest indexed articles for 'Nerve Growth Factors'

These are the very latest articles for this heading:

• Disruption of the axon initial segment cytoskeleton is a new mechanism for neuronal injury. 19 Oct 2009
• A neurotrophic rationale for the therapy of neurodegenerative disorders. 29 Sep 2009
• Diagnostic value of S100B and neuron-specific enolase in mild pediatric traumatic brain injury. 29 Sep 2009
• Relationship of serum S100B levels and intracranial injury in children with closed head trauma. 26 Sep 2009
• Neonatal S100B protein levels after prenatal exposure to selective serotonin reuptake inhibitors. 26 Sep 2009
• Heterozygous NTF4 mutations impairing neurotrophin-4 signaling in patients with primary open-angle glaucoma. 15 Sep 2009
• Netrin participates in the development of retinotectal synaptic connectivity by modulating axon arborization and synapse formation in the developing brain. 7 Sep 2009
• Serum concentrations of s100b and NSE in migraine. 7 Sep 2009
• BDNF and NT-3 increase excitatory input connectivity in rat hippocampal cultures. 30 Aug 2009
• Can admission S-100beta predict the extent of brain damage in head trauma patients? 30 Aug 2009
• Possible neuroprotective effect of brimonidine in a mouse model of ischaemic optic neuropathy. 30 Aug 2009
• Elevated serum S100B protein and neuron-specific enolase levels in carbon monoxide poisoning. 30 Aug 2009
• Fates of neurotrophins after retrograde axonal transport: phosphorylation of p75NTR is a sorting signal for delayed degradation. 24 Aug 2009
• Knockout of the norepinephrine transporter and pharmacologically diverse antidepressants prevent behavioral and brain neurotrophin alterations in two chronic stress models of depression. 16 Aug 2009
• Gap junction inhibitors modulate S100B secretion in astrocyte cultures and acute hippocampal slices. 13 Aug 2009
• Changes in aqueous vascular endothelial growth factor and pigment epithelium-derived factor after ranibizumab alone or combined with verteporfin for exudative age-related macular degeneration. 9 Aug 2009
• The stochastic search dynamics of interneuron migration. 3 Aug 2009
• Homer regulates calcium signalling in growth cone turning. Aug 2009
• [Molecular-targeted therapy for motor neuron disease] 30 Jul 2009
• Prognostic significance of neuron-associated protein expression in non-muscle-invasive urothelial bladder cancer. 30 Jul 2009

See a longer list of these articles.

Technical information about 'Nerve Growth Factors'

Definition: Factors which enhance the growth potentialities of sensory and sympathetic nerve cells.

Registry Number: 0

Descriptor UI: D009414

Alternative terms: Nerve Growth Factors; Factors, Nerve Growth; Neurotrophic Factors; Factors, Neurotrophic; Neurotrophic Proteins; Neurotrophins; Neuronotrophic Factors; Factors, Neuronotrophic; Neurotrophic Protein; Growth-Associated Proteins, Neuronal; Growth Associated Proteins, Neuronal; Proteins, Neuronal Growth-Associated; Neuronal Growth-Associated Proteins; Neuronal Growth Associated Proteins; Neurite Outgrowth Factors; Factors, Neurite Outgrowth; Outgrowth Factors, Neurite;

Related Mesh Headings: Receptors, Nerve Growth Factor;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; agonists;

Tree Number: D12.644.276.860; D12.776.467.860; D12.776.641.600; D23.529.850;

History Note: 1980; use NERVE GROWTH FACTOR 1966-1979; for NEUROTROPHIC PROTEIN use NERVE GROWTH FACTORS (NM) 1978-1999

Technical Notes: NERVE GROWTH FACTOR is also available