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Nerve Tissue Proteins - Genetics
Research News and Information

Tuesday, November 24, 2009

Neuroligin-2 deletion selectively decreases inhibitory synaptic transmission originating from fast-spiking but not from somatostatin-positive interneurons.

2 Nov 2009 Neuroligins are cell adhesion molecules involved in synapse formation and/or function. Neurons express four neuroligins (NL1-NL4), of which NL1 is specific to excitatory and NL2 to inhibitory synapses. Excitatory and inhibitory synapses include ... Read more...


The heritability and genetics of frontotemporal lobar degeneration.

Nov 2009 BACKGROUND: Frontotemporal lobar degeneration (FTLD) is a genetically and pathologically heterogeneous neurodegenerative disorder. METHODS: We collected blood samples from a cohort of 225 patients with a diagnosis within the FTLD spectrum and ... Read more...


C-terminal region-dependent change of antibody-binding to the Eighth Reelin repeat reflects the signaling activity of Reelin.

30 Oct 2009 Reelin is a secreted glycoprotein that plays pivotal roles in the development and function of the brain, but how it activates downstream intracellular signaling is not fully understood. We have recently reported that the highly conserved C-terminal ... Read more...

 

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Technical information about 'Nerve Tissue Proteins'

Registry Number: 0

Descriptor UI: D009419

Alternative terms: Nerve Tissue Proteins; Proteins, Nerve Tissue; Tissue Proteins, Nerve;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; agonists;

Tree Number: D12.776.641;

Technical Notes: IM & coord with specific protein (IM) + specific nerve or nerve tissue (IM); /biosyn /drug eff /physiol /ultrastruct permitted

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