Neural Cell Adhesion Molecules
Research News and Information

Sunday, November 22, 2009

Aberrant expression of class III beta-tubulin in basal cell carcinoma of the skin.

29 Sep 2009 Tubulin is a major component of microtubules. Class III beta-tubulin (beta III) is a neuron-associated beta-tubulin isotype and expressed in the normal central and peripheral nervous systems. According to a previous study, beta III is not expressed ... Read more...

Role of glial cell line-derived neurotrophic factor (GDNF)-neural cell adhesion molecule (NCAM) interactions in induction of neurite outgrowth and identification of a binding site for NCAM in the heel region of GDNF.

7 Sep 2009 The formation of appropriate neuronal circuits is an essential part of nervous system development and relies heavily on the outgrowth of axons and dendrites and their guidance to their respective targets. This process is governed by a large array of ... Read more...

Culture system for rodent and human oligodendrocyte specification, lineage progression, and maturation.

30 Aug 2009 Here we document protocols for the production, isolation, and maintenance of the oligodendrocyte phenotype from rodent and human neural stem cells. Our unique method relies on a series of chemically defined media, specifically designed and carefully ... Read more...

Latest indexed articles for 'Neural Cell Adhesion Molecules'

These are the very latest articles for this heading:

• Aberrant expression of class III beta-tubulin in basal cell carcinoma of the skin. 29 Sep 2009
• Role of glial cell line-derived neurotrophic factor (GDNF)-neural cell adhesion molecule (NCAM) interactions in induction of neurite outgrowth and identification of a binding site for NCAM in the heel region of GDNF. 7 Sep 2009
• Culture system for rodent and human oligodendrocyte specification, lineage progression, and maturation. 30 Aug 2009
• Assessment of satellite cell number and activity status in human skeletal muscle biopsies. 30 Aug 2009
• Assay of diffusion of different botulinum neurotoxin type a formulations injected in the mouse leg. 30 Aug 2009
• Synaptic plasticity-associated proteases and protease inhibitors in the brain linked to the processing of extracellular matrix and cell adhesion molecules. 11 Aug 2009
• Modulation of synaptic transmission and plasticity by cell adhesion and repulsion molecules. 11 Aug 2009
• Clinical relevance of neuroendocrine differentiation in non-small cell lung cancer assessed by immunohistochemistry: a retrospective study on 405 surgically resected cases. 2 Aug 2009
• Follow-up association study of novel neuroticism gene MAMDC1. 30 Jul 2009
• Differential gene expression in the perichondrium and cartilage of the neonatal mouse temporomandibular joint. 30 Jul 2009
• Comprehensive profiling of the cell surface proteome of Sy5Y neuroblastoma cells yields a subset of proteins associated with tumor differentiation. 30 Jul 2009
• Postsynaptic Neuroligin1 regulates presynaptic maturation. 21 Jul 2009
• NCAM and polysialyltransferase profiles match dopaminergic marker gene expression but polysialic acid is dispensable for development of the midbrain dopamine system. 6 Jul 2009
• Brain development needs sugar: the role of polysialic acid in controlling NCAM functions. 29 Jun 2009
• Acute neuroinflammation in Lewis rats - a model for acute multiple sclerosis relapses. 24 Jun 2009
• Cell-cell adhesion in the prelaminar region of the optic nerve head: a possible target for ionic stress. 21 Jun 2009
• Expression of semaphorin 5A and its receptor plexin B3 contributes to invasion and metastasis of gastric carcinoma. 12 Jun 2009
• RBP-J promotes neuronal differentiation and inhibits oligodendroglial development in adult neurogenesis. 4 Jun 2009
• Role of non-HLA genetic variants in end-stage renal disease. 31 May 2009
• The novel chimeric anti-NCAM (neural cell adhesion molecule) antibody ch.MK1 displays antitumor activity in SCID mice but does not activate complement-dependent cytolysis (CDC). 30 May 2009

See a longer list of these articles.

Technical information about 'Neural Cell Adhesion Molecules'

Definition: Cell adhesion molecule involved in a diverse range of contact-mediated interactions among neurons, astrocytes, oligodendrocytes, and myotubes. It is widely but transiently expressed in many tissues early in embryogenesis. Four main isoforms exist, including CD56; (ANTIGENS, CD56); but there are many other variants resulting from alternative splicing and post-translational modifications. (From Pigott & Power, The Adhesion Molecule FactsBook, 1993, pp115-119)

Registry Number: 0

Descriptor UI: D019006

Alternative terms: Neural Cell Adhesion Molecules; NCAM; Neural Cell Adhesion Molecule; Cell Adhesion Molecules, Neural; Cell Adhesion Molecule, Neural;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; agonists;

Tree Number: D12.776.395.550.200.250.520; D12.776.543.550.200.250.520; D23.050.301.350.250.520;

History Note: 96

Technical Notes: NCAM: note X ref NEURAL CELL ADHESION MOLECULE but do not confuse this X ref with NEURONAL CELL ADHESION MOLECULES see CELL ADHESION MOLECULES, NEURONAL