Neural Inhibition - Genetics
Research News and Information

Sunday, November 22, 2009

Enhanced Stat3 activation in POMC neurons provokes negative feedback inhibition of leptin and insulin signaling in obesity.

14 Sep 2009 Leptin-stimulated Stat3 activation in proopiomelanocortin (POMC)-expressing neurons of the hypothalamus plays an important role in maintenance of energy homeostasis. While Stat3 activation in POMC neurons is required for POMC expression, the role of ... Read more...

Intact long-term potentiation but reduced connectivity between neocortical layer 5 pyramidal neurons in a mouse model of Rett syndrome.

7 Sep 2009 Mutations in MECP2 cause Rett syndrome and some related forms of mental retardation and autism. Mecp2-null mice exhibit symptoms reminiscent of Rett syndrome including deficits in learning. Previous reports demonstrated impaired long-term ... Read more...

Asynchronous transmitter release from cholecystokinin-containing inhibitory interneurons is widespread and target-cell independent.

7 Sep 2009 Neurotransmitter release at most central synapses is synchronized to the timing of presynaptic action potentials. Here, we show that three classes of depolarization-induced suppression of inhibition-expressing, cholecystokinin (CCK)-containing, ... Read more...

Latest indexed articles for 'Neural Inhibition - Genetics'

These are the very latest articles for this heading:

• Enhanced Stat3 activation in POMC neurons provokes negative feedback inhibition of leptin and insulin signaling in obesity. 14 Sep 2009
• Intact long-term potentiation but reduced connectivity between neocortical layer 5 pyramidal neurons in a mouse model of Rett syndrome. 7 Sep 2009
• Asynchronous transmitter release from cholecystokinin-containing inhibitory interneurons is widespread and target-cell independent. 7 Sep 2009
• Approach sensitivity in the retina processed by a multifunctional neural circuit. 4 Sep 2009
• Regionalized loss of parvalbumin interneurons in the cerebral cortex of mice with deficits in GFRalpha1 signaling. 24 Aug 2009
• Behavioral abnormalities in synapsin II knockout mice implicate a causal factor in schizophrenia. 30 Jul 2009
• Heritability of intracortical inhibition and facilitation. 13 Jul 2009
• Serotonergic hyperinnervation and effective serotonin blockade in an FGF receptor developmental model of psychosis. 29 Jun 2009
• Sensorimotor gating depends on polymorphisms of the serotonin-2A receptor and catechol-O-methyltransferase, but not on neuregulin-1 Arg38Gln genotype: a replication study. 26 Jun 2009
• A synaptic trek to autism. 19 Jun 2009
• Interaction between the effects of corticotropin-releasing factor and prepulse parameters on prepulse inhibition in two inbred rat strains and the F1 generation of a cross between them. 6 Jun 2009
• Buprenorphine is a weak partial agonist that inhibits opioid receptor desensitization. Jun 2009
• DRD3 Ser9Gly polymorphism is related to thermal pain perception and modulation in chronic widespread pain patients and healthy controls. 21 May 2009
• Expression patterns of 5-HT receptor subtypes 1A and 2A on GABAergic neurons within the spinal dorsal horn of GAD67-GFP knock-in mice. May 2009
• In silico whole genome association scan for murine prepulse inhibition. 14 Apr 2009
• Facilitatory actions of serotonin type 3 receptors on GABAergic inhibitory synaptic transmission in the spinal superficial dorsal horn. 13 Apr 2009
• Synaptic activity-mediated suppression of p53 and induction of nuclear calcium-regulated neuroprotective genes promote survival through inhibition of mitochondrial permeability transition. 6 Apr 2009
• Influence of SLC6A3 and COMT variation on neural activation during response inhibition. 26 Mar 2009
• GABAC receptor-mediated inhibition is altered but not eliminated in the superior colliculus of GABAC rho1 knockout mice. 23 Mar 2009
• Strain-dependent hippocampal protein levels of GABA(B)-receptor subunit 2 and NMDA-receptor subunit 1. 16 Mar 2009

See a longer list of these articles.

Technical information about 'Neural Inhibition'

Definition: The function of opposing or restraining the excitation of neurons or their target excitable cells.

Descriptor UI: D009433

Alternative terms: Neural Inhibition; Inhibition, Neural;

Related Mesh Headings: Refractory Period, Electrophysiological;

Allowable Qualifiers: drug effects; genetics; immunology; physiology; radiation effects; ethics;

Tree Number: G07.265.337.615; G07.700.240.615; G11.561.600.625;

Online Note: use NEURAL INHIBITION to search INHIBITION, NEURAL 1972-73 (as Prov)

History Note: 74; was INHIBITION, NEURAL 1972-73 (Prov)