Neurodegenerative Diseases
Research News and Information

Saturday, November 21, 2009

Postoperative nonconvulsive encephalopathic status: identification of a syndrome responsible for delayed progressive deterioration of neurological status after skull base surgery. Clinical article.

30 Oct 2009 OBJECT: Over a 10-year period, the authors have observed a rare but recurring syndrome manifested by a delayed, postoperative, progressive decline in the level of consciousness to deep coma that is time-limited to several days with abrupt awakening. ... Read more...

Epigenetic mechanisms in neurological diseases: genes, syndromes, and therapies.

30 Oct 2009 Epigenetic mechanisms such as DNA methylation and modifications to histone proteins regulate high-order DNA structure and gene expression. Aberrant epigenetic mechanisms are involved in the development of many diseases, including cancer. The ... Read more...

The APCs of neuroprotection.

17 Oct 2009 Mutations in the enzyme superoxide dismutase 1 (SOD1) have been linked to the neurodegenerative disease amyotrophic lateral sclerosis (ALS). In this issue of the JCI, Zhong et al. report that the endogenous anticoagulant activated protein C (APC) is ... Read more...

Latest indexed articles for 'Neurodegenerative Diseases'

These are the very latest articles for this heading:

• Postoperative nonconvulsive encephalopathic status: identification of a syndrome responsible for delayed progressive deterioration of neurological status after skull base surgery. Clinical article. 30 Oct 2009
• Epigenetic mechanisms in neurological diseases: genes, syndromes, and therapies. 30 Oct 2009
• The APCs of neuroprotection. 17 Oct 2009
• Immune activation in brain aging and neurodegeneration: too much or too little? 13 Oct 2009
• Harnessing immune alterations in neurodegenerative diseases. 13 Oct 2009
• Toxicants and neurodegenerative diseases special issue. 13 Oct 2009
• Nutrition, brain aging, and neurodegeneration. 12 Oct 2009
• Axonal transport defects in neurodegenerative diseases. 12 Oct 2009
• Four decades of neurodegenerative disease research: how far we have come! 12 Oct 2009
• The crystal structure of caspase-6, a selective effector of axonal degeneration. 10 Oct 2009
• Essential tremors: a family of neurodegenerative disorders? 29 Sep 2009
• A variable neurodegenerative phenotype with polymerase gamma mutation. 29 Sep 2009
• Glutamate agonist causes irreversible degeneration of inner hair cells. 21 Sep 2009
• A repertoire of rhythmic bursting produced by hypoglossal motoneurons in physiological and pathological conditions. 10 Sep 2009
• Neural damage associated with atopic diathesis: a nationwide survey in Japan. 6 Sep 2009
• On the mechanism of nonspecific inhibitors of protein aggregation: dissecting the interactions of alpha-synuclein with Congo red and Lacmoid. 6 Sep 2009
• Autopsy investigation of neurodegenerative disease transplant patients: hindsight is 20/20. 31 Aug 2009
• [Posterior cortical atrophy] 30 Aug 2009
• Novel therapeutics based on tau/microtubule dynamics: WO2008084483. 30 Aug 2009
• Magnesium in acute and chronic brain injury: an update. 30 Aug 2009

See a longer list of these articles.

Technical information about 'Neurodegenerative Diseases'

Definition: Hereditary and sporadic conditions which are characterized by progressive nervous system dysfunction. These disorders are often associated with atrophy of the affected central or peripheral nervous system structures.

Descriptor UI: D019636

Alternative terms: Neurodegenerative Diseases; Neurodegenerative Disease; Degenerative Diseases, Neurologic; Neurologic Degenerative Disease; Degenerative Neurologic Diseases; Degenerative Neurologic Disease; Neurologic Disease, Degenerative; Neurologic Diseases, Degenerative; Nervous System Degenerative Diseases; Neurodegenerative Disorders; Neurodegenerative Disorder; Neurologic Degenerative Conditions; Degenerative Condition, Neurologic; Degenerative Conditions, Neurologic; Neurologic Degenerative Condition; Neurologic Degenerative Diseases; Degenerative Diseases, Nervous System; Degenerative Neurologic Disorders; Degenerative Neurologic Disorder; Neurologic Disorder, Degenerative; Neurologic Disorders, Degenerative; Degenerative Diseases, Spinal Cord; Degenerative Diseases, Central Nervous System;

Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; congenital; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; urine; veterinary; ultrasonography; virology;

Tree Number: C10.574;

History Note: 98

Technical Notes: GEN or unspecified; prefer specifics; /genet: consider also HEREDODEGENERATIVE DISORDERS, NERVOUS SYSTEM