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Neurogenesis - Physiology
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Definition of 'Neurogenesis'

Formation of NEURONS which involves the differentiation and division of STEM CELLS in which one or both of the daughter cells become neurons.

Common names: Neurogenesis; Neurogeneses

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Sunday, November 22, 2009

Phosphorylation of ezrin/radixin/moesin proteins by LRRK2 promotes the rearrangement of actin cytoskeleton in neuronal morphogenesis.

2 Nov 2009 Leucine-rich repeat kinase 2 (LRRK2) functions as a putative protein kinase of ezrin, radixin, and moesin (ERM) family proteins. A Parkinson's disease-related G2019S substitution in the kinase domain of LRRK2 further enhances the phosphorylation of ... Read more...


Adult cerebrospinal fluid inhibits neurogenesis but facilitates gliogenesis from fetal rat neural stem cells.

30 Oct 2009 Neural stem cells (NSCs) are a promising source for cell replacement therapies for neurological diseases. Administration of NSCs into the cerebrospinal fluid (CSF) offers a nontraumatic transplantation method into the brain. However, cell survival ... Read more...


SUN1/2 and Syne/Nesprin-1/2 complexes connect centrosome to the nucleus during neurogenesis and neuronal migration in mice.

27 Oct 2009 Nuclear movement is critical during neurogenesis and neuronal migration, which are fundamental for mammalian brain development. Although dynein, Lis1, and other cytoplasmic proteins are known for their roles in connecting microtubules to the nucleus ... Read more...

 

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Technical information about 'Neurogenesis'

Definition: Formation of NEURONS which involves the differentiation and division of STEM CELLS in which one or both of the daughter cells become neurons.

Descriptor UI: D055495

Alternative terms: Neurogenesis; Neurogeneses;

Allowable Qualifiers: drug effects; genetics; immunology; physiology; radiation effects;

Tree Number: G04.299.151.912; G07.700.320.500.325.377.687; G08.686.785.760.170.450.500;

History Note: 2009

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