Neurogenesis - Radiation effects
Research News and Information

Sunday, November 22, 2009

The PPARalpha agonist fenofibrate preserves hippocampal neurogenesis and inhibits microglial activation after whole-brain irradiation.

30 Oct 2009 PURPOSE: Whole-brain irradiation (WBI) leads to cognitive impairment months to years after radiation. Numerous studies suggest that decreased hippocampal neurogenesis and microglial activation are involved in the pathogenesis of WBI-induced brain ... Read more...

Ionizing radiation impairs the formation of trace fear memories and reduces hippocampal neurogenesis.

29 Sep 2009 Long-term cognitive impairments are a feared consequence of therapeutic cranial irradiation in children as well as adults. Studies in animal models suggest that these deficits may be associated with a decrease in hippocampal granule cell ... Read more...

Neurogenesis-dependent and -independent effects of fluoxetine in an animal model of anxiety/depression.

26 May 2009 Understanding the physiopathology of affective disorders and their treatment relies on the availability of experimental models that accurately mimic aspects of the disease. Here we describe a mouse model of an anxiety/depressive-like state induced ... Read more...

Latest indexed articles for 'Neurogenesis - Radiation effects'

These are the very latest articles for this heading:

• The PPARalpha agonist fenofibrate preserves hippocampal neurogenesis and inhibits microglial activation after whole-brain irradiation. 30 Oct 2009
• Ionizing radiation impairs the formation of trace fear memories and reduces hippocampal neurogenesis. 29 Sep 2009
• Neurogenesis-dependent and -independent effects of fluoxetine in an animal model of anxiety/depression. 26 May 2009
• Continuous exposure to 900MHz GSM-modulated EMF alters morphological maturation of neural cells. 22 Mar 2009
• Immunohistochemical study of postnatal neurogenesis after whole-body exposure to electromagnetic fields: evaluation of age- and dose-related changes in rats. 19 Mar 2009
• Optical neuronal guidance in three-dimensional matrices. 19 Feb 2009
• Prenatal exposures to LTP-patterned magnetic fields: quantitative effects on specific limbic structures and acquisition of contextually conditioned fear. 30 Dec 2008
• Inhibition of adult hippocampal neurogenesis disrupts contextual learning but spares spatial working memory, long-term conditional rule retention and spatial reversal. 14 Dec 2008
• Space radiation-induced inhibition of neurogenesis in the hippocampal dentate gyrus and memory impairment in mice: ameliorative potential of the melatonin metabolite, AFMK. 30 Jun 2008
• Cranial radiation therapy and damage to hippocampal neurogenesis. 30 Dec 2007
• Radiation effects on neural precursor cells in the dentate gyrus. 3 Sep 2007
• Light deprivation delays morphological differentiation of bipolar cells in the rabbit retina. 25 Jul 2007

See a longer list of these articles.

Technical information about 'Neurogenesis'

Definition: Formation of NEURONS which involves the differentiation and division of STEM CELLS in which one or both of the daughter cells become neurons.

Descriptor UI: D055495

Alternative terms: Neurogenesis; Neurogeneses;

Allowable Qualifiers: drug effects; genetics; immunology; physiology; radiation effects;

Tree Number: G04.299.151.912; G07.700.320.500.325.377.687; G08.686.785.760.170.450.500;

History Note: 2009