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Neurogranin - Chemistry
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Definition of 'Neurogranin'

A BRAIN-specific substrate for PROTEIN KINASE C that binds CALMODULIN and is involved in regulation of CALCIUM SIGNALING.

Common names: Neurogranin; RC3 Protein (Neurogranin); P17 Protein Kinase C Substrate

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Monday, November 23, 2009

Conservation and expression of IQ-domain-containing calpacitin gene products (neuromodulin/GAP-43, neurogranin/RC3) in the adult and developing oscine song control system.

30 Jan 2009 Songbirds are appreciated for the insights they provide into regulated neural plasticity. Here, we describe the comparative analysis and brain expression of two gene sequences encoding probable regulators of synaptic plasticity in songbirds: ... Read more...


Enzymatic characteristics of a Ser/Thr protein kinase, SpkA, from Myxococcus xanthus.

30 Dec 2008 Two Ser/Thr protein kinases, SpkA and SpkB, selected from Myxococcus xanthus based on amino acid sequence similarities with the catalytic subunits of cAMP-dependent protein kinases (PKA) were synthesized using a cell-free protein synthesis system. ... Read more...


IQ-motif proteins influence intracellular free Ca2+ in hippocampal neurons through their interactions with calmodulin.

22 Oct 2007 Calmodulin (CaM) is most recognized for its role in activating Ca(2+)-CaM-dependent enzymes following increased intracellular Ca(2+). However, CaM's high intracellular concentration indicates CaM has the potential to play a significant role as a ... Read more...

 

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Technical information about 'Neurogranin'

Definition: A BRAIN-specific substrate for PROTEIN KINASE C that binds CALMODULIN and is involved in regulation of CALCIUM SIGNALING.

Registry Number: 132654-77-4

Descriptor UI: D051579

Alternative terms: Neurogranin; RC3 Protein (Neurogranin); P17 Protein Kinase C Substrate;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; agonists;

Tree Number: D12.776.157.142.500; D12.776.641.640;

History Note: 2006(1991)

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