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Neuromuscular Blocking Agents - Adverse effects
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Definition of 'Neuromuscular Blocking Agents'

Drugs that interrupt transmission of nerve impulses at the skeletal neuromuscular junction. They can be of two types, competitive, stabilizing blockers (NEUROMUSCULAR NONDEPOLARIZING AGENTS) or noncompetitive, depolarizing agents (NEUROMUSCULAR DEPOLARIZING AGENTS). Both prevent acetylcholine from triggering the muscle contraction and they are used as anesthesia adjuvants, as relaxants during electroshock, in convulsive states, etc.

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Monday, November 23, 2009

Perioperative anaphylaxis.

30 Jul 2009 The incidence of immune-mediated anaphylaxis during anesthesia ranges from 1 in 10,000 to 1 in 20,000. Neuromuscular blocking agents represent the most frequently involved substances, followed by latex and antibiotics, but every drug or substance ... Read more...


The pholcodine story.

30 Jul 2009 Anaphylactic reactions to neuromuscular blocking agents during general anesthesia constitute a major cause of concern and a great source of debate among anesthesiologists. The authors' recent investigations, taking the striking differences of ... Read more...


[Muscle relaxants in the ICU]

11 May 2009 Neuromuscular blockade in ICU patients has become less popular, in particular since non-invasive methods of artificial respiration have been introduced. Succinylcholine has numerous side effects. Due to its short onset, Rocuronium may be an ... Read more...

 

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Technical information about 'Neuromuscular Blocking Agents'

Definition: Drugs that interrupt transmission of nerve impulses at the skeletal neuromuscular junction. They can be of two types, competitive, stabilizing blockers (NEUROMUSCULAR NONDEPOLARIZING AGENTS) or noncompetitive, depolarizing agents (NEUROMUSCULAR DEPOLARIZING AGENTS). Both prevent acetylcholine from triggering the muscle contraction and they are used as anesthesia adjuvants, as relaxants during electroshock, in convulsive states, etc.

Registry Number: 0

Descriptor UI: D009466

Alternative terms: Neuromuscular Blocking Agents; Agents, Neuromuscular Blocking; Blocking Agents, Neuromuscular; Neuromuscular Blockers; Blockers, Neuromuscular;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D27.505.696.663.700.710;

Online Note: search CURARE-LIKE AGENTS & NEUROMUSCULAR DEPOLARIZING AGENTS 1970-74

History Note: 75; was see under CURARE-LIKE AGENTS & NEUROMUSCULAR DEPOLARIZING AGENTS 1970-74

Technical Notes: GEN or unspecified; prefer specifics; consider also NEUROMUSCULAR JUNCTION /drug eff

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