Neuromuscular Blocking Agents
Research News and Information

Sunday, November 22, 2009

Neuromuscular block differentially affects immobility and cortical activation at near-minimum alveolar concentration anesthesia.

29 Sep 2009 BACKGROUND: Anesthesia-induced immobility and cortical suppression are governed by anatomically separate, but interacting, areas of the central nervous system. Consequently, larger volatile anesthetic concentrations are required to suppress cortical ... Read more...

Clinical predictors of duration of action of cisatracurium and rocuronium administered long-term.

30 Aug 2009 BACKGROUND: The duration of action of neuromuscular blocking drugs (NBDs) varies between individuals and even within individuals in different settings. OBJECTIVES: To define predictors of variance in duration of action of rocuronium and ... Read more...

Perioperative anaphylaxis.

30 Jul 2009 The incidence of immune-mediated anaphylaxis during anesthesia ranges from 1 in 10,000 to 1 in 20,000. Neuromuscular blocking agents represent the most frequently involved substances, followed by latex and antibiotics, but every drug or substance ... Read more...

Latest indexed articles for 'Neuromuscular Blocking Agents'

These are the very latest articles for this heading:

• Anaphylaxis and anesthesia: controversies and new insights. 30 Oct 2009
• Neuromuscular block differentially affects immobility and cortical activation at near-minimum alveolar concentration anesthesia. 29 Sep 2009
• Clinical predictors of duration of action of cisatracurium and rocuronium administered long-term. 30 Aug 2009
• Anaesthesia for a patient with Isaac's syndrome and myasthenia gravis. 30 Aug 2009
• Perioperative anaphylaxis. 30 Jul 2009
• The pholcodine story. 30 Jul 2009
• Sedation and analgesia in the pediatric intensive care unit following laryngotracheal reconstruction. 29 Jun 2009
• Advances in anesthesia, preoperative and pain management. Introduction. 29 Jun 2009
• Current concepts in neuromuscular transmission. 29 Jun 2009
• Tracheal intubation without neuromuscular blocking drugs. 30 May 2009
• Reversal of neuromuscular block. 22 May 2009
• Avoidance of neuromuscular blocking agents may increase the risk of difficult tracheal intubation: a cohort study of 103,812 consecutive adult patients recorded in the Danish Anaesthesia Database. 18 May 2009
• Neuromuscular activity of BaTX, a presynaptic basic PLA2 isolated from Bothrops alternatus snake venom. 18 May 2009
• [Sugammadex--a new era in the antagonsim of muscle relaxants] 11 May 2009
• [Muscle relaxants in the ICU] 11 May 2009
• Emergency airway management in critically injured patients: a survey of U.S. aero-medical transport programs. 15 Apr 2009
• Is the decreasing availability of vecuronium and pancuronium putting patients at risk? 30 Mar 2009
• Neuromuscular blockade, reversal agent use, and operating room time: retrospective analysis of US inpatient surgeries. 30 Mar 2009
• Acceleromyography and mechanomyography for establishing potency of neuromuscular blocking agents: a randomized-controlled trial. 30 Mar 2009
• Improving the prediction of a neuromuscular block. 30 Mar 2009

See a longer list of these articles.

Technical information about 'Neuromuscular Blocking Agents'

Definition: Drugs that interrupt transmission of nerve impulses at the skeletal neuromuscular junction. They can be of two types, competitive, stabilizing blockers (NEUROMUSCULAR NONDEPOLARIZING AGENTS) or noncompetitive, depolarizing agents (NEUROMUSCULAR DEPOLARIZING AGENTS). Both prevent acetylcholine from triggering the muscle contraction and they are used as anesthesia adjuvants, as relaxants during electroshock, in convulsive states, etc.

Registry Number: 0

Descriptor UI: D009466

Alternative terms: Neuromuscular Blocking Agents; Agents, Neuromuscular Blocking; Blocking Agents, Neuromuscular; Neuromuscular Blockers; Blockers, Neuromuscular;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D27.505.696.663.700.710;

Online Note: search CURARE-LIKE AGENTS & NEUROMUSCULAR DEPOLARIZING AGENTS 1970-74

History Note: 75; was see under CURARE-LIKE AGENTS & NEUROMUSCULAR DEPOLARIZING AGENTS 1970-74

Technical Notes: GEN or unspecified; prefer specifics; consider also NEUROMUSCULAR JUNCTION /drug eff