Neuromuscular Junction - Embryology
Research News and Information

Monday, November 23, 2009

The vesicular acetylcholine transporter is required for neuromuscular development and function.

25 Jul 2009 The vesicular acetylcholine (ACh) transporter (VAChT) mediates ACh storage by synaptic vesicles. However, the VAChT-independent release of ACh is believed to be important during development. Here we generated VAChT knockout mice and tested the ... Read more...

Abnormal development of the neuromuscular junction in Nedd4-deficient mice.

30 Mar 2009 Nedd4 (neural precursor cell expressed developmentally down-regulated gene 4) is an E3 ubiquitin ligase highly conserved from yeast to humans. The expression of Nedd4 is developmentally down-regulated in the mammalian nervous system, but the role of ... Read more...

Embryonic overexpression of Galgt2 inhibits skeletal muscle growth via activation of myostatin signaling.

30 Dec 2008 Many proteins that affect skeletal muscle growth are secreted glycoproteins, yet the nature of how glycosylation regulates the expression and growth-promoting properties of such factors is not well understood. One type of glycosylation that affects ... Read more...

Latest indexed articles for 'Neuromuscular Junction - Embryology'

These are the very latest articles for this heading:

• The vesicular acetylcholine transporter is required for neuromuscular development and function. 25 Jul 2009
• Abnormal development of the neuromuscular junction in Nedd4-deficient mice. 30 Mar 2009
• Embryonic overexpression of Galgt2 inhibits skeletal muscle growth via activation of myostatin signaling. 30 Dec 2008
• A mammalian homolog of Drosophila tumorous imaginal discs, Tid1, mediates agrin signaling at the neuromuscular junction. 24 Nov 2008
• New dogs in the dogma: Lrp4 and Tid1 in neuromuscular synapse formation. 24 Nov 2008
• The mammalian myotome: a muscle with no innervation. 30 Oct 2008
• LRP4 serves as a coreceptor of agrin. 21 Oct 2008
• Characterization of ionotropic glutamate receptors in insect neuro-muscular junction. 29 Jul 2008
• Embryonic motor axon development in the severe SMA mouse. Jul 2008
• Age-related changes in the neuromuscular development of the internal anal sphincter. 30 May 2008
• The rescue of developing avian motoneurons from programmed cell death by a selective inhibitor of the fetal muscle-specific nicotinic acetylcholine receptor. 30 May 2008
• Essential roles of the acetylcholine receptor gamma-subunit in neuromuscular synaptic patterning. 21 Apr 2008
• Key aspects of phrenic motoneuron and diaphragm muscle development during the perinatal period. 8 Apr 2008
• Beta-catenin in reverse action. 28 Feb 2008
• FM 1-43 labeling of synaptic vesicle pools at the Drosophila neuromuscular junction. 30 Dec 2007
• Selective targeting of different neural cell adhesion molecule isoforms during motoneuron myotube synapse formation in culture and the switch from an immature to mature form of synaptic vesicle cycling. 24 Dec 2007
• AChR channel conversion and AChR-adjusted neuronal survival during embryonic development. 13 Dec 2007
• Morphologic analysis of the neuromuscular development of the anorectal unit in fetal rats with retinoic acid induced myelomeningocele. 15 Nov 2007
• Dp71, utrophin and beta-dystroglycan expression and distribution in PC12/L6 cell cocultures. 27 Oct 2007
• Presynaptic establishment of the synaptic cleft extracellular matrix is required for post-synaptic differentiation. 25 Sep 2007

See a longer list of these articles.

Technical information about 'Neuromuscular Junction'

Definition: The synapse between a neuron and a muscle.

Descriptor UI: D009469

Alternative terms: Neuromuscular Junction; Junction, Neuromuscular; Junctions, Neuromuscular; Neuromuscular Junctions; Myoneural Junction; Junction, Myoneural; Junctions, Myoneural; Myoneural Junctions; Nerve-Muscle Preparation; Nerve Muscle Preparation; Nerve-Muscle Preparations; Preparation, Nerve-Muscle; Preparations, Nerve-Muscle;

Related Mesh Headings: Neuromuscular Blocking Agents; Neuromuscular Depolarizing Agents; Receptors, Cholinergic;

Allowable Qualifiers: abnormalities; anatomy & histology; blood supply; cytology; drug effects; embryology; enzymology; growth & development; immunology; injuries; metabolism; microbiology; parasitology; pathology; physiology; physiopathology; radiation effects; radiography; radionuclide imaging; secretion; surgery; ultrastructure; ultrasonography; chemistry; virology; genetics;

Tree Number: A08.800.550.550.550; A08.850.550.550; A11.284.149.165.420.780.550.550;

Online Note: use NEUROMUSCULAR JUNCTION to search MYONEURAL JUNCTION 1966-67

History Note: 68; was MYONEURAL JUNCTION 1963-67

Technical Notes: /drug eff: consider also NEUROMUSCULAR BLOCKING AGENTS or NEUROMUSCULAR DEPOLARIZING AGENTS; neuromusc transm = NEUROMUSCULAR JUNCTION /physiol + NEURAL TRANSMISSION; dis = NEUROMUSCULAR JUNCTION DISEASES