Neuromuscular Junction - Enzymology
Research News and Information

Sunday, November 22, 2009

UNC-108/RAB-2 and its effector RIC-19 are involved in dense core vesicle maturation in Caenorhabditis elegans.

19 Sep 2009 Small guanosine triphosphatases of the Rab family regulate intracellular vesicular trafficking. Rab2 is highly expressed in the nervous system, yet its function in neurons is unknown. In Caenorhabditis elegans, unc-108/rab-2 mutants have been ... Read more...

The proteasome-associated deubiquitinating enzyme Usp14 is essential for the maintenance of synaptic ubiquitin levels and the development of neuromuscular junctions.

31 Aug 2009 Dysfunction of the ubiquitin proteasome system (UPS) has been implicated in the pathogenesis of many neurological diseases, including Alzheimer's, spinocerebellar ataxia, and several motor neuron diseases. Recent research indicates that changes in ... Read more...

Acetylcholinesterase inhibitors in MG: to be or not to be?

30 May 2009 Myasthenia gravis (MG) is an autoimmune disorder usually caused by antibodies against either the acetylcholine receptor (AChR) or muscle-specific tyrosine kinase (MuSK) at the neuromuscular junction. Neuromuscular transmission failure results in ... Read more...

Latest indexed articles for 'Neuromuscular Junction - Enzymology'

These are the very latest articles for this heading:

• UNC-108/RAB-2 and its effector RIC-19 are involved in dense core vesicle maturation in Caenorhabditis elegans. 19 Sep 2009
• The proteasome-associated deubiquitinating enzyme Usp14 is essential for the maintenance of synaptic ubiquitin levels and the development of neuromuscular junctions. 31 Aug 2009
• Acetylcholinesterase inhibitors in MG: to be or not to be? 30 May 2009
• Cholinesterases and the basal lamina at vertebrate neuromuscular junctions. 3 May 2009
• [Energetic applications: Na+/K+-ATPase and neuromuscular transmission] 21 Feb 2009
• Function of neuromuscular synapses in the zebrafish choline-acetyltransferase mutant bajan. 4 Aug 2008
• Synaptogenetic mechanisms controlling postsynaptic differentiation of the neuromuscular junction are nerve-dependent in human and nerve-independent in mouse C2C12 muscle cultures. 25 May 2008
• Assembly and regulation of acetylcholinesterase at the vertebrate neuromuscular junction. 25 May 2008
• Acetylcholinesterase expression in muscle is specifically controlled by a promoter-selective enhancesome in the first intron. 3 Mar 2008
• Proteasome function is required to maintain muscle cellular architecture. 30 Oct 2007
• Calpain activation impairs neuromuscular transmission in a mouse model of the slow-channel myasthenic syndrome. 29 Sep 2007
• Activation of Matrix Metalloproteinase-3 is altered at the frog neuromuscular junction following changes in synaptic activity. 13 Sep 2007
• Rat alpha- and gamma-motoneuron soma size and succinate dehydrogenase activity are independent of neuromuscular activity level. 30 Jul 2007
• Acetylcholinesterase mobility and stability at the neuromuscular junction of living mice. 28 May 2007
• Synaptic components necessary for retrograde signaling triggered by calcium/calmodulin-dependent protein kinase II during synaptogenesis. 7 Feb 2007
• The ubiquitin-proteasome system postsynaptically regulates glutamatergic synaptic function. 6 Feb 2007
• Sir Bernard Katz: 26 March 1911 - 20 April 2003. 30 Dec 2006
• At the next stop sign turn right: the metalloprotease Tolloid-related 1 controls defasciculation of motor axons in Drosophila. 11 Sep 2006
• Outcome of acetylcholinesterase deficiency for neuromuscular functioning. 30 Jul 2006
• Rewiring enervated: thinking LARGEr than myodystrophy. 30 Jul 2006

See a longer list of these articles.

Technical information about 'Neuromuscular Junction'

Definition: The synapse between a neuron and a muscle.

Descriptor UI: D009469

Alternative terms: Neuromuscular Junction; Junction, Neuromuscular; Junctions, Neuromuscular; Neuromuscular Junctions; Myoneural Junction; Junction, Myoneural; Junctions, Myoneural; Myoneural Junctions; Nerve-Muscle Preparation; Nerve Muscle Preparation; Nerve-Muscle Preparations; Preparation, Nerve-Muscle; Preparations, Nerve-Muscle;

Related Mesh Headings: Neuromuscular Blocking Agents; Neuromuscular Depolarizing Agents; Receptors, Cholinergic;

Allowable Qualifiers: abnormalities; anatomy & histology; blood supply; cytology; drug effects; embryology; enzymology; growth & development; immunology; injuries; metabolism; microbiology; parasitology; pathology; physiology; physiopathology; radiation effects; radiography; radionuclide imaging; secretion; surgery; ultrastructure; ultrasonography; chemistry; virology; genetics;

Tree Number: A08.800.550.550.550; A08.850.550.550; A11.284.149.165.420.780.550.550;

Online Note: use NEUROMUSCULAR JUNCTION to search MYONEURAL JUNCTION 1966-67

History Note: 68; was MYONEURAL JUNCTION 1963-67

Technical Notes: /drug eff: consider also NEUROMUSCULAR BLOCKING AGENTS or NEUROMUSCULAR DEPOLARIZING AGENTS; neuromusc transm = NEUROMUSCULAR JUNCTION /physiol + NEURAL TRANSMISSION; dis = NEUROMUSCULAR JUNCTION DISEASES