Neuromuscular Junction - Metabolism
Research News and Information

Saturday, November 21, 2009

Postsynaptic regulation of synaptic plasticity by synaptotagmin 4 requires both C2 domains.

10 Oct 2009 Ca(2+) influx into synaptic compartments during activity is a key mediator of neuronal plasticity. Although the role of presynaptic Ca(2+) in triggering vesicle fusion though the Ca(2+) sensor synaptotagmin 1 (Syt 1) is established, molecular ... Read more...

Molecular mechanisms that enhance synapse stability despite persistent disruption of the spectrin/ankyrin/microtubule cytoskeleton.

3 Oct 2009 Loss of spectrin or ankyrin in the presynaptic motoneuron disrupts the synaptic microtubule cytoskeleton and leads to disassembly of the neuromuscular junction (NMJ). Here, we demonstrate that NMJ disassembly after loss of alpha-spectrin can be ... Read more...

Autophagy promotes synapse development in Drosophila.

26 Sep 2009 Autophagy, a lysosome-dependent degradation mechanism, mediates many biological processes, including cellular stress responses and neuroprotection. In this study, we demonstrate that autophagy positively regulates development of the Drosophila ... Read more...

Latest indexed articles for 'Neuromuscular Junction - Metabolism'

These are the very latest articles for this heading:

• Postsynaptic regulation of synaptic plasticity by synaptotagmin 4 requires both C2 domains. 10 Oct 2009
• Molecular mechanisms that enhance synapse stability despite persistent disruption of the spectrin/ankyrin/microtubule cytoskeleton. 3 Oct 2009
• Autophagy promotes synapse development in Drosophila. 26 Sep 2009
• The proteasome-associated deubiquitinating enzyme Usp14 is essential for the maintenance of synaptic ubiquitin levels and the development of neuromuscular junctions. 31 Aug 2009
• Obidoxime in acute organophosphate poisoning: 1 - clinical effectiveness. 30 Aug 2009
• Obidoxime in acute organophosphate poisoning: 2 - PK/PD relationships. 30 Aug 2009
• Glia and muscle sculpt neuromuscular arbors by engulfing destabilized synaptic boutons and shed presynaptic debris. 23 Aug 2009
• Selective remodeling: refining neural connectivity at the neuromuscular junction. 23 Aug 2009
• Structural and functional diversity of novel coronin 1C (CRN2) isoforms in muscle. Aug 2009
• A critical step for postsynaptic F-actin organization: regulation of Baz/Par-3 localization by aPKC and PTEN. 30 Jul 2009
• The vesicular acetylcholine transporter is required for neuromuscular development and function. 25 Jul 2009
• Identification of an agrin mutation that causes congenital myasthenia and affects synapse function. 21 Jul 2009
• The formation of acetylcholine receptor clusters visualized with quantum dots. 14 Jul 2009
• Maturation of active zone assembly by Drosophila Bruchpilot. 11 Jul 2009
• Zebrafish survival motor neuron mutants exhibit presynaptic neuromuscular junction defects. 8 Jul 2009
• Graded synaptic transmission at the Caenorhabditis elegans neuromuscular junction. 13 Jun 2009
• In vivo fluorescence imaging with high-resolution microlenses. 12 Jun 2009
• Myasthenia gravis associated with etanercept therapy. 30 May 2009
• Synapsin I accelerates the kinetics of neurotransmitter release in mouse motor terminals. 30 May 2009
• Regulation of acetylcholine receptor clustering by ADF/cofilin-directed vesicular trafficking. 29 May 2009

See a longer list of these articles.

Technical information about 'Neuromuscular Junction'

Definition: The synapse between a neuron and a muscle.

Descriptor UI: D009469

Alternative terms: Neuromuscular Junction; Junction, Neuromuscular; Junctions, Neuromuscular; Neuromuscular Junctions; Myoneural Junction; Junction, Myoneural; Junctions, Myoneural; Myoneural Junctions; Nerve-Muscle Preparation; Nerve Muscle Preparation; Nerve-Muscle Preparations; Preparation, Nerve-Muscle; Preparations, Nerve-Muscle;

Related Mesh Headings: Neuromuscular Blocking Agents; Neuromuscular Depolarizing Agents; Receptors, Cholinergic;

Allowable Qualifiers: abnormalities; anatomy & histology; blood supply; cytology; drug effects; embryology; enzymology; growth & development; immunology; injuries; metabolism; microbiology; parasitology; pathology; physiology; physiopathology; radiation effects; radiography; radionuclide imaging; secretion; surgery; ultrastructure; ultrasonography; chemistry; virology; genetics;

Tree Number: A08.800.550.550.550; A08.850.550.550; A11.284.149.165.420.780.550.550;

Online Note: use NEUROMUSCULAR JUNCTION to search MYONEURAL JUNCTION 1966-67

History Note: 68; was MYONEURAL JUNCTION 1963-67

Technical Notes: /drug eff: consider also NEUROMUSCULAR BLOCKING AGENTS or NEUROMUSCULAR DEPOLARIZING AGENTS; neuromusc transm = NEUROMUSCULAR JUNCTION /physiol + NEURAL TRANSMISSION; dis = NEUROMUSCULAR JUNCTION DISEASES