Neuromuscular Junction
Research News and Information

Saturday, November 21, 2009

Trans-synaptic transmission of vesicular Wnt signals through Evi/Wntless.

14 Oct 2009 Wnts play pivotal roles during development and in the mature nervous system. However, the mechanism by which Wnts traffic between cells has remained elusive. Here we demonstrate a mechanism of Wnt transmission through release of exosome-like ... Read more...

Postsynaptic regulation of synaptic plasticity by synaptotagmin 4 requires both C2 domains.

10 Oct 2009 Ca(2+) influx into synaptic compartments during activity is a key mediator of neuronal plasticity. Although the role of presynaptic Ca(2+) in triggering vesicle fusion though the Ca(2+) sensor synaptotagmin 1 (Syt 1) is established, molecular ... Read more...

Molecular mechanisms that enhance synapse stability despite persistent disruption of the spectrin/ankyrin/microtubule cytoskeleton.

3 Oct 2009 Loss of spectrin or ankyrin in the presynaptic motoneuron disrupts the synaptic microtubule cytoskeleton and leads to disassembly of the neuromuscular junction (NMJ). Here, we demonstrate that NMJ disassembly after loss of alpha-spectrin can be ... Read more...

Latest indexed articles for 'Neuromuscular Junction'

These are the very latest articles for this heading:

• Trans-synaptic transmission of vesicular Wnt signals through Evi/Wntless. 14 Oct 2009
• Postsynaptic regulation of synaptic plasticity by synaptotagmin 4 requires both C2 domains. 10 Oct 2009
• Molecular mechanisms that enhance synapse stability despite persistent disruption of the spectrin/ankyrin/microtubule cytoskeleton. 3 Oct 2009
• The effect of gender on compensatory neuromuscular response to upper airway obstruction in normal subjects under midazolam general anesthesia. 29 Sep 2009
• Autophagy promotes synapse development in Drosophila. 26 Sep 2009
• The primary locus of motor neuron death in an ALS-PDC mouse model. 21 Sep 2009
• Motoneuron transplantation rescues the phenotype of SMARD1 (spinal muscular atrophy with respiratory distress type 1). 21 Sep 2009
• UNC-108/RAB-2 and its effector RIC-19 are involved in dense core vesicle maturation in Caenorhabditis elegans. 19 Sep 2009
• PP2A and GSK-3beta act antagonistically to regulate active zone development. 14 Sep 2009
• A new ion channel blooms at the synapse. 8 Sep 2009
• The proteasome-associated deubiquitinating enzyme Usp14 is essential for the maintenance of synaptic ubiquitin levels and the development of neuromuscular junctions. 31 Aug 2009
• The biomechanics of cycling with a transtibial amputation: Recommendations for prosthetic design and direction for future research. 30 Aug 2009
• Isolation, complete amino acid sequence and characterization of a previously unreported post-synaptic neurotoxin - AlphaN3, from the venom of Bungarus candidus. 30 Aug 2009
• Obidoxime in acute organophosphate poisoning: 1 - clinical effectiveness. 30 Aug 2009
• Obidoxime in acute organophosphate poisoning: 2 - PK/PD relationships. 30 Aug 2009
• WNTs tune up the neuromuscular junction. 30 Aug 2009
• Suxamethonium stands the test of time: it is too early to say goodbye. 30 Aug 2009
• MSC p43 required for axonal development in motor neurons. 24 Aug 2009
• Glia and muscle sculpt neuromuscular arbors by engulfing destabilized synaptic boutons and shed presynaptic debris. 23 Aug 2009
• Selective remodeling: refining neural connectivity at the neuromuscular junction. 23 Aug 2009

See a longer list of these articles.

Technical information about 'Neuromuscular Junction'

Definition: The synapse between a neuron and a muscle.

Descriptor UI: D009469

Alternative terms: Neuromuscular Junction; Junction, Neuromuscular; Junctions, Neuromuscular; Neuromuscular Junctions; Myoneural Junction; Junction, Myoneural; Junctions, Myoneural; Myoneural Junctions; Nerve-Muscle Preparation; Nerve Muscle Preparation; Nerve-Muscle Preparations; Preparation, Nerve-Muscle; Preparations, Nerve-Muscle;

Related Mesh Headings: Neuromuscular Blocking Agents; Neuromuscular Depolarizing Agents; Receptors, Cholinergic;

Allowable Qualifiers: abnormalities; anatomy & histology; blood supply; cytology; drug effects; embryology; enzymology; growth & development; immunology; injuries; metabolism; microbiology; parasitology; pathology; physiology; physiopathology; radiation effects; radiography; radionuclide imaging; secretion; surgery; ultrastructure; ultrasonography; chemistry; virology; genetics;

Tree Number: A08.800.550.550.550; A08.850.550.550; A11.284.149.165.420.780.550.550;

Online Note: use NEUROMUSCULAR JUNCTION to search MYONEURAL JUNCTION 1966-67

History Note: 68; was MYONEURAL JUNCTION 1963-67

Technical Notes: /drug eff: consider also NEUROMUSCULAR BLOCKING AGENTS or NEUROMUSCULAR DEPOLARIZING AGENTS; neuromusc transm = NEUROMUSCULAR JUNCTION /physiol + NEURAL TRANSMISSION; dis = NEUROMUSCULAR JUNCTION DISEASES