Neurons - Drug effects
Research News and Information

Saturday, November 21, 2009

p38SJ, a novel DINGG protein protects neuronal cells from alcohol induced injury and death.

29 Nov 2009 Ethanol induces neuronal cell injury and death by dysregulating several signaling events that are controlled, in part, by activation of MAPK/ERK1/2 and/or inactivation of its corresponding phosphatase, PP1. Recently, we have purified a novel protein ... Read more...

Calcium/calmodulin-dependent protein kinase type IV is a target gene of the Wnt/beta-catenin signaling pathway.

29 Nov 2009 Calcium/calmodulin-dependent protein kinase IV (CaMKIV) plays a key role in the regulation of calcium-dependent gene expression. The expression of CaMKIV and the activation of CREB regulated genes are involved in memory and neuronal survival. We ... Read more...

Proteasome inhibition modulates kinase activation in neural cells: relevance to ubiquitination, ribosomes, and survival.

30 Oct 2009 In this study we examined whether established signal transduction cascades, p44/42 mitogen-activated protein kinase (ERK1/2) and Jun N-terminal kinases (JNK) pathways, are altered in N2a neural cells in response to proteasome inhibition. ... Read more...

Latest indexed articles for 'Neurons - Drug effects'

These are the very latest articles for this heading:

• p38SJ, a novel DINGG protein protects neuronal cells from alcohol induced injury and death. 29 Nov 2009
• Calcium/calmodulin-dependent protein kinase type IV is a target gene of the Wnt/beta-catenin signaling pathway. 29 Nov 2009
• Proteasome inhibition modulates kinase activation in neural cells: relevance to ubiquitination, ribosomes, and survival. 30 Oct 2009
• Rapid use-dependent down-regulation of gamma-aminobutyric acid type A receptors in rat mesencephalic trigeminal neurons. 30 Oct 2009
• Contribution of Kv channel subunits to glutamate-induced apoptosis in cultured rat hippocampal neurons. 30 Oct 2009
• Role of p75 neurotrophin receptor in isoflurane-mediated neuronal changes. 30 Oct 2009
• Metaplasticity governs natural experience-driven plasticity of nascent embryonic brain circuits. 27 Oct 2009
• Dual palmitoylation of NR2 subunits regulates NMDA receptor trafficking. 27 Oct 2009
• The time course of dopamine transmission in the ventral tegmental area. 19 Oct 2009
• Nitric oxide potentiation of locomotor activity in the spinal cord of the lamprey. 19 Oct 2009
• Prostaglandin E2-induced masculinization of brain and behavior requires protein kinase A, AMPA/kainate, and metabotropic glutamate receptor signaling. 19 Oct 2009
• Disruption of the axon initial segment cytoskeleton is a new mechanism for neuronal injury. 19 Oct 2009
• Activated actin-depolymerizing factor/cofilin sequesters phosphorylated microtubule-associated protein during the assembly of alzheimer-like neuritic cytoskeletal striations. 12 Oct 2009
• Cytoskeletal changes underlie estrogen's acute effects on synaptic transmission and plasticity. 12 Oct 2009
• Chronic exposure to anabolic androgenic steroids alters neuronal function in the mammalian forebrain via androgen receptor- and estrogen receptor-mediated mechanisms. 5 Oct 2009
• Chronic nicotine selectively enhances alpha4beta2* nicotinic acetylcholine receptors in the nigrostriatal dopamine pathway. 5 Oct 2009
• Ubiquitin-dependent lysosomal targeting of GABA(A) receptors regulates neuronal inhibition. 4 Oct 2009
• Role of GABA transporter 3 in GABAergic synaptic transmission at striatal output neurons. 29 Sep 2009
• TR(I)Pping towards treatment for ischemia. 29 Sep 2009
• Isoflurane inhibits cyclic adenosine monophosphate response element-binding protein phosphorylation and calmodulin translocation to the nucleus of SH-SY5Y cells. 29 Sep 2009

See a longer list of these articles.

Technical information about 'Neurons'

Definition: The basic cellular units of nervous tissue. Each neuron consists of a body, an axon, and dendrites. Their purpose is to receive, conduct, and transmit impulses in the NERVOUS SYSTEM.

Descriptor UI: D009474

Alternative terms: Neurons; Neuron; Nerve Cells; Cell, Nerve; Cells, Nerve; Nerve Cell;

Related Mesh Headings: Neural Conduction;

Allowable Qualifiers: classification; cytology; drug effects; enzymology; immunology; metabolism; microbiology; parasitology; pathology; physiology; radiation effects; radiography; radionuclide imaging; secretion; transplantation; ultrastructure; ultrasonography; chemistry; virology;

Tree Number: A08.663; A11.671;

Online Note: to search NERVE CELLS use NEUROGLIA & NEURONS 1966-74

History Note: NERVE CELLS was see under NEUROGLIA & NEURONS 1963-74

Technical Notes: do not use as a substitute or synonym for BRAIN /cytol