Neuropeptides - Administration & dosage
Research News and Information

Sunday, November 22, 2009

Activation of Akt/GSK-3beta signaling pathway is involved in intermedin(1-53) protection against myocardial apoptosis induced by ischemia/reperfusion.

30 Aug 2009 Intermedin (IMD) is a novel member of the calcitonin/calcitonin gene-related peptide family. We investigated the cardioprotective mechanism of IMD(1-53) in the in vivo rat model of myocardial ischemia/reperfusion (I/R) injury and in vitro primary ... Read more...

Central NMU signaling in body weight and energy balance regulation: evidence from NMUR2 deletion and chronic central NMU treatment in mice.

5 Jul 2009 To investigate the role of the central neuromedin U (NMU) signaling system in body weight and energy balance regulation, we examined the effects of long-term intracerebroventricular (icv) infusion of NMU in C57Bl/6 mice and in mice lacking the gene ... Read more...

Intranasal drug targeting of hypocretin-1 (orexin-A) to the central nervous system.

29 Jun 2009 The blood-brain barrier (BBB) limits the distribution of systemically administered therapeutics to the central nervous system (CNS). Intranasal delivery is a noninvasive method that targets drugs to the brain and spinal cord along olfactory and ... Read more...

Latest indexed articles for 'Neuropeptides - Administration & dosage'

These are the very latest articles for this heading:

• Activation of Akt/GSK-3beta signaling pathway is involved in intermedin(1-53) protection against myocardial apoptosis induced by ischemia/reperfusion. 30 Aug 2009
• Central NMU signaling in body weight and energy balance regulation: evidence from NMUR2 deletion and chronic central NMU treatment in mice. 5 Jul 2009
• Intranasal drug targeting of hypocretin-1 (orexin-A) to the central nervous system. 29 Jun 2009
• Intracerebroventricular administration of 26RFa produces an analgesic effect in the rat formalin test. 7 Jun 2009
• Orexin-stimulated MAP kinase cascades are activated through multiple G-protein signalling pathways in human H295R adrenocortical cells: diverse roles for orexins A and B. 19 May 2009
• Effects of intracerebroventricular administration of neuromedin U or neuromedin S in steers. 10 May 2009
• Daily intraparaventricular orexin-A treatment induces weight loss in rats. 31 Mar 2009
• Attenuation of kindled seizures by intranasal delivery of neuropeptide-loaded nanoparticles. 30 Mar 2009
• Neuropeptide S reinstates cocaine-seeking behavior and increases locomotor activity through corticotropin-releasing factor receptor 1 in mice. 30 Mar 2009
• Intracerebroventricular administration of N-acetylaspartic acid impairs antioxidant defenses and promotes protein oxidation in cerebral cortex of rats. 16 Mar 2009
• Reinstatement of cocaine seeking by hypocretin (orexin) in the ventral tegmental area: independence from the local corticotropin-releasing factor network. 26 Feb 2009
• Bioavailability of insect neuropeptides: the PK/PBAN family as a case study. 18 Feb 2009
• Central administration of somatostatin stimulates feeding behavior in chicks. 30 Jan 2009
• The orexigenic activity of the hypothalamic neuropeptide 26RFa is mediated by the neuropeptide Y and proopiomelanocortin neurons of the arcuate nucleus. 20 Jan 2009
• Role of the ventromedial hypothalamic orexin-1 receptors in regulation of gastric Acid secretion in conscious rats. 13 Jan 2009
• Neuromedin U enhances proliferation of ACTH-stimulated adrenocortical cells in the rat. 30 Dec 2008
• Intraventricular orexin-A improves arousal and early EEG entropy in rats after cardiac arrest. 14 Dec 2008
• Developing drugs that can cross the blood-brain barrier: applications to Alzheimer's disease. 8 Dec 2008
• The role of orexin A in the control of prolactin and growth hormone secretions in sheep--in vitro study. 29 Nov 2008
• Dipeptide "alaptide" prevented impairments in spontaneous behavior produced with trimethyltin in male rats. 29 Nov 2008

See a longer list of these articles.

Technical information about 'Neuropeptides'

Definition: Peptides released by NEURONS as intercellular messengers. Many neuropeptides are also hormones released by non-neuronal cells.

Registry Number: 0

Descriptor UI: D009479

Alternative terms: Neuropeptides; Neuropeptide;

Related Mesh Headings: Receptors, Neuropeptide;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D12.644.400; D12.776.641.650;

History Note: 87

Technical Notes: GEN or unspecified; prefer specifics