Neurotransmitter Agents
Research News and Information

Saturday, November 21, 2009

ELKS2alpha/CAST deletion selectively increases neurotransmitter release at inhibitory synapses.

27 Oct 2009 The presynaptic active zone is composed of a protein network that contains ELKS2alpha (a.k.a. CAST) as a central component. Here we demonstrate that in mice, deletion of ELKS2alpha caused a large increase in inhibitory, but not excitatory, ... Read more...

Neurotransmitters, receptors, and second messengers galore in 40 years.

12 Oct 2009 The past four decades have witnessed extraordinary advances in the molecular understanding of neurotransmitters, their receptors, and second messengers. This essay highlights a selected group of particular notable discoveries, emphasizing seminal ... Read more...

A protein interaction node at the neurotransmitter release site: domains of Aczonin/Piccolo, Bassoon, CAST, and rim converge on the N-terminal domain of Munc13-1.

5 Oct 2009 Multidomain scaffolding proteins organize the molecular machinery of neurotransmitter vesicle dynamics during synaptogenesis and synaptic activity. We find that domains of five active zone proteins converge on an interaction node that centers on the ... Read more...

Latest indexed articles for 'Neurotransmitter Agents'

These are the very latest articles for this heading:

• ELKS2alpha/CAST deletion selectively increases neurotransmitter release at inhibitory synapses. 27 Oct 2009
• Neurotransmitters, receptors, and second messengers galore in 40 years. 12 Oct 2009
• A protein interaction node at the neurotransmitter release site: domains of Aczonin/Piccolo, Bassoon, CAST, and rim converge on the N-terminal domain of Munc13-1. 5 Oct 2009
• Development of the Wireless Instantaneous Neurotransmitter Concentration System for intraoperative neurochemical monitoring using fast-scan cyclic voltammetry. 29 Sep 2009
• [Sexological problems in neurological disorders: neurosexology] 28 Sep 2009
• Vagal gustatory reflex circuits for intraoral food sorting behavior in the goldfish: cellular organization and neurotransmitters. 18 Sep 2009
• Comment on "The dynamic control of kiss-and-run and vesicular reuse probed with single nanoparticles". 16 Sep 2009
• Activity of Hb9 interneurons during fictive locomotion in mouse spinal cord. 14 Sep 2009
• Emerging principles and neural substrates underlying tonic sleep-state-dependent influences on respiratory motor activity. 10 Sep 2009
• Differential regulation of the central neural cardiorespiratory system by metabotropic neurotransmitters. 10 Sep 2009
• Neuroscience. Low-cost travel in neurons. 9 Sep 2009
• Asynchronous transmitter release from cholecystokinin-containing inhibitory interneurons is widespread and target-cell independent. 7 Sep 2009
• Differential but convergent functions of Ca2+ binding to synaptotagmin-1 C2 domains mediate neurotransmitter release. 2 Sep 2009
• An immunohistochemical approach to lungfish telencephalic organization. 31 Aug 2009
• Emerging drugs for major depressive disorder. 30 Aug 2009
• Secretin as a neurohypophysial factor regulating body water homeostasis. 30 Aug 2009
• [Amine neuromediators, their precursors, and oxidation products in the culture of Escherichia coli K-12] 30 Aug 2009
• Orexin neurons are necessary for the circadian control of REM sleep. 30 Aug 2009
• Regulation of DGK-theta. 30 Aug 2009
• Varenicline gets stronger warnings about psychiatric problems, vehicle crashes. 24 Aug 2009

See a longer list of these articles.

Technical information about 'Neurotransmitter Agents'

Definition: Substances used for their pharmacological actions on any aspect of neurotransmitter systems. Neurotransmitter agents include agonists, antagonists, degradation inhibitors, uptake inhibitors, depleters, precursors, and modulators of receptor function.

Registry Number: 0

Descriptor UI: D018377

Alternative terms: Neurotransmitter Agents; Agents, Neurotransmitter; Neuromodulators; Neuromodulator; Neurohormones; Neurotransmitters; Transmitter Substances, Nerve; Substances, Nerve Transmitter; Nerve Transmitter Substances; Neurotransmitter; Neurohumors; Neuroregulators; Neuroregulator;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D27.505.519.625; D27.505.696.577;

History Note: 1998; use explode 1995-1997

Technical Notes: general; prefer specifics