NF-kappa B
Research News and Information

Sunday, November 22, 2009

Both B1R and B2R act as intermediate signaling molecules in high glucose-induced stimulation of glutamate uptake in ARPE cells.

29 Nov 2009 Bradykinin (BK) is a potent modulator of biological processes in the retina, and retinal pigment epithelial cells (RPE) and the regulation of glutamate are believed to be important in the pathogenesis of diabetic retinopathy. However, the mechanism ... Read more...

Oxidized low density lipoprotein decreases Rankl-induced differentiation of osteoclasts by inhibition of Rankl signaling.

29 Nov 2009 The role of OxLDL in the generation and progression of atherosclerosis is well admitted. In addition, it is well known that atherosclerosis is often accompanied by perturbations in bone remodeling, resulting in osteoporosis. In the current studies, ... Read more...

Brain-derived neurotrophic factor protects cementoblasts from serum starvation-induced cell death.

29 Nov 2009 Our previous studies have shown that brain-derived neurotrophic factor (BDNF) enhances bone/cementum-related protein gene expression through the TrkB-c-Raf-ERK1/2-Elk-1 signaling pathway in cementoblasts, which play a critical role in the ... Read more...

Latest indexed articles for 'NF-kappa B'

These are the very latest articles for this heading:

• Both B1R and B2R act as intermediate signaling molecules in high glucose-induced stimulation of glutamate uptake in ARPE cells. 29 Nov 2009
• Oxidized low density lipoprotein decreases Rankl-induced differentiation of osteoclasts by inhibition of Rankl signaling. 29 Nov 2009
• Brain-derived neurotrophic factor protects cementoblasts from serum starvation-induced cell death. 29 Nov 2009
• Caffeic acid phenethyl ester, an active component of honeybee propolis attenuates osteoclastogenesis and bone resorption via the suppression of RANKL-induced NF-kappaB and NFAT activity. 29 Nov 2009
• Downregulation of p21-activated kinase-1 inhibits the growth of gastric cancer cells involving cyclin B1. 29 Nov 2009
• Fisetin, a natural flavonoid, targets chemoresistant human pancreatic cancer AsPC-1 cells through DR3-mediated inhibition of NF-kappaB. 13 Nov 2009
• Identification of a chemokine receptor profile characteristic for mediastinal large B-cell lymphoma. 13 Nov 2009
• Regulation of tissue homeostasis by NF-kappaB signalling: implications for inflammatory diseases. 30 Oct 2009
• The follicular versus marginal zone B lymphocyte cell fate decision. 30 Oct 2009
• NF-kappaB independent activation of a series of proinflammatory genes by hydrogen sulfide. 30 Oct 2009
• The IL-8 production by Streptococcal pyrogenic exotoxin B. 30 Oct 2009
• The effects of electroacupuncture on TH1/TH2 cytokine mRNA expression and mitogen-activated protein kinase signaling pathways in the splenic T cells of traumatized rats. 30 Oct 2009
• Curcumin sensitizes human colorectal cancer to capecitabine by modulation of cyclin D1, COX-2, MMP-9, VEGF and CXCR4 expression in an orthotopic mouse model. 30 Oct 2009
• CXCR7 is inducible by HTLV-1 Tax and promotes growth and survival of HTLV-1-infected T cells. 30 Oct 2009
• Regulation of HIV-1 transcription at 3% versus 21% oxygen concentration. 30 Oct 2009
• RAGE expression and NF-kappaB activation attenuated by extracellular domain of RAGE in human salivary gland cell line. 30 Oct 2009
• Cl-IB-MECA enhances TRAIL-induced apoptosis via the modulation of NF-kappaB signalling pathway in thyroid cancer cells. 30 Oct 2009
• Two mechanistically and temporally distinct NF-kappaB activation pathways in IL-1 signaling. 18 Oct 2009
• A noisy paracrine signal determines the cellular NF-kappaB response to lipopolysaccharide. 18 Oct 2009
• Gene expression profiling integrated into network modelling reveals heterogeneity in the mechanisms of BRCA1 tumorigenesis. 18 Oct 2009

See a longer list of these articles.

Technical information about 'NF-kappa B'

Definition: Ubiquitous, inducible, nuclear transcriptional activator that binds to enhancer elements in many different cell types and is activated by pathogenic stimuli. The NF-kappa B complex is a heterodimer composed of two DNA-binding subunits: NF-kappa B1 and relA.

Registry Number: 0

Descriptor UI: D016328

Alternative terms: NF-kappa B; kappa B Enhancer Binding Protein; NF-kappaB; NF kappaB; Transcription Factor NF-kB; Factor NF-kB, Transcription; NF-kB, Transcription Factor; Transcription Factor NF kB; NF-kB; NF kB; Immunoglobulin Enhancer-Binding Protein; Enhancer-Binding Protein, Immunoglobulin; Immunoglobulin Enhancer Binding Protein; Nuclear Factor kappa B; Ig-EBP-1; Ig EBP 1;

Related Mesh Headings: I-kappa B Proteins;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; agonists;

Tree Number: D12.776.260.600; D12.776.660.600; D12.776.930.600;

History Note: 91

Technical Notes: DF: NFKB