NG-Nitroarginine Methyl Ester - Antagonists & inhibitors
Research News and Information

Sunday, November 22, 2009

The nitric oxide (NO) donor molsidomine antagonizes scopolamine and L-NAME-induced performance deficits in a spatial memory task in the rat.

6 Jun 2009 Nitric oxide (NO) is considered as an intracellular messenger in the brain. Its involvement in learning and memory processes has been proposed. Compounds that inhibit NO synthase (NOS), the key synthesizing enzyme, may inhibit cognition, while NO ... Read more...

Vascular endothelial growth factor attenuates Nomega-nitro-L-arginine methyl ester-induced preeclampsia-like manifestations in rats.

29 Sep 2008 OBJECTIVES: To verify the hypothesis that vascular endothelial growth factor (VEGF) attenuates Nomega-Nitro-L-arginine Methyl Ester (L-NAME)-induced preeclampsia-like manifestations in rats. STUDY DESIGN: Forty pregnant Wistar rats were randomly ... Read more...

Analysis of L-NAME-dependent and -resistant responses to acetylcholine in the rat.

19 Nov 2007 The mechanism by which acetylcholine (ACh) decreases systemic arterial pressure and hindlimb vascular resistance was investigated in the anesthetized rat. ACh injections caused dose-dependent decreases in systemic arterial pressure and hindlimb ... Read more...

Latest indexed articles for 'NG-Nitroarginine Methyl Ester - Antagonists & inhibitors'

These are the very latest articles for this heading:

• The nitric oxide (NO) donor molsidomine antagonizes scopolamine and L-NAME-induced performance deficits in a spatial memory task in the rat. 6 Jun 2009
• Vascular endothelial growth factor attenuates Nomega-nitro-L-arginine methyl ester-induced preeclampsia-like manifestations in rats. 29 Sep 2008
• Analysis of L-NAME-dependent and -resistant responses to acetylcholine in the rat. 19 Nov 2007
• Antihypertensive mechanisms of chronic captopril or N-acetylcysteine treatment in L-NAME hypertensive rats. 29 Nov 2006
• Mechanisms underlying the relaxation induced by isokaempferide from Amburana cearensis in the guinea-pig isolated trachea. 5 Feb 2006
• Decreased microvascular nitric oxide-dependent vasodilation in postural tachycardia syndrome. 15 Oct 2005
• Effect of pioglitazone on L-NAME induced hypertension in diabetic rats. 13 Sep 2005
• Induces vasodilatation of rat mesenteric artery in vitro mainly by inhibiting receptor-mediated Ca(2+)-influx and Ca(2+)-release. 30 May 2005
• [Vasodilation effect of atropine on rat mesenteric artery] 29 Apr 2005
• Role of endogenous nitric oxide in endotoxin-induced alteration of hypoxic pulmonary vasoconstriction in mice. 16 Mar 2005
• Estrogen ameliorates Nomega-nitro-L-arginine methyl ester-induced blood pressure increment in male spontaneously hypertensive rats: the role of cGMP. 29 Dec 2004
• Evidence for the role of nitric oxide in nicotine-induced locomotor sensitization in mice. 7 Oct 2004
• Chronic nitric oxide synthase inhibition prevents new coronary capillary generation. 30 Aug 2004
• Effects of nitric oxide on aldosterone synthesis and nitric oxide synthase activity in glomerulosa cells from bovine adrenal gland. 30 May 2004
• Effects of phosphodiesterase V inhibition on nitric oxide-mediated relaxation responses in guinea pig trachea. 30 May 2004
• Functional study of the [Ca2+]i signaling pathway in aortas of L-NAME-hypertensive rats. 28 Feb 2004
• Vasoactive systems in L-NAME hypertension: the role of inducible nitric oxide synthase. 30 Dec 2003
• Relaxation of rat arteries by urocortin: effects of gender and diabetes. 30 May 2003
• Preventing L-NAME inhibitory effects on rat sexual behavior with hydralazine, isradipine or captopril co-treatment. 29 Apr 2003
• [Mechanism of nitric oxide-dependent skin vasodilation during febrilysis] 29 Apr 2003

See a longer list of these articles.

Technical information about 'NG-Nitroarginine Methyl Ester'

Definition: A non-selective inhibitor of nitric oxide synthase. It has been used experimentally to induce hypertension.

Registry Number: 50903-99-6

Descriptor UI: D019331

Alternative terms: NG-Nitroarginine Methyl Ester; Methyl Ester, NG-Nitroarginine; NG Nitroarginine Methyl Ester; N omega-Nitro-L-arginine Methyl Ester; N omega Nitro L arginine Methyl Ester; NG-Nitro-L-Arginine Methyl Ester; Methyl Ester, NG-Nitro-L-Arginine; NG Nitro L Arginine Methyl Ester; N(G)-Nitroarginine Methyl Ester; N(omega)-Nitro-L-arginine Methyl Ester; L-NAME; N(G)-Nitro-L-arginine Methyl Ester; NG-Nitroarginine Methyl Ester, L-Orn-Isomer, Monohydrochloride; NG-Nitroarginine Methyl Ester, D-Orn-Isomer; NG Nitroarginine Methyl Ester, D Orn Isomer;

Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Pharmacological Action: Enzyme Inhibitors;

Tree Number: D12.125.068.050.525; D12.125.095.104.525;

Online Note: use NG-NITROARGININE METHYL ESTER (NM) to search N(G)-NITROARGININE METHYL ESTER 1990-96

History Note: 97; was N(G)-NITROARGININE METHYL ESTER (NM) 1990-96

Technical Notes: DF: note short X ref