NG-Nitroarginine Methyl Ester
Research News and Information

Monday, November 23, 2009

Nitric oxide potentiation of locomotor activity in the spinal cord of the lamprey.

19 Oct 2009 To understand the intrinsic operation of spinal networks generating locomotion, we need to not only characterize the constituent neurons and their connectivity, but also determine the role of intrinsic modulation in shaping the final motor output. ... Read more...

Pulsating fluid flow modulates gene expression of proteins involved in Wnt signaling pathways in osteocytes.

29 Sep 2009 Strain-derived flow of interstitial fluid activates signal transduction pathways in osteocytes that regulate bone mechanical adaptation. Wnts are involved in this process, but whether mechanical loading modulates Wnt signaling in osteocytes is ... Read more...

eNOS uncoupling and endothelial dysfunction in aged vessels.

16 Sep 2009 Endothelial nitric oxide synthase (eNOS) uncoupling is a mechanism that leads to endothelial dysfunction. Previously, we reported that shear stress-induced release of nitric oxide in vessels of aged rats was significantly reduced and was accompanied ... Read more...

Latest indexed articles for 'NG-Nitroarginine Methyl Ester'

These are the very latest articles for this heading:

• Nitric oxide potentiation of locomotor activity in the spinal cord of the lamprey. 19 Oct 2009
• Pulsating fluid flow modulates gene expression of proteins involved in Wnt signaling pathways in osteocytes. 29 Sep 2009
• eNOS uncoupling and endothelial dysfunction in aged vessels. 16 Sep 2009
• Preoperative sCD40L levels predict risk of atrial fibrillation after off-pump coronary artery bypass graft surgery. 13 Sep 2009
• Angiotensin II enhances GABA(B) receptor-mediated responses and expression in nucleus tractus solitarii of rats. 9 Sep 2009
• Proinsulin C-peptide reduces diabetes-induced glomerular hyperfiltration via efferent arteriole dilation and inhibition of tubular sodium reabsorption. 7 Sep 2009
• Protective actions of estrogen on angiotensin II-induced hypertension: role of central nitric oxide. 2 Sep 2009
• Cross talk between kinin and angiotensin II receptors in mouse abdominal aorta. 30 Aug 2009
• Ex-vivo detection of neural events using THz BioMEMS. 30 Aug 2009
• H-Wave induces arteriolar vasodilation in rat striated muscle via nitric oxide-mediated mechanisms. 30 Aug 2009
• Trichinella: differential expression of angiogenic factors in macrophages stimulated with antigens from encapsulated and non-encapsulated species. 29 Aug 2009
• Reflex vasoconstriction in aged human skin increasingly relies on Rho kinase-dependent mechanisms during whole body cooling. 26 Aug 2009
• Antihypertensive and endothelium-dependent vasodilator effects of aqueous extract of Cistus ladaniferus. 24 Aug 2009
• Nitrite enhances RBC hypoxic ATP synthesis and the release of ATP into the vasculature: a new mechanism for nitrite-induced vasodilation. 19 Aug 2009
• The role of nitric oxide in the development of neurogenic pulmonary edema in spinal cord-injured rats: the effect of preventive interventions. 10 Aug 2009
• Phasic contractions of rat mesenteric lymphatics increase basal and phasic nitric oxide generation in vivo. 5 Aug 2009
• PPAR-gamma agonist rosiglitazone reverses increased cerebral venous hydraulic conductivity during hypertension. 5 Aug 2009
• Vascular endothelial growth factor receptor 2 controls blood pressure by regulating nitric oxide synthase expression. Aug 2009
• Vascular endothelial growth factor inhibitors and hypertension: a central role for the kidney and endothelial factors? Aug 2009
• Chronic antioxidant therapy fails to ameliorate hypertension: potential mechanisms behind. 30 Jul 2009

See a longer list of these articles.

Technical information about 'NG-Nitroarginine Methyl Ester'

Definition: A non-selective inhibitor of nitric oxide synthase. It has been used experimentally to induce hypertension.

Registry Number: 50903-99-6

Descriptor UI: D019331

Alternative terms: NG-Nitroarginine Methyl Ester; Methyl Ester, NG-Nitroarginine; NG Nitroarginine Methyl Ester; N omega-Nitro-L-arginine Methyl Ester; N omega Nitro L arginine Methyl Ester; NG-Nitro-L-Arginine Methyl Ester; Methyl Ester, NG-Nitro-L-Arginine; NG Nitro L Arginine Methyl Ester; N(G)-Nitroarginine Methyl Ester; N(omega)-Nitro-L-arginine Methyl Ester; L-NAME; N(G)-Nitro-L-arginine Methyl Ester; NG-Nitroarginine Methyl Ester, L-Orn-Isomer, Monohydrochloride; NG-Nitroarginine Methyl Ester, D-Orn-Isomer; NG Nitroarginine Methyl Ester, D Orn Isomer;

Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Pharmacological Action: Enzyme Inhibitors;

Tree Number: D12.125.068.050.525; D12.125.095.104.525;

Online Note: use NG-NITROARGININE METHYL ESTER (NM) to search N(G)-NITROARGININE METHYL ESTER 1990-96

History Note: 97; was N(G)-NITROARGININE METHYL ESTER (NM) 1990-96

Technical Notes: DF: note short X ref