Nicotine - Analysis
Research News and Information

Monday, November 23, 2009

Analysis of myosmine, cotinine and nicotine in human toenail, plasma and saliva.

30 Jul 2009 Myosmine is a minor tobacco alkaloid with widespread occurrence in the human diet. Myosmine is genotoxic in human cells and is readily nitrosated and peroxidated yielding reactive intermediates with carcinogenic potential. For biomonitoring of ... Read more...

Faster and stronger vascular "Biotube" graft fabrication in vivo using a novel nicotine-containing mold.

29 Jun 2009 To accelerate the fabrication of in vivo-tissue engineered autologous vascular prosthetic tissues, the "Biotube," a novel drug-coating mold was designed. The mold was prepared by impregnating nicotine as a model drug into a gelatinous matrix coated ... Read more...

[Chemicals added to cigarettes and their effects on tobacco dependence]

29 Jun 2009 This paper summarizes data on the factors involved in addiction and dependence to cigarettes. Nicotine has been intensively studied by the tobacco industry, for instance for its addictive effect at the lowest possible rates. The addition of ... Read more...

Latest indexed articles for 'Nicotine - Analysis'

These are the very latest articles for this heading:

• Less-toxic cigarette use may backfire. 19 Aug 2009
• Analysis of myosmine, cotinine and nicotine in human toenail, plasma and saliva. 30 Jul 2009
• Faster and stronger vascular "Biotube" graft fabrication in vivo using a novel nicotine-containing mold. 29 Jun 2009
• [Chemicals added to cigarettes and their effects on tobacco dependence] 29 Jun 2009
• Re: "Neonatal hair nicotine levels and fetal exposure to paternal smoking at home". 9 May 2009
• Nanostructure initiator mass spectrometry: tissue imaging and direct biofluid analysis. 13 Apr 2009
• Effects of timing and extent of smoking, type of cigarettes, and concomitant risk factors on the association between smoking and subclinical atherosclerosis. 7 Apr 2009
• Gas/particle partitioning of two acid-base active compounds in mainstream tobacco smoke: nicotine and ammonia. 6 Apr 2009
• Open questions on carcinogenesis of oral cancer: interaction between the environmental and genetic aspects. 30 Mar 2009
• Towards a quantitative SERS approach--online monitoring of analytes in a microfluidic system with isotope-edited internal standards. 30 Mar 2009
• Is house-dust nicotine a good surrogate for household smoking? 16 Mar 2009
• Method validation for measurement of hair nicotine level in nonsmokers. 27 Feb 2009
• Simultaneous quantification of nicotine, opioids, cocaine, and metabolites in human fetal postmortem brain by liquid chromatography tandem mass spectrometry. 19 Feb 2009
• Cigarette smoke extract induces activation of beta-catenin/TCF signaling through inhibiting GSK3beta in human alveolar epithelial cell line. 8 Feb 2009
• Nicotine contamination in particulate matter sampling. 7 Feb 2009
• Determination of nicotine in hair samples of pre-Columbian mummies. 4 Feb 2009
• Direct toxic effects of aqueous extract of cigarette smoke on cardiac myocytes at clinically relevant concentrations. 25 Jan 2009
• Smoking as a product of gene-environment interaction. 30 Dec 2008
• Comparison of environmental tobacco smoke (ETS) concentrations generated by an electrically heated cigarette smoking system and a conventional cigarette. 30 Dec 2008
• Approaches, challenges, and experience in assessing free nicotine. 30 Dec 2008

See a longer list of these articles.

Technical information about 'Nicotine'

Definition: Nicotine is highly toxic alkaloid. It is the prototypical agonist at nicotinic cholinergic receptors where it dramatically stimulates neurons and ultimately blocks synaptic transmission. Nicotine is also important medically because of its presence in tobacco smoke.

Chemical name: Pyridine, 3-(1-methyl-2-pyrrolidinyl)-, (S)-

Registry Number: 54-11-5

Descriptor UI: D009538

Alternative terms: Nicotine; Nicotine Tartrate; Tartrate, Nicotine; Nicotine Bitartrate; Bitartrate, Nicotine;

Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Pharmacological Action: Ganglionic Stimulants; Nicotinic Agonists;

Tree Number: D03.132.760.570; D03.383.725.518;

Technical Notes: /biosyn permitted if by plant