Nitric Oxide Donors - Pharmacology
Research News and Information

Monday, November 23, 2009

Nitric oxide potentiation of locomotor activity in the spinal cord of the lamprey.

19 Oct 2009 To understand the intrinsic operation of spinal networks generating locomotion, we need to not only characterize the constituent neurons and their connectivity, but also determine the role of intrinsic modulation in shaping the final motor output. ... Read more...

Shear stress regulates angiotensin type 1 receptor expression in endothelial cells.

15 Sep 2009 RATIONALE: Shear stress (SS) has an established role in atherosclerotic plaque localization, but how it exerts its protective effect is not fully understood. OBJECTIVE: To test the hypothesis that SS may downregulate angiotensin type 1 receptors ... Read more...

Effects of the cyclooxygenase inhibiting nitric oxide donator naproxcinod versus naproxen on systemic blood pressure in patients with osteoarthritis.

13 Sep 2009 Traditional nonsteroidal anti-inflammatory drugs are associated with the destabilization of blood pressure (BP) control, particularly in hypertensive patients treated with blockers of the renin-angiotensin system. To assess the potential impact of ... Read more...

Latest indexed articles for 'Nitric Oxide Donors - Pharmacology'

These are the very latest articles for this heading:

• Nitric oxide potentiation of locomotor activity in the spinal cord of the lamprey. 19 Oct 2009
• Shear stress regulates angiotensin type 1 receptor expression in endothelial cells. 15 Sep 2009
• Effects of the cyclooxygenase inhibiting nitric oxide donator naproxcinod versus naproxen on systemic blood pressure in patients with osteoarthritis. 13 Sep 2009
• Adjunct nitrous oxide normalizes vascular reactivity changes after hemorrhagic shock in mice under isoflurane anesthesia. 30 Aug 2009
• Sodium nitrite therapy attenuates the hypertensive effects of HBOC-201 via nitrite reduction. 25 Aug 2009
• Nitric oxide and pain: 'Something old, something new'. 19 Aug 2009
• Determinants of occurrence of aortic sclerosis in an aging population. 30 Jul 2009
• Interactions of the gaseous neuromodulators nitric oxide, carbon monoxide, and hydrogen sulfide in the salamander retina. 30 Jul 2009
• Intensity of GABA-evoked responses is modified by nitric oxide-active compounds in the subthalamic nucleus of the rat: a microiontophoretic study. 30 Jul 2009
• Radiosensitization of HT-29 cells and xenografts by the nitric oxide donor DETANONOate. 30 Jul 2009
• Valsartan improves endothelial dysfunction in hypertension: a randomized, double-blind study. 12 Jul 2009
• Functional localization of the nitric oxide/cGMP pathway in the salamander retina. 12 Jul 2009
• Nitric oxide and cGMP signal transduction positively regulates the motility of human neuronal precursor (NT2) cells. 12 Jul 2009
• Nitric oxide inhibits IFN regulatory factor 1 and nuclear factor-kappaB pathways in rhinovirus-infected epithelial cells. 7 Jul 2009
• Atrial natriuretic peptide and nitric oxide signaling antagonizes vasopressin-mediated water permeability in inner medullary collecting duct cells. 29 Jun 2009
• The effect of the nitric oxide donor sodium nitroprusside on glucose uptake in human primary skeletal muscle cells. 26 Jun 2009
• NO-glibenclamide derivatives: prototypes of a new class of nitric oxide-releasing anti-diabetic drugs. 25 Jun 2009
• Basal nitric oxide release attenuates cell migration of HeLa and endothelial cells. 23 Jun 2009
• Suppression of spreading depression-like events in locusts by inhibition of the NO/cGMP/PKG pathway. 22 Jun 2009
• Effects of propofol on responses of rat isolated renal arteriole to vasoactive agents. 19 Jun 2009

See a longer list of these articles.

Technical information about 'Nitric Oxide Donors'

Definition: A diverse group of agents, with unique chemical structures and biochemical requirements, which generate NITRIC OXIDE. These compounds have been used in the treatment of cardiovascular diseases and the management of acute myocardial infarction, acute and chronic congestive heart failure, and surgical control of blood pressure. (Adv Pharmacol 1995;34:361-81)

Registry Number: 0

Descriptor UI: D020030

Alternative terms: Nitric Oxide Donors; Donors, Nitric Oxide; Oxide Donors, Nitric;

Related Mesh Headings: Nitric Oxide;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D27.505.519.656; D27.505.954.411.590;

History Note: 99