Nitric Oxide Donors
Research News and Information

Sunday, November 22, 2009

Nitric oxide potentiation of locomotor activity in the spinal cord of the lamprey.

19 Oct 2009 To understand the intrinsic operation of spinal networks generating locomotion, we need to not only characterize the constituent neurons and their connectivity, but also determine the role of intrinsic modulation in shaping the final motor output. ... Read more...

Micelles for delivery of nitric oxide.

12 Oct 2009 We designed block copolymer pro-amphiphiles and amphiphiles for providing very long-term release of nitric oxide (NO). A block copolymer of N-acryloylmorpholine (AM, as a hydrophile) and N-acryloyl-2,5-dimethylpiperazine (AZd, as a hydrophilic ... Read more...

Shear stress regulates angiotensin type 1 receptor expression in endothelial cells.

15 Sep 2009 RATIONALE: Shear stress (SS) has an established role in atherosclerotic plaque localization, but how it exerts its protective effect is not fully understood. OBJECTIVE: To test the hypothesis that SS may downregulate angiotensin type 1 receptors ... Read more...

Latest indexed articles for 'Nitric Oxide Donors'

These are the very latest articles for this heading:

• Nitric oxide potentiation of locomotor activity in the spinal cord of the lamprey. 19 Oct 2009
• Micelles for delivery of nitric oxide. 12 Oct 2009
• Shear stress regulates angiotensin type 1 receptor expression in endothelial cells. 15 Sep 2009
• Effects of the cyclooxygenase inhibiting nitric oxide donator naproxcinod versus naproxen on systemic blood pressure in patients with osteoarthritis. 13 Sep 2009
• Adjunct nitrous oxide normalizes vascular reactivity changes after hemorrhagic shock in mice under isoflurane anesthesia. 30 Aug 2009
• Reflex vasoconstriction in aged human skin increasingly relies on Rho kinase-dependent mechanisms during whole body cooling. 26 Aug 2009
• Sodium nitrite therapy attenuates the hypertensive effects of HBOC-201 via nitrite reduction. 25 Aug 2009
• Nitric oxide regulates lung carcinoma cell anoikis through inhibition of ubiquitin-proteasomal degradation of caveolin-1. 23 Aug 2009
• Nitric oxide and pain: 'Something old, something new'. 19 Aug 2009
• Determinants of occurrence of aortic sclerosis in an aging population. 30 Jul 2009
• Randomised placebo-controlled trial of outpatient (at home) cervical ripening with isosorbide mononitrate (IMN) prior to induction of labour--clinical trial with analyses of efficacy and acceptability. The IMOP study. 30 Jul 2009
• Interactions of the gaseous neuromodulators nitric oxide, carbon monoxide, and hydrogen sulfide in the salamander retina. 30 Jul 2009
• Intensity of GABA-evoked responses is modified by nitric oxide-active compounds in the subthalamic nucleus of the rat: a microiontophoretic study. 30 Jul 2009
• Radiosensitization of HT-29 cells and xenografts by the nitric oxide donor DETANONOate. 30 Jul 2009
• Nitric oxide dilates rat retinal blood vessels by cyclooxygenase-dependent mechanisms. 20 Jul 2009
• Valsartan improves endothelial dysfunction in hypertension: a randomized, double-blind study. 12 Jul 2009
• Functional localization of the nitric oxide/cGMP pathway in the salamander retina. 12 Jul 2009
• Nitric oxide and cGMP signal transduction positively regulates the motility of human neuronal precursor (NT2) cells. 12 Jul 2009
• Nitric oxide inhibits IFN regulatory factor 1 and nuclear factor-kappaB pathways in rhinovirus-infected epithelial cells. 7 Jul 2009
• Atrial natriuretic peptide and nitric oxide signaling antagonizes vasopressin-mediated water permeability in inner medullary collecting duct cells. 29 Jun 2009

See a longer list of these articles.

Technical information about 'Nitric Oxide Donors'

Definition: A diverse group of agents, with unique chemical structures and biochemical requirements, which generate NITRIC OXIDE. These compounds have been used in the treatment of cardiovascular diseases and the management of acute myocardial infarction, acute and chronic congestive heart failure, and surgical control of blood pressure. (Adv Pharmacol 1995;34:361-81)

Registry Number: 0

Descriptor UI: D020030

Alternative terms: Nitric Oxide Donors; Donors, Nitric Oxide; Oxide Donors, Nitric;

Related Mesh Headings: Nitric Oxide;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D27.505.519.656; D27.505.954.411.590;

History Note: 99