Nitric Oxide Synthase Type III
Research News and Information

Sunday, November 22, 2009

Possible mechanisms involved in the discrepancy of hepatic and aortic endothelial nitric oxide synthases during the development of cirrhosis in rats.

25 Nov 2009 BACKGROUND/AIM: In cirrhosis, systemic nitric oxide (NO) overproduction and hepatic NO hypoproduction lead to arterial vasodilatation and portal hypertension. The mechanisms involved in these alterations in endothelial NO synthase (eNOS)-derived NO ... Read more...

Endothelial nitric oxide synthase negatively regulates hydrogen peroxide-stimulated AMP-activated protein kinase in endothelial cells.

23 Sep 2009 Hydrogen peroxide and other reactive oxygen species are intimately involved in endothelial cell signaling. In many cell types, the AMP-activated protein kinase (AMPK) has been implicated in the control of metabolic responses, but the role of ... Read more...

eNOS uncoupling and endothelial dysfunction in aged vessels.

16 Sep 2009 Endothelial nitric oxide synthase (eNOS) uncoupling is a mechanism that leads to endothelial dysfunction. Previously, we reported that shear stress-induced release of nitric oxide in vessels of aged rats was significantly reduced and was accompanied ... Read more...

Latest indexed articles for 'Nitric Oxide Synthase Type III'

These are the very latest articles for this heading:

• Possible mechanisms involved in the discrepancy of hepatic and aortic endothelial nitric oxide synthases during the development of cirrhosis in rats. 25 Nov 2009
• Endothelial nitric oxide synthase negatively regulates hydrogen peroxide-stimulated AMP-activated protein kinase in endothelial cells. 23 Sep 2009
• eNOS uncoupling and endothelial dysfunction in aged vessels. 16 Sep 2009
• Pyruvate-fortified cardioplegia evokes myocardial erythropoietin signaling in swine undergoing cardiopulmonary bypass. 16 Sep 2009
• Insulin-like growth factor binding protein-3 mediates vascular repair by enhancing nitric oxide generation. 15 Sep 2009
• Shear stress regulates angiotensin type 1 receptor expression in endothelial cells. 15 Sep 2009
• Effect of hypercholesterolemia on myocardial necrosis and apoptosis in the setting of ischemia-reperfusion. 13 Sep 2009
• Regulation of VASP phosphorylation in cardiac myocytes: differential regulation by cyclic nucleotides and modulation of protein expression in diabetic and hypertrophic heart. 2 Sep 2009
• Genetic determinants of cardiovascular disease: the renin-angiotensin-aldosterone system, paraoxonases, endothelin-1, nitric oxide synthase and adrenergic receptors. 30 Aug 2009
• Endothelial nitric oxide synthase is up-regulated in the umbilical cord in pregnancies complicated with intrauterine growth retardation. 30 Aug 2009
• [Hyperdynamic circulation in patients with liver cirrhosis and portal hypertension] 30 Aug 2009
• Lactosylceramide causes endothelial dysfunction in porcine coronary arteries and human coronary artery endothelial cells. 30 Aug 2009
• Ceramide mediates inhibition of the AKT/eNOS signaling pathway by palmitate in human vascular endothelial cells. 30 Aug 2009
• Possible neuroprotective effect of brimonidine in a mouse model of ischaemic optic neuropathy. 30 Aug 2009
• Antenatal corticosteroids increase fetal, but not postnatal, pulmonary blood flow in sheep. 30 Aug 2009
• Nitrite as regulator of hypoxic signaling in mammalian physiology. 30 Aug 2009
• Insulin inhibits myocardial ischemia-induced apoptosis and alleviates chronic adverse changes in post-ischemic cardiac structure and function. 30 Aug 2009
• Role of LOX-1 in monocyte adhesion-triggered redox, Akt/eNOS and Ca2+ signaling pathways in endothelial cells. 30 Aug 2009
• Pericyte contraction induced by oxidative-nitrative stress impairs capillary reflow despite successful opening of an occluded cerebral artery. 28 Aug 2009
• Nitric oxide and pathogenic mechanisms involved in the development of vascular diseases. 27 Aug 2009

See a longer list of these articles.

Technical information about 'Nitric Oxide Synthase Type III'

Definition: A CALCIUM-dependent, constitutively-expressed form of nitric acid synthase found primarily in ENDOTHELIAL CELLS.

Registry Number: EC 1.14.13.39

Descriptor UI: D052250

Alternative terms: Nitric Oxide Synthase Type III; Nitric Oxide Synthase, Type III; Endothelial Nitric Oxide Synthase; ENOS Enzyme; ECNOS Enzyme; Endothelial Constitutive Nitric Oxide Synthase;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications;

Tree Number: D08.811.682.664.500.772.750;

History Note: 2006(1998)