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Nociceptors
Research News and Information
Definition of 'Nociceptors'Peripheral AFFERENT NEURONS which are sensitive to injuries or pain, usually caused by extreme thermal exposures, mechanical forces, or other noxious stimuli. Their cell bodies reside in the DORSAL ROOT GANGLIA. Their peripheral terminals (NERVE ENDINGS) innervate target tissues and transduce noxious stimuli via axons to the CENTRAL NERVOUS SYSTEM. Common names: Nociceptors; Nociceptor; Pain Receptors; Pain Receptor; Receptors, Pain; Nociceptive Neurons; Neuron, Nociceptive; Neurons, Nociceptive; Nociceptive Neuron |
Sunday, November 22, 2009
Kinematic and neurophysiological models: future applications in neurorehabilitation.
30 Oct 2009 
This paper emphasizes the importance of developing kinematic and neurophysiological methods for evaluating motor and functional recovery in the field of neurorehabilitation. From a review of the literature, it is concluded that optoelectronic motion ... Read more...
19 Oct 2009 Peripheral tissue injury is associated with changes in protein expression in sensory neurons that may contribute to abnormal nociceptive processing. We used cultured dorsal root ganglion (DRG) neurons as a model of axotomized neurons to investigate ... Read more...
19 Oct 2009 The Mas-related G-protein-coupled receptor D (Mrgprd) marks a distinct subset of sensory neurons that transmit polymodal nociceptive information from the skin epidermis to the substantia gelatinosa (SG, lamina II) of the spinal cord. Moreover, ... Read more...
Latest indexed articles for 'Nociceptors'
These are the very latest articles for this heading:
- Kinematic and neurophysiological models: future applications in neurorehabilitation. 30 Oct 2009
- Proteomic analysis uncovers novel actions of the neurosecretory protein VGF in nociceptive processing. 19 Oct 2009
- Mrgprd-expressing polymodal nociceptive neurons innervate most known classes of substantia gelatinosa neurons. 19 Oct 2009
- Cellular and molecular mechanisms of pain. 14 Oct 2009
- Inhibitor kappaB Kinase beta deficiency in primary nociceptive neurons increases TRP channel sensitivity. 12 Oct 2009
- Differences in post-inflammatory hypersensitivity between splanchnic and pelvic afferents: mechanisms and implications for human disease.
29 Sep 2009 - Psychophysical and functional imaging evidence supporting the presence of central sensitization in a cohort of osteoarthritis patients. 13 Sep 2009
- Protein kinase D isoforms are expressed in rat and mouse primary sensory neurons and are activated by agonists of protease-activated receptor 2. 8 Sep 2009
- Recombinant adeno-associated virus serotype 6 (rAAV2/6)-mediated gene transfer to nociceptive neurons through different routes of delivery. 6 Sep 2009
- Metalloproteinase MT5-MMP is an essential modulator of neuro-immune interactions in thermal pain stimulation. 2 Sep 2009
- Central sensitization: a generator of pain hypersensitivity by central neural plasticity. 30 Aug 2009
- Intradermal administration of magnesium sulphate and magnesium chloride produces hypesthesia to mechanical but hyperalgesia to heat stimuli in humans. 26 Aug 2009
- Nitric oxide and pain: 'Something old, something new'. 19 Aug 2009
- Expression of TRPV4 in the stimulated rat oral mucous membrane--nociceptive mechanisms of lingual conical papillae. 30 Jul 2009
- Dysautonomia after severe traumatic brain injury: evidence of persisting overresponsiveness to afferent stimuli. 30 Jul 2009
- Rat dorsal horn nociceptive-specific neurons are more sensitive than wide dynamic range neurons to depression by immobilizing doses of volatile anesthetics: an effect partially reversed by the opioid receptor antagonist naloxone.
30 Jul 2009 - Molecular mechanisms of lipoic acid modulation of T-type calcium channels in pain pathway. 27 Jul 2009
- Blink reflexes in chronic tension-type headache patients and healthy controls. 22 Jul 2009
- Spinal ERK activation via NO-cGMP pathway contributes to nociceptive behavior induced by morphine-3-glucuronide. 5 Jul 2009
- Multimodal analgesia for chronic pain: rationale and future directions. 29 Jun 2009
See a longer list of these articles.
Technical information about 'Nociceptors'
Definition: Peripheral AFFERENT NEURONS which are sensitive to injuries or pain, usually caused by extreme thermal exposures, mechanical forces, or other noxious stimuli. Their cell bodies reside in the DORSAL ROOT GANGLIA. Their peripheral terminals (NERVE ENDINGS) innervate target tissues and transduce noxious stimuli via axons to the CENTRAL NERVOUS SYSTEM.
Descriptor UI: D009619
Alternative terms: Nociceptors; Nociceptor; Pain Receptors; Pain Receptor; Receptors, Pain; Nociceptive Neurons; Neuron, Nociceptive; Neurons, Nociceptive; Nociceptive Neuron;
Allowable Qualifiers: classification; cytology; drug effects; enzymology; immunology; metabolism; microbiology; parasitology; pathology; physiology; radiation effects; radiography; radionuclide imaging; secretion; transplantation; ultrastructure; ultrasonography; chemistry; virology;
Tree Number: A08.663.650.915.875; A08.800.950.875; A11.671.650.915.875;
History Note: 78
Technical Notes: DF: NOCICEPT