Nootropic Agents - Isolation & purification
Research News and Information

Sunday, November 22, 2009

Cognitive-enhancing activity of loganin isolated from Cornus officinalis in scopolamine-induced amnesic mice.

25 May 2009 We examined anti-amnesic activity of the methanolic extract of Cornus officinalis fruits (COT) and a major constituent, loganin using scopolamine-induced (1 mg/kg body weight, s.c.) amnesic mice with both passive avoidance and the Morris water maze ... Read more...

Effect of triterpenoid saponins from Bacopa monniera on scopolamine-induced memory impairment in mice.

10 Feb 2009 Three new saponins, bacopasides IX-XI (1- 3), together with their known analogues bacopaside I (4), bacopaside II (5), bacopasaponsin C (6), and bacopasaponsin D (7), were isolated from the whole plant of Bacopa monniera. Compounds 3, 4, and 6 ... Read more...

Nobiletin, a citrus flavonoid with neurotrophic action, augments protein kinase A-mediated phosphorylation of the AMPA receptor subunit, GluR1, and the postsynaptic receptor response to glutamate in murine hippocampus.

30 Sep 2007 Nobiletin isolated from citrus peels prevents bulbectomy- and amyloid-beta protein-induced memory impairment in rodents. In the present study, using combined methods of biochemistry and electrophysiology, we examined the effects of nobiletin on ... Read more...

Latest indexed articles for 'Nootropic Agents - Isolation & purification'

These are the very latest articles for this heading:

• Cognitive-enhancing activity of loganin isolated from Cornus officinalis in scopolamine-induced amnesic mice. 25 May 2009
• Effect of triterpenoid saponins from Bacopa monniera on scopolamine-induced memory impairment in mice. 10 Feb 2009
• Nobiletin, a citrus flavonoid with neurotrophic action, augments protein kinase A-mediated phosphorylation of the AMPA receptor subunit, GluR1, and the postsynaptic receptor response to glutamate in murine hippocampus. 30 Sep 2007
• [The localization of galanthamine in vegetative organ of Lycoris aurea Herb] 29 Sep 2007
• Gugulipid, an extract of Commiphora whighitii with lipid-lowering properties, has protective effects against streptozotocin-induced memory deficits in mice. Apr 2007
• Multifunctional drugs with different CNS targets for neuropsychiatric disorders. 16 Oct 2006
• Neuropharmacological evaluation of Ginkgo biloba phytosomes in rodents. 29 Sep 2006
• Method for enantiomeric purity of a quinuclidine candidate drug by capillary electrophoresis. 30 Jul 2006
• [Nootropic mechanisms of ginsenoside Rg1--influence on neuronal plasticity and neurogenesis] 29 Apr 2005
• Effects of Yukmijihwang-tang derivatives (YMJd), a memory enhancing herbal extract, on the gene-expression profile in the rat hippocampus. 30 Dec 2004
• Cognitive improving and cerebral protective effects of acylated oligosaccharides in Polygala tenuifolia. 29 Jun 2004
• Galanthamine from snowdrop--the development of a modern drug against Alzheimer's disease from local Caucasian knowledge. 30 May 2004
• Ginseng: potential for the enhancement of cognitive performance and mood. 30 May 2003
• A comparative study in rodents of standardized extracts of Bacopa monniera and Ginkgo biloba: anticholinesterase and cognitive enhancing activities. 30 Oct 2002
• Enantiomeric resolution of galanthamine and related drugs used in anti-Alzheimer therapy by means of capillary zone electrophoresis employing derivatized cyclodextrin selectors. 7 Jul 1999
• Candidates for cognitive enhancer extracted from medicinal plants: paeoniflorin and tetramethylpyrazine. 30 Jan 1997
• [Identification in the rat brain of cyclo-prolylglycine, a novel endogenous peptide with nootropic activity] 29 Sep 1996
• Neurotropic components from star anise (Illicium verum Hook. fil.) 29 Sep 1996

See a longer list of these articles.

Technical information about 'Nootropic Agents'

Definition: Drugs used to specifically facilitate learning or memory, particularly to prevent the cognitive deficits associated with dementias. These drugs act by a variety of mechanisms. While no potent nootropic drugs have yet been accepted for general use, several are being actively investigated.

Registry Number: 0

Descriptor UI: D018697

Alternative terms: Nootropic Agents; Agents, Nootropic; Nootropics; Cognitive Enhancers; Enhancers, Cognitive; Nootropic Drugs; Drugs, Nootropic;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D27.505.954.427.637;

Online Note: use PSYCHOTROPIC DRUGS to search NOOTROPIC DRUGS 1990-94

History Note: 95; NOOTRPIC DRUGS was see PSYCHOTROPIC DRUGS 1990-94

Technical Notes: CNS agents; from Greek nous, mind; GEN or unspecified: prefer specifics