Norepinephrine - Metabolism
Research News and Information

Saturday, November 21, 2009

Retrograde viral vector-mediated inhibition of pontospinal noradrenergic neurons causes hyperalgesia in rats.

12 Oct 2009 Pontospinal noradrenergic neurons form a component of an endogenous analgesic system and represent a potential therapeutic target. We tested the principle that genetic manipulation of their excitability can alter nociception using an adenoviral ... Read more...

Development of the Wireless Instantaneous Neurotransmitter Concentration System for intraoperative neurochemical monitoring using fast-scan cyclic voltammetry.

29 Sep 2009 OBJECT: Emerging evidence supports the hypothesis that modulation of specific central neuronal systems contributes to the clinical efficacy of deep brain stimulation (DBS) and motor cortex stimulation (MCS). Real-time monitoring of the neurochemical ... Read more...

BMP signaling regulates sympathetic nervous system development through Smad4-dependent and -independent pathways.

28 Sep 2009 Induction of the sympathetic nervous system (SNS) from its neural crest (NC) precursors is dependent on BMP signaling from the dorsal aorta. To determine the roles of BMP signaling and the pathways involved in SNS development, we conditionally ... Read more...

Latest indexed articles for 'Norepinephrine - Metabolism'

These are the very latest articles for this heading:

• Retrograde viral vector-mediated inhibition of pontospinal noradrenergic neurons causes hyperalgesia in rats. 12 Oct 2009
• Development of the Wireless Instantaneous Neurotransmitter Concentration System for intraoperative neurochemical monitoring using fast-scan cyclic voltammetry. 29 Sep 2009
• BMP signaling regulates sympathetic nervous system development through Smad4-dependent and -independent pathways. 28 Sep 2009
• 1- or 3-(3-Amino-2-hydroxy-1-phenyl propyl)-1,3-dihydro-2H-benzimidazol-2-ones: potent, selective, and orally efficacious norepinephrine reuptake inhibitors. 22 Sep 2009
• Parallel preoptic pathways for thermoregulation. 21 Sep 2009
• The use of viral gene transfer in studies of brainstem noradrenergic and serotonergic neurons. 10 Sep 2009
• Vasopressin is a major vasoconstrictor involved in hindlimb vascular responses to stimulation of adenosine A(1) receptors in the nucleus of the solitary tract. 9 Sep 2009
• Molecular recognition of physiological substrate noradrenaline by the adrenaline-synthesizing enzyme PNMT and factors influencing its methyltransferase activity. 25 Aug 2009
• Renal sympathetic-nerve ablation for uncontrolled hypertension. 25 Aug 2009
• Stress, genotype and norepinephrine in the prediction of mouse behavior using reinforcement learning. 14 Aug 2009
• Gene expression analyses of neurons, astrocytes, and oligodendrocytes isolated by laser capture microdissection from human brain: detrimental effects of laboratory humidity. 13 Aug 2009
• Neurotransmitter receptor imbalances in motor cortex and basal ganglia in hepatic encephalopathy. Aug 2009
• TCEP treatment reduces proteolytic activity of BoNT/B in human neuronal SHSY-5Y cells. 30 Jul 2009
• Nicotinic receptor-associated modulation of stimulatory and inhibitory neurotransmitters in NNK-induced adenocarcinoma of the lungs and pancreas. 30 Jul 2009
• Differential fading of inhibitory and excitatory B2 bradykinin receptor responses in rat sympathetic neurons: a role for protein kinase C. 23 Jul 2009
• Age-dependent changes in noradrenergic locus coeruleus system in wild-type and APP23 transgenic mice. 21 Jul 2009
• The novel nicotinic receptor antagonist, N,N'-dodecane-1,12-diyl-bis-3-picolinium dibromide (bPiDDB), inhibits nicotine-evoked [(3)H]norepinephrine overflow from rat hippocampal slices. 21 Jul 2009
• Absence of gp130 in dopamine beta-hydroxylase-expressing neurons leads to autonomic imbalance and increased reperfusion arrhythmias. 8 Jul 2009
• Acute cold exposure-induced down-regulation of CIDEA, cell death-inducing DNA fragmentation factor-alpha-like effector A, in rat interscapular brown adipose tissue by sympathetically activated beta3-adrenoreceptors. Jul 2009
• Estradiol increases catecholamine levels in the hypothalamus of ovariectomized rats during the dark-phase. 30 Jun 2009

See a longer list of these articles.

Technical information about 'Norepinephrine'

Definition: Precursor of epinephrine that is secreted by the adrenal medulla and is a widespread central and autonomic neurotransmitter. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceruleus. It is also found in plants and is used pharmacologically as a sympathomimetic.

Chemical name: 1,2-Benzenediol, 4-(2-amino-1-hydroxyethyl)-, (R)-

Registry Number: 51-41-2

Descriptor UI: D009638

Alternative terms: Norepinephrine; Noradrenaline; Levarterenol; Levonorepinephrine; Norepinephrine, (+,-)-Isomer; Norepinephrine Hydrochloride, (+,-)-Isomer; Norepinephrine l-Tartrate (1:1), (+,-)-Isomer; Arterenol; Aventis Brand of Norepinephrine Hydrochloride; Levonor; Levophed; Abbott Brand of Levophed Bitartrate; Levophed Bitartrate; Bitartrate, Levophed; Norepinephrin d-Tartrate (1:1); Norepinephrine Bitartrate; Bitartrate, Norepinephrine; Norepinephrine l-Tartrate (1:1); Noradrenaline Bitartrate; Bitartrate, Noradrenaline; Norepinephrine Hydrochloride; Hydrochloride, Norepinephrine; Norepinephrine l-Tartrate (1:1), Monohydrate; Norepinephrine l-Tartrate (1:1), Monohydrate, (+)-Isomer; Norepinephrine l-Tartrate (1:2); Norepinephrine l-Tartrate, (+)-Isomer; Norepinephrine, (+)-Isomer; Noradrénaline tartrate renaudin; renaudin, Noradrénaline tartrate; tartrate renaudin, Noradrénaline; Renaudin Brand of Norepinephrine Bitartrate; Norepinephrine Hydrochloride, (+)-Isomer;

Related Mesh Headings: Receptors, Adrenergic;

Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Pharmacological Action: Adrenergic alpha-Agonists; Sympathomimetics; Vasoconstrictor Agents;

Tree Number: D02.033.100.291.502; D02.092.063.480; D02.092.211.215.311.560; D02.092.311.461.484;

Online Note: use NOREPINEPHRINE to search ARTERENOL 1974-93

History Note: ARTERENOL was see NOREPINEPHRINE 1974-93; LEVONOREPINEPHRINE was heading 1963-65