Nuclear Proteins - Genetics
Research News and Information

Saturday, November 21, 2009

Expression of RIZ1 protein (Retinoblastoma-interacting zinc-finger protein 1) in prostate cancer epithelial cells changes with cancer grade progression and is modulated in vitro by DHT and E2.

29 Nov 2009 The nuclear protein methyl-transferase Retinoblastoma-interacting zinc-finger protein 1 (RIZ1) is considered to be a downstream effector of estrogen action in target tissues. Silencing of RIZ1 expression is common in many tumors. We analyzed RIZ1 ... Read more...

p8/nupr1 regulates DNA-repair activity after double-strand gamma irradiation-induced DNA damage.

29 Nov 2009 The stress protein p8 is a small, highly basic, unfolded, and multifunctional protein. We have previously shown that most of its functions are exerted through interactions with other proteins, whose activities are thereby enhanced or repressed. In ... Read more...

p73 G4C14-to-A4T14 polymorphism and risk of second primary malignancy after index squamous cell carcinoma of head and neck.

29 Nov 2009 P73 plays an important role in modulating cell-cycle control, inducing apoptosis, and inhibiting cell growth. A novel noncoding p73 G4C14-to-A4T14 exon 2 polymorphism was associated with risk of squamous cell carcinoma of the head and neck (SCCHN). ... Read more...

Latest indexed articles for 'Nuclear Proteins - Genetics'

These are the very latest articles for this heading:

• Expression of RIZ1 protein (Retinoblastoma-interacting zinc-finger protein 1) in prostate cancer epithelial cells changes with cancer grade progression and is modulated in vitro by DHT and E2. 29 Nov 2009
• p8/nupr1 regulates DNA-repair activity after double-strand gamma irradiation-induced DNA damage. 29 Nov 2009
• p73 G4C14-to-A4T14 polymorphism and risk of second primary malignancy after index squamous cell carcinoma of head and neck. 29 Nov 2009
• Common germline polymorphisms in COMT, CYP19A1, ESR1, PGR, SULT1E1 and STS and survival after a diagnosis of breast cancer. 29 Nov 2009
• The mechanisms underlying MMR deficiency in immunodeficiency-related non-Hodgkin lymphomas are different from those in other sporadic microsatellite instable neoplasms. 13 Nov 2009
• Necdin: a multi functional protein with potential tumor suppressor role? 30 Oct 2009
• The suppression of MAD1 by AKT-mediated phosphorylation activates MAD1 target genes transcription. 30 Oct 2009
• Immunohistochemistry as first-line screening for detecting colorectal cancer patients at risk for hereditary nonpolyposis colorectal cancer syndrome: a 2-antibody panel may be as predictive as a 4-antibody panel. 30 Oct 2009
• Genetic and molecular insights into the development and evolution of sexual dimorphism. 30 Oct 2009
• Sun proteins enlighten nuclear movement in development. 27 Oct 2009
• Risk of pancreatic cancer in families with Lynch syndrome. 26 Oct 2009
• Analysis of the dual function of the ESCRT-III protein Snf7 in endocytic trafficking and in gene expression. 21 Oct 2009
• Grafting neural precursor cells promotes functional recovery in an SCA1 mouse model. 19 Oct 2009
• Differential regulation of telomere and centromere cohesion by the Scc3 homologues SA1 and SA2, respectively, in human cells. 10 Oct 2009
• C-terminal sequences of hsp70 and hsp90 as non-specific anchors for tetratricopeptide repeat (TPR) proteins. 10 Oct 2009
• Tudor staphylococcal nuclease is an evolutionarily conserved component of the programmed cell death degradome. 9 Oct 2009
• Human genetics: Hit or miss? 6 Oct 2009
• Glucocorticoid regulation of the circadian clock modulates glucose homeostasis. 3 Oct 2009
• Nbs1 flexibly tethers Ctp1 and Mre11-Rad50 to coordinate DNA double-strand break processing and repair. 30 Sep 2009
• MycN is a transcriptional regulator of livin in neuroblastoma. 29 Sep 2009

See a longer list of these articles.

Technical information about 'Nuclear Proteins'

Definition: Proteins found in the nucleus of a cell. Do not confuse with NUCLEOPROTEINS which are proteins conjugated with nucleic acids, that are not necessarily present in the nucleus.

Registry Number: 0

Descriptor UI: D009687

Alternative terms: Nuclear Proteins; Proteins, Nuclear; Nucleolar Proteins; Proteins, Nucleolar; Nuclear Protein; Protein, Nuclear;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; agonists;

Tree Number: D12.776.660;

History Note: 88

Technical Notes: proteins in the cell nucleus: do not confuse with NUCLEOPROTEINS (proteins conjugated with nucleic acids)