Nucleus Accumbens - Metabolism
Research News and Information

Sunday, November 22, 2009

Differential corticosteroid receptor regulation of mesoaccumbens dopamine efflux during the peak and nadir of the circadian rhythm: a molecular equilibrium in the midbrain?

30 Oct 2009 Corticosteroid receptor modulation of mesoaccumbens dopamine neurotransmission is believed to be a key neurobiological mechanism mediating the effects of stress in addiction. Importantly, nucleus accumbens (NAc) subregions (core and shell) are ... Read more...

Regulation of dynamin 2 and G protein-coupled receptor kinase 2 in rat nucleus accumbens during acute and repeated cocaine administration.

29 Sep 2009 Exposure to cocaine causes many neuroadaptations including alterations in several neurotransmitter receptors and transporters. This study investigated potential mechanisms of cocaine-induced receptor and transporter regulation by measuring levels of ... Read more...

Dopaminergic response to graded dopamine concentration elicited by four amphetamine doses.

30 Aug 2009 We studied the metabolic responses to different DA concentrations elicited by four doses of D-amphetamine (AMPH, 0, 0.25, 0.5, 1.0, or 3.0 mg/kg). We compared the degree of DA release (via microdialysis) with striatal cAMP activity and whole brain ... Read more...

Latest indexed articles for 'Nucleus Accumbens - Metabolism'

These are the very latest articles for this heading:

• Differential corticosteroid receptor regulation of mesoaccumbens dopamine efflux during the peak and nadir of the circadian rhythm: a molecular equilibrium in the midbrain? 30 Oct 2009
• Regulation of dynamin 2 and G protein-coupled receptor kinase 2 in rat nucleus accumbens during acute and repeated cocaine administration. 29 Sep 2009
• Dopaminergic response to graded dopamine concentration elicited by four amphetamine doses. 30 Aug 2009
• In vivo evidence that constitutive activity of serotonin2C receptors in the medial prefrontal cortex participates in the control of dopamine release in the rat nucleus accumbens: differential effects of inverse agonist versus antagonist. 20 Aug 2009
• Nucleus accumbens neurons exhibit synaptic scaling that is occluded by repeated dopamine pre-exposure. 5 Aug 2009
• Inactivating the activated: identifying functions of specific neural networks. 30 Jul 2009
• P2 receptor-mediated stimulation of the PI3-K/Akt-pathway in vivo. 30 Jul 2009
• Interoceptive effects of alcohol require mGlu5 receptor activity in the nucleus accumbens. 27 Jul 2009
• Chronic ethanol treatment potentiates ethanol-induced increases in interstitial nucleus accumbens endocannabinoid levels in rats. 21 Jul 2009
• Antidepressant treatment facilitates dopamine release and drug seeking behavior in a genetic animal model of depression. 13 Jul 2009
• Neuropeptide Y infusion into the shell region of the rat nucleus accumbens increases extracellular levels of dopamine. 13 Jul 2009
• Distinct opioid circuits determine the palatability and the desirability of rewarding events. 11 Jul 2009
• Cocaine-evoked synaptic plasticity: persistence in the VTA triggers adaptations in the NAc. 11 Jul 2009
• Role for GABA agonists in the nucleus accumbens in regulating morphine self-administration. 8 Jul 2009
• Binge drinking upregulates accumbens mGluR5-Homer2-PI3K signaling: functional implications for alcoholism. 6 Jul 2009
• Up-regulation of cocaine- and amphetamine-regulated transcript (CART) in the rat nucleus accumbens after repeated electroconvulsive shock. Jul 2009
• Long-term effects of neonatal handling on mu-opioid receptor levels in the brain of the offspring. 29 Jun 2009
• Gustatory and homeostatic functions of the rodent parabrachial nucleus. 29 Jun 2009
• Plasticity of addiction: a mesolimbic dopamine short-circuit? 29 Jun 2009
• Extended daily access to cocaine results in distinct alterations in Homer 1b/c and NMDA receptor subunit expression within the medial prefrontal cortex. 29 Jun 2009

See a longer list of these articles.

Technical information about 'Nucleus Accumbens'

Definition: Collection of pleomorphic cells in the caudal part of the anterior horn of the lateral ventricle, in the region of the olfactory tubercle, lying between the head of the caudate nucleus and the anterior perforated substance. It is part of the so-called ventral striatum, a composite structure considered part of the basal ganglia.

Descriptor UI: D009714

Alternative terms: Nucleus Accumbens; Accumbens, Nucleus;

Allowable Qualifiers: abnormalities; anatomy & histology; blood supply; cytology; drug effects; embryology; enzymology; growth & development; immunology; injuries; metabolism; microbiology; parasitology; pathology; physiology; physiopathology; radiation effects; radiography; radionuclide imaging; secretion; surgery; transplantation; ultrastructure; ultrasonography; chemistry; virology;

Tree Number: A08.186.211.730.885.287.249.683;

History Note: 91(78); was see under SEPTAL NUCLEI 1978-90