 |
Octanoic Acids - Pharmacology
Research News and Information
Sunday, November 22, 2009
DCP-LA stimulates AMPA receptor exocytosis through CaMKII activation due to PP-1 inhibition.
29 Sep 2009 
The linoleic acid derivative 8-[2-(2-pentyl-cyclopropylmethyl)-cyclopropyl]-octanoic acid (DCP-LA) activated Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) by inhibiting protein phosphatase-1 (PP-1). DCP-LA induced a transient huge ... Read more...
Perfluorooctanoic acid stimulated mitochondrial biogenesis and gene transcription in rats.
14 Jul 2009 Perfluorooctanoic acid (PFOA), used in the production of non-stick surface compounds, exhibits a worldwide distribution in the serum of humans and wildlife. In rodents PFOA transactivates PPARalpha and PPARgamma nuclear receptors and increases ... Read more...
15 Jun 2009 An analysis of group IVA (GIVA) phospholipase A(2) (PLA(2)) inhibitor binding was conducted using a combination of deuterium exchange mass spectrometry (DXMS) and molecular dynamics (MD). Models of the GIVA PLA(2) inhibitors pyrrophenone and the ... Read more...
Latest indexed articles for 'Octanoic Acids - Pharmacology'
These are the very latest articles for this heading:
- DCP-LA stimulates AMPA receptor exocytosis through CaMKII activation due to PP-1 inhibition. 29 Sep 2009
- Perfluorooctanoic acid stimulated mitochondrial biogenesis and gene transcription in rats. 14 Jul 2009
- Location of inhibitors bound to group IVA phospholipase A2 determined by molecular dynamics and deuterium exchange mass spectrometry. 15 Jun 2009
- Enhanced transdermal absorption and pharmacokinetic evaluation of pranoprofen-ethylene-vinyl acetate matrix containing penetration enhancer in rats. 25 May 2009
- The action of zymosan on octanoate transport and metabolism in the isolated perfused rat liver. 29 Apr 2009
- Rescue of Abeta(1-42)-induced memory impairment in day-old chick by facilitation of astrocytic oxidative metabolism: implications for Alzheimer's disease. 29 Apr 2009
- Discovery and antibacterial activity of glabramycin A-C from Neosartorya glabra by an antisense strategy. Apr 2009
- Prophylactic supplementation of caprylic acid in feed reduces Salmonella enteritidis colonization in commercial broiler chicks. 30 Mar 2009
- Phenotypic dichotomy following developmental exposure to perfluorooctanoic acid (PFOA) in female CD-1 mice: Low doses induce elevated serum leptin and insulin, and overweight in mid-life. 7 Mar 2009
- Perfluoroalkyl chemicals and human fetal development: an epidemiologic review with clinical and toxicological perspectives. 18 Feb 2009
- Antimicrobial activities of components of the glandular secretions of leaf cutting ants of the genus Atta. 11 Feb 2009
- Gene expression profiling in the liver and lung of perfluorooctane sulfonate-exposed mouse fetuses: comparison to changes induced by exposure to perfluorooctanoic acid. 4 Feb 2009
- Effects of co-exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin and perfluorooctane sulfonate or perfluorooctanoic acid on expression of cytochrome P450 isoforms in chicken (Gallus gallus) embryo hepatocyte cultures. 8 Jan 2009
- The natural feed additive caprylic acid decreases Campylobacter jejuni colonization in market-aged broiler chickens. 30 Dec 2008
- The relationship between birth weight, gestational age and perfluorooctanoic acid (PFOA)-contaminated public drinking water. 11 Nov 2008
- NMR studies on binding sites and aggregation-disassociation of fluorinated surfactant sodium perfluorooctanoate on protein ubiquitin. Nov 2008
- Differential effects of peripubertal exposure to perfluorooctanoic acid on mammary gland development in C57Bl/6 and Balb/c mouse strains. 30 Oct 2008
- Regulation of adipogenesis by medium-chain fatty acids in the absence of hormonal cocktail. 9 Sep 2008
- The application of perfluorooctanoate to investigate trimerization of the human immunodeficiency virus-1 gp41 ectodomain by electrophoresis. 30 Jul 2008
- Therapeutic supplementation of caprylic acid in feed reduces Campylobacter jejuni colonization in broiler chicks.
21 May 2008
See a longer list of these articles.
Technical information about 'Octanoic Acids'
Registry Number: 0
Descriptor UI: D009796
Alternative terms: Octanoic Acids; Acids, Octanoic;
Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;
Tree Number: D02.241.081.222.572; D10.251.122.572;
Online Note: search CAPRYLATES 1968-74
History Note: 91(75); was see under CAPRYLATES 1975-90