Oligodeoxyribonucleotides, Antisense - Pharmacology
Research News and Information

Sunday, November 22, 2009

Homer regulates calcium signalling in growth cone turning.

Aug 2009 BACKGROUND: Homer proteins are post-synaptic density proteins with known functions in receptor trafficking and calcium homeostasis. While they are key mediators of synaptic plasticity, they are also known to function in axon guidance, albeit by ... Read more...

Reversal of RNA dominance by displacement of protein sequestered on triplet repeat RNA.

15 Jul 2009 Genomic expansions of simple tandem repeats can give rise to toxic RNAs that contain expanded repeats. In myotonic dystrophy, the expression of expanded CUG repeats (CUGexp) causes abnormal regulation of alternative splicing and neuromuscular ... Read more...

A new and efficient method for inhibition of RNA viruses by DNA interference.

13 Jul 2009 We report here a new method for inhibition of RNA viruses induced by dsDNA. We demonstrated that both long dsDNA molecules and short interfering DNA with a sequence complementary to that of viral RNA inhibited tobacco mosaic virus expression and ... Read more...

Latest indexed articles for 'Oligodeoxyribonucleotides, Antisense - Pharmacology'

These are the very latest articles for this heading:

• Homer regulates calcium signalling in growth cone turning. Aug 2009
• Reversal of RNA dominance by displacement of protein sequestered on triplet repeat RNA. 15 Jul 2009
• Molecular biology. Neutralizing toxic RNA. 15 Jul 2009
• A new and efficient method for inhibition of RNA viruses by DNA interference. 13 Jul 2009
• Molecular components underlying nongenomic thyroid hormone signaling in embryonic zebrafish neurons. 6 Jun 2009
• The central nucleus of the amygdala and corticotropin-releasing factor: insights into contextual fear memory. Jun 2009
• Reggies/flotillins regulate retinal axon regeneration in the zebrafish optic nerve and differentiation of hippocampal and N2a neurons. 18 May 2009
• Identification of flap structure-specific endonuclease 1 as a factor involved in long-term memory formation of aversive learning. 4 May 2009
• Antiviral effect of ribonuclease conjugated oligodeoxynucleotides targeting the IRES RNA of the hepatitis C virus. 2 May 2009
• Amelioration of hypoperfusion after traumatic brain injury by in vivo endothelin-1 knockout. 29 Apr 2009
• miR-124 regulates adult neurogenesis in the subventricular zone stem cell niche. 13 Mar 2009
• Increased expression of heat shock protein 105 in rat uterus of early pregnancy and its significance in embryo implantation. 11 Mar 2009
• Antisense therapeutics for neurofibromatosis type 1 caused by deep intronic mutations. 27 Feb 2009
• Anti-angiogenesis effect of generation 4 polyamidoamine/vascular endothelial growth factor antisense oligodeoxynucleotide on breast cancer in vitro. 27 Feb 2009
• Olig2+ precursors produce abducens motor neurons and oligodendrocytes in the zebrafish hindbrain. 23 Feb 2009
• Regulatory effects of myoendothelial gap junction on vascular reactivity after hemorrhagic shock in rats. 30 Dec 2008
• GluR6-containing KA receptor mediates the activation of p38 MAP kinase in rat hippocampal CA1 region during brain ischemia injury. 30 Dec 2008
• Effects of stanniocalcin 1 on calcium uptake in zebrafish (Danio rerio) embryo. 8 Dec 2008
• The protective effect of Egr-1 antisense oligodeoxyribonucleotide on myocardial injury induced by ischemia-reperfusion and hypoxia-reoxygenation. 7 Dec 2008
• Hedgehog-induced survival of B-cell chronic lymphocytic leukemia cells in a stromal cell microenvironment: a potential new therapeutic target. 29 Nov 2008

See a longer list of these articles.

Technical information about 'Oligodeoxyribonucleotides, Antisense'

Definition: Short fragments of DNA that are used to alter the function of target RNAs or DNAs to which they hybridize.

Registry Number: 0

Descriptor UI: D020319

Alternative terms: Oligodeoxyribonucleotides, Antisense; Antisense Oligodeoxyribonucleotides; Antisense OligoDNA; OligoDNA, Antisense; Anti-Sense Oligodeoxyribonucleotides; Anti Sense Oligodeoxyribonucleotides; Oligodeoxyribonucleotides, Anti-Sense; Oligodeoxyribonucleotide, Antisense; Antisense Oligodeoxyribonucleotide;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; agonists;

Tree Number: D13.150.200.640; D13.150.480.640; D13.444.308.150.640; D13.444.600.150.200.640; D13.444.600.150.640.640; D13.695.578.424.480.640; D27.720.470.530.600.150.200.640; D27.720.470.530.600.150.640.640;

History Note: 99; was OLIGONUCLEOTIDES, ANTISENSE 1991-98

Technical Notes: DF: ANTISENSE OLIGODNA