Oligodeoxyribonucleotides, Antisense
Research News and Information

Sunday, November 22, 2009

Effect of CD133/prominin-1 antisense oligodeoxynucleotide on in vitro growth characteristics of Huh-7 human hepatocarcinoma cells and U251 human glioma cells.

29 Sep 2009 The stem cell marker CD133/prominin-1, is a pentaspan membrane glycoprotein, which has also been identified as a cancer stem cell (CSC) marker in several solid tumor types, including those of the prostate, liver, colon and brain. The function of ... Read more...

Stimulation of the immune system by therapeutic antisense oligodeoxynucleotides and small interfering RNAs via nucleic acid receptors.

30 Aug 2009 Most of the therapeutic applications for synthetic oligodeoxynucleotides (ODN) and oligoribonucleotides (ORN) relate to mechanisms of manipulating gene expression based on Watson-Crick base pairing to endogenous nucleic acids. However, in recent ... Read more...

Mammalian MagT1 and TUSC3 are required for cellular magnesium uptake and vertebrate embryonic development.

24 Aug 2009 Magnesium (Mg(2+)) is the second most abundant cation in cells, yet relatively few mechanisms have been identified that regulate cellular levels of this ion. The most clearly identified Mg(2+) transporters are in bacteria and yeast. Here, we use a ... Read more...

Latest indexed articles for 'Oligodeoxyribonucleotides, Antisense'

These are the very latest articles for this heading:

• Effect of CD133/prominin-1 antisense oligodeoxynucleotide on in vitro growth characteristics of Huh-7 human hepatocarcinoma cells and U251 human glioma cells. 29 Sep 2009
• Stimulation of the immune system by therapeutic antisense oligodeoxynucleotides and small interfering RNAs via nucleic acid receptors. 30 Aug 2009
• Mammalian MagT1 and TUSC3 are required for cellular magnesium uptake and vertebrate embryonic development. 24 Aug 2009
• Homer regulates calcium signalling in growth cone turning. Aug 2009
• Emx3 is required for the differentiation of dorsal telencephalic neurons. 30 Jul 2009
• Aberrant overexpression of microRNAs activate AKT signaling via down-regulation of tumor suppressors in natural killer-cell lymphoma/leukemia. 27 Jul 2009
• Reversal of RNA dominance by displacement of protein sequestered on triplet repeat RNA. 15 Jul 2009
• Molecular biology. Neutralizing toxic RNA. 15 Jul 2009
• A new and efficient method for inhibition of RNA viruses by DNA interference. 13 Jul 2009
• Opposing actions of neuronal nitric oxide synthase isoforms in formalin-induced pain in mice. 19 Jun 2009
• Zebrafish beta-adrenergic receptor mRNA expression and control of pigmentation. 16 Jun 2009
• Efficient oligonucleotide-mediated degradation of nuclear noncoding RNAs in mammalian cultured cells. 15 Jun 2009
• The P2Y-like receptor GPR17 as a sensor of damage and a new potential target in spinal cord injury. 13 Jun 2009
• Suppression of the immune response potentiates tadpole tail regeneration during the refractory period. 8 Jun 2009
• Molecular components underlying nongenomic thyroid hormone signaling in embryonic zebrafish neurons. 6 Jun 2009
• The central nucleus of the amygdala and corticotropin-releasing factor: insights into contextual fear memory. Jun 2009
• Reggies/flotillins regulate retinal axon regeneration in the zebrafish optic nerve and differentiation of hippocampal and N2a neurons. 18 May 2009
• TRPC1 and TRPC6 channels cooperate with TRPV4 to mediate mechanical hyperalgesia and nociceptor sensitization. 11 May 2009
• Identification of flap structure-specific endonuclease 1 as a factor involved in long-term memory formation of aversive learning. 4 May 2009
• Antiviral effect of ribonuclease conjugated oligodeoxynucleotides targeting the IRES RNA of the hepatitis C virus. 2 May 2009

See a longer list of these articles.

Technical information about 'Oligodeoxyribonucleotides, Antisense'

Definition: Short fragments of DNA that are used to alter the function of target RNAs or DNAs to which they hybridize.

Registry Number: 0

Descriptor UI: D020319

Alternative terms: Oligodeoxyribonucleotides, Antisense; Antisense Oligodeoxyribonucleotides; Antisense OligoDNA; OligoDNA, Antisense; Anti-Sense Oligodeoxyribonucleotides; Anti Sense Oligodeoxyribonucleotides; Oligodeoxyribonucleotides, Anti-Sense; Oligodeoxyribonucleotide, Antisense; Antisense Oligodeoxyribonucleotide;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; agonists;

Tree Number: D13.150.200.640; D13.150.480.640; D13.444.308.150.640; D13.444.600.150.200.640; D13.444.600.150.640.640; D13.695.578.424.480.640; D27.720.470.530.600.150.200.640; D27.720.470.530.600.150.640.640;

History Note: 99; was OLIGONUCLEOTIDES, ANTISENSE 1991-98

Technical Notes: DF: ANTISENSE OLIGODNA