Oligosaccharides - Chemistry
Research News and Information

Monday, November 23, 2009

Identification of the UDP-N-acetylglucosamine 4-epimerase involved in exosporium protein glycosylation in Bacillus anthracis.

9 Sep 2009 Spores of Bacillus anthracis, the causative agent of anthrax, are enclosed by a loosely fitting exosporium composed of a basal layer and an external hair-like nap. The filaments of the nap are formed by trimers of the collagen-like glycoprotein ... Read more...

Conformational flexibility and dynamics of two (1-->6)-linked disaccharides related to an oligosaccharide epitope expressed on malignant tumour cells.

5 Sep 2009 The conformational flexibility and dynamics of two (1-->6)-linked disaccharides that are related to the action of the glycosyl transferase GnT-V have been investigated. NMR NOE and T-ROE spectroscopy experiments, conformation-dependent coupling ... Read more...

Mass spectrometric study of N-glycans from serum of woodchucks with liver cancer.

30 Aug 2009 Woodchucks have been a preferred lab animal model of chronic hepatitis B viral infection. The model recapitulates the disease progression of HBV infection to hepatocellular carcinoma (HCC) and has documented similarities in protein glycosylation ... Read more...

Latest indexed articles for 'Oligosaccharides - Chemistry'

These are the very latest articles for this heading:

• 2009 Claude S. Hudson Award in Carbohydrate Chemistry. Carbohydrates: a frontier in medicinal chemistry. 22 Sep 2009
• Identification of the UDP-N-acetylglucosamine 4-epimerase involved in exosporium protein glycosylation in Bacillus anthracis. 9 Sep 2009
• Conformational flexibility and dynamics of two (1-->6)-linked disaccharides related to an oligosaccharide epitope expressed on malignant tumour cells. 5 Sep 2009
• Mass spectrometric study of N-glycans from serum of woodchucks with liver cancer. 30 Aug 2009
• Evaluation of angiogenic activities of hyaluronan oligosaccharides of defined minimum size. 27 Aug 2009
• Production of beta-maltooligosaccharides of alpha- and delta-tocopherols by Klebsiella pneumoniae and cyclodextrin glucanotransferase as anti-allergic agents. 18 Aug 2009
• A convenient method for synthesis of glyconanoparticles for colorimetric measuring carbohydrate-protein interactions. 17 Aug 2009
• Study of free oligosaccharides derived from the bacterial N-glycosylation pathway. 12 Aug 2009
• When sugars get wet. A comprehensive study of the behavior of water on the surface of oligosaccharides. 4 Aug 2009
• The signature 3-O-sulfo group of the anticoagulant heparin sequence is critical for heparin binding to antithrombin but is not required for allosteric activation. 4 Aug 2009
• Synthesis of 2-C-branched oligo(glyco-amino acid)s (OGAAs) by ring opening of 1,2-cyclopropanecarboxylated sugar donors. Aug 2009
• Complete 1H and 13C NMR assignments of four new oligosaccharides and two new glycosides from Periploca forrestii. 30 Jul 2009
• Structure, mechanistic action, and essential residues of a GH-64 enzyme, laminaripentaose-producing beta-1,3-glucanase. 27 Jul 2009
• Immunological response from an entirely carbohydrate antigen: design of synthetic vaccines based on Tn-PS A1 conjugates. 20 Jul 2009
• Chemistry of a new investigational quadrivalent meningococcal conjugate vaccine that is immunogenic at all ages. 16 Jul 2009
• Isolation and characterization of contaminants in recalled unfractionated heparin and low-molecular-weight heparin. 15 Jul 2009
• Progress in biomimetic carbohydrate recognition. 5 Jul 2009
• Synthesis of oligosaccharide-branched ribofuranan by ring-opening polymerization of a new anhydroribo trisaccharide monomer. 5 Jul 2009
• Efficient synthesis of the deoxysugar part of versipelostatin by direct and stereoselective glycosylation and revision of the structure of the trisaccharide unit. 4 Jul 2009
• O-Glycosylated 24 kDa human growth hormone has a mucin-like biantennary disialylated tetrasaccharide attached at Thr-60. 29 Jun 2009

See a longer list of these articles.

Technical information about 'Oligosaccharides'

Definition: Carbohydrates consisting of between two (DISACCHARIDES) and ten MONOSACCHARIDES connected by either an alpha- or beta-glycosidic link. They are found throughout nature in both the free and bound form.

Registry Number: 0

Descriptor UI: D009844

Alternative terms: Oligosaccharides;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists; ultrastructure;

Tree Number: D09.698.629;

Technical Notes: GEN; prefer specifics