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Oxidants
Research News and Information
Definition of 'Oxidants'Oxidizing agents or electron-accepting molecules in chemical reactions in which electrons are transferred from one molecule to another (OXIDATION-REDUCTION). In vivo, it appears that phagocyte-generated oxidants function as tumor promoters or cocarcinogens rather than as complete carcinogens perhaps because of the high levels of endogenous antioxidant defenses. It is also thought that oxidative damage in joints may trigger the autoimmune response that characterizes the persistence of the rheumatoid disease process. |
Sunday, November 22, 2009
12 Oct 2009 
In Alzheimer's disease (AD), rod-like cofilin aggregates (cofilin-actin rods) and thread-like inclusions containing phosphorylated microtubule-associated protein (pMAP) tau form in the brain (neuropil threads), and the extent of their presence ... Read more...
Suppression of KATP channel activity protects murine pancreatic beta cells against oxidative stress.
29 Sep 2009 The enhanced oxidative stress associated with type 2 diabetes mellitus contributes to disease pathogenesis. We previously identified plasma membrane-associated ATP-sensitive K+ (KATP) channels of pancreatic beta cells as targets for oxidants. Here, ... Read more...
29 Sep 2009 Autoimmune dry eye (Sjögren's syndrome, SS) is a chronic systemic disease characterized by salivary and lacrimal gland inflammation and tissue damage leading to keratoconjunctivitis sicca and xerostomia. In this review attention has been devoted to ... Read more...
Latest indexed articles for 'Oxidants'
These are the very latest articles for this heading:
- Activated actin-depolymerizing factor/cofilin sequesters phosphorylated microtubule-associated protein during the assembly of alzheimer-like neuritic cytoskeletal striations. 12 Oct 2009
- Suppression of KATP channel activity protects murine pancreatic beta cells against oxidative stress. 29 Sep 2009
- Ocular surface injuries in autoimmune dry eye. The severity of microscopical disturbances goes parallel with the severity of symptoms of dryness. 29 Sep 2009
- Combination treatment of hydrogen peroxide and X-rays induces apoptosis in human prostate cancer PC-3 cells. 29 Sep 2009
- Increased susceptibility of aged hearts to ventricular fibrillation during oxidative stress. 16 Sep 2009
- Oxidant-induced apoptosis is mediated by oxidation of the actin-regulatory protein cofilin. 4 Sep 2009
- Differentiation-associated loss of ryanodine receptors: a strategy adopted by monocytes/macrophages to prevent the DNA single-strand breakage induced by peroxynitrite. 2 Sep 2009
- In vitro translocation of quantum dots and influence of oxidative stress. 2 Sep 2009
- Effect of vital tooth bleaching on solubility and roughness of dental cements. 30 Aug 2009
- The OsDHODH1 gene is involved in salt and drought tolerance in rice. 30 Aug 2009
- Oxidative injury triggers autophagy in astrocytes: the role of endogenous zinc. 30 Aug 2009
- What is the pertinent finding and an explanation for the cause?
30 Aug 2009 - Oxidative modifications of S100 proteins: functional regulation by redox. 30 Aug 2009
- Glutathionylation of p65NF-kappaB correlates with proliferating/apoptotic hepatoma cells exposed to pro- and anti-oxidants. 30 Aug 2009
- Pathogenic stimulation of intestinal stem cell response in Drosophila. 30 Aug 2009
- Phosphorylation of caveolin-1 regulates oxidant-induced pulmonary vascular permeability via paracellular and transcellular pathways. 25 Aug 2009
- Transglutaminase-1 protects renal epithelial cells from hydrogen peroxide-induced apoptosis through activation of STAT3 and AKT signaling pathways. 24 Aug 2009
- Protein phosphatase 5 protects neurons against amyloid-beta toxicity. 15 Aug 2009
- Generation of oxidant response to copper and iron nanoparticles and salts: Stimulation by ascorbate. 12 Aug 2009
- Pd(II)-catalyzed amination of C-H bonds using single-electron or two-electron oxidants. 10 Aug 2009
See a longer list of these articles.
Technical information about 'Oxidants'
Definition: Oxidizing agents or electron-accepting molecules in chemical reactions in which electrons are transferred from one molecule to another (OXIDATION-REDUCTION). In vivo, it appears that phagocyte-generated oxidants function as tumor promoters or cocarcinogens rather than as complete carcinogens perhaps because of the high levels of endogenous antioxidant defenses. It is also thought that oxidative damage in joints may trigger the autoimmune response that characterizes the persistence of the rheumatoid disease process.
Registry Number: 0
Descriptor UI: D016877
Alternative terms: Oxidants; Oxidizing Agents; Agents, Oxidizing;
Related Mesh Headings: Antioxidants;
Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists; biosynthesis; physiology;
Tree Number: D27.720.642; D27.888.569.540;
History Note: 92
Technical Notes: /biosyn /physiol permitted