Oxidative Stress - Drug effects
Research News and Information

Saturday, November 21, 2009

p38SJ, a novel DINGG protein protects neuronal cells from alcohol induced injury and death.

29 Nov 2009 Ethanol induces neuronal cell injury and death by dysregulating several signaling events that are controlled, in part, by activation of MAPK/ERK1/2 and/or inactivation of its corresponding phosphatase, PP1. Recently, we have purified a novel protein ... Read more...

Protective effect of sulfhydryl-containing antioxidants against ischemia/reperfusion injury of prepubertal rat intestine.

29 Nov 2009 BACKGROUND AND AIM: Reactive oxygen species generated during reperfusion of the tissue are known to play an important role in the basic pathophysiology of ischemia/reperfusion (I/R) injury. The aim of this study was to investigate and compare the ... Read more...

Membrane-dependent bystander effect contributes to amplification of the response to alpha-particle irradiation in targeted and nontargeted cells.

13 Nov 2009 PURPOSE: Free radicals are believed to play an active role in the bystander response. This study investigated their origin as well as their temporal and spatial impacts in the bystander effect. METHODS AND MATERIALS: We employed a precise ... Read more...

Latest indexed articles for 'Oxidative Stress - Drug effects'

These are the very latest articles for this heading:

• p38SJ, a novel DINGG protein protects neuronal cells from alcohol induced injury and death. 29 Nov 2009
• Protective effect of sulfhydryl-containing antioxidants against ischemia/reperfusion injury of prepubertal rat intestine. 29 Nov 2009
• Membrane-dependent bystander effect contributes to amplification of the response to alpha-particle irradiation in targeted and nontargeted cells. 13 Nov 2009
• Estrogen attenuates ischemic oxidative damage via an estrogen receptor alpha-mediated inhibition of NADPH oxidase activation. 2 Nov 2009
• Hemolytic anemia after zopiclone overdose. 30 Oct 2009
• W7FW14F apomyoglobin amyloid aggregates-mediated apoptosis is due to oxidative stress and AKT inactivation caused by Ras and Rac. 30 Oct 2009
• Upregulation of peroxisome proliferator-activated receptor-gamma and NADPH oxidases are involved in restenosis after balloon injury. 30 Oct 2009
• Importance of the bioenergetic reserve capacity in response to cardiomyocyte stress induced by 4-hydroxynonenal. 21 Oct 2009
• Nebivolol: the somewhat-different beta-adrenergic receptor blocker. 11 Oct 2009
• Lycopene modulates nitric oxide pathways against 3-nitropropionic acid-induced neurotoxicity. 10 Oct 2009
• Suppression of KATP channel activity protects murine pancreatic beta cells against oxidative stress. 29 Sep 2009
• Differential effects of non-steroidal anti-inflammatory drugs on mitochondrial dysfunction during oxidative stress. 29 Sep 2009
• Hepatocyte growth factor protects auditory hair cells from aminoglycosides. 29 Sep 2009
• Zinc supplementation reverses alcohol-induced steatosis in mice through reactivating hepatocyte nuclear factor-4alpha and peroxisome proliferator-activated receptor-alpha. 29 Sep 2009
• Evidence for the association of peroxidases with the antioxidant effect of p-coumaric acid in endothelial cells exposed to high glucose plus arachidonic acid. 28 Sep 2009
• Effect of cardiorespiratory fitness on vascular regulation and oxidative stress in postmenopausal women. 26 Sep 2009
• Effect of alpha tocopherol acetate in Walker 256/B cells-induced oxidative damage in a rat model of breast cancer skeletal metastases. 21 Sep 2009
• Hepatocyte growth factor prevents advanced glycation end products-induced injury and oxidative stress through a PI3K/Akt-dependent pathway in human endothelial cells. 20 Sep 2009
• Pressure-induced vascular oxidative stress is mediated through activation of integrin-linked kinase 1/betaPIX/Rac-1 pathway. 19 Sep 2009
• A new PIXel in the puzzle: how increased vascular pressure induces oxidative stress. 19 Sep 2009

See a longer list of these articles.

Technical information about 'Oxidative Stress'

Definition: A disturbance in the prooxidant-antioxidant balance in favor of the former, leading to potential damage. Indicators of oxidative stress include damaged DNA bases, protein oxidation products, and lipid peroxidation products (Sies, Oxidative Stress, 1991, pxv-xvi).

Descriptor UI: D018384

Alternative terms: Oxidative Stress; Oxidative Stresses; Stresses, Oxidative; Stress, Oxidative;

Allowable Qualifiers: drug effects; genetics; immunology; physiology; radiation effects;

Tree Number: G03.495.710; G07.700.830.750;

History Note: 95