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Oxidative Stress
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Definition of 'Oxidative Stress'

A disturbance in the prooxidant-antioxidant balance in favor of the former, leading to potential damage. Indicators of oxidative stress include damaged DNA bases, protein oxidation products, and lipid peroxidation products (Sies, Oxidative Stress, 1991, pxv-xvi).

Common names: Oxidative Stress; Oxidative Stresses; Stresses, Oxidative; Stress, Oxidative

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Saturday, November 21, 2009

Elevated serum macrophage migration inhibitory factor (MIF) concentrations in chronic kidney disease (CKD) are associated with markers of oxidative stress and endothelial activation.

6 Dec 2009 Chronic kidney disease (CKD) carries an increased risk of cardiovascular disease (CVD). Macrophage migration inhibiting factor (MIF) is a proinflammatory cytokine implicated in the pathogenesis of sepsis, autoimmune disease, atherogenesis, and ... Read more...


p38SJ, a novel DINGG protein protects neuronal cells from alcohol induced injury and death.

29 Nov 2009 Ethanol induces neuronal cell injury and death by dysregulating several signaling events that are controlled, in part, by activation of MAPK/ERK1/2 and/or inactivation of its corresponding phosphatase, PP1. Recently, we have purified a novel protein ... Read more...


Protective effect of sulfhydryl-containing antioxidants against ischemia/reperfusion injury of prepubertal rat intestine.

29 Nov 2009 BACKGROUND AND AIM: Reactive oxygen species generated during reperfusion of the tissue are known to play an important role in the basic pathophysiology of ischemia/reperfusion (I/R) injury. The aim of this study was to investigate and compare the ... Read more...

 

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Technical information about 'Oxidative Stress'

Definition: A disturbance in the prooxidant-antioxidant balance in favor of the former, leading to potential damage. Indicators of oxidative stress include damaged DNA bases, protein oxidation products, and lipid peroxidation products (Sies, Oxidative Stress, 1991, pxv-xvi).

Descriptor UI: D018384

Alternative terms: Oxidative Stress; Oxidative Stresses; Stresses, Oxidative; Stress, Oxidative;

Allowable Qualifiers: drug effects; genetics; immunology; physiology; radiation effects;

Tree Number: G03.495.710; G07.700.830.750;

History Note: 95

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