Oxycodone
Research News and Information

Sunday, March 21, 2010

A comparison of intravenous oxycodone and intravenous morphine in patient-controlled postoperative analgesia after laparoscopic hysterectomy.

29 Sep 2009 INTRODUCTION: In this study, we investigated the dose requirements, pain relief, and side effects of oxycodone versus morphine after surgery with visceral pain. METHODS: Ninety-one women received IV oxycodone or morphine before the end of ... Read more...

Analgesic efficacy of peripheral kappa-opioid receptor agonist CR665 compared to oxycodone in a multi-modal, multi-tissue experimental human pain model: selective effect on visceral pain.

30 Aug 2009 BACKGROUND: Peripherally selective opioids may be beneficial in visceral pain management due to absence of centrally mediated side effects. The objectives of this study were: (1) to assess the effects of a peripherally selective tetrapeptide ... Read more...

Evidence-based review of clinical studies on pharmacology (non-anesthetic studies).

30 Jul 2009 We have divided the analysis of pharmacology studies into studies on local anesthetics and studies on all other pharmacologic agents. This division reflects the large number of studies focusing on methods for obtaining effective anesthesia in ... Read more...

Latest indexed articles for 'Oxycodone'

These are the very latest articles for this heading:

• A comparison of intravenous oxycodone and intravenous morphine in patient-controlled postoperative analgesia after laparoscopic hysterectomy. 29 Sep 2009
• Analgesic efficacy of peripheral kappa-opioid receptor agonist CR665 compared to oxycodone in a multi-modal, multi-tissue experimental human pain model: selective effect on visceral pain. 30 Aug 2009
• Evidence-based review of clinical studies on pharmacology (non-anesthetic studies). 30 Jul 2009
• Oxycodone: new 'old' drug. 30 Jul 2009
• The effective analgesic dose of dexamethasone after laparoscopic hysterectomy. 30 Jul 2009
• Single dose oral oxycodone and oxycodone plus paracetamol (acetaminophen) for acute postoperative pain in adults. 6 Jul 2009
• 2009 Clinical Guidelines from the American Pain Society and the American Academy of Pain Medicine on the use of chronic opioid therapy in chronic noncancer pain: what are the key messages for clinical practice? 29 Jun 2009
• Relationship between rate of infusion and reinforcing strength of oxycodone in humans. 29 Jun 2009
• HIV risk behavior in opioid dependent adults seeking detoxification treatment: an exploratory comparison of heroin and oxycodone users. 29 Jun 2009
• Does 1 or 2 g paracetamol added to ketoprofen enhance analgesia in adult tonsillectomy patients? 28 Jun 2009
• Rifampin greatly reduces the plasma concentrations of intravenous and oral oxycodone. 30 May 2009
• Diversion of opioid pain medications at end-of-life. 24 May 2009
• Opioid-induced bowel dysfunction in cancer-related pain: causes, consequences, and a novel approach for its management. 29 Apr 2009
• Tolerability of tapentadol immediate release in patients with lower back pain or osteoarthritis of the hip or knee over 90 days: a randomized, double-blind study. 29 Apr 2009
• Restless legs syndrome. 29 Apr 2009
• Importance of using highly pure internal standards for successful liquid chromatography/tandem mass spectrometric bioanalytical assays. 29 Apr 2009
• Continuous interscalene brachial plexus block via an ultrasound-guided posterior approach: a randomized, triple-masked, placebo-controlled study. 29 Apr 2009
• [Tolerated opioid therapy with oxycodone/naloxone. Better quality of life for osteoporosis patients] 28 Apr 2009
• [Modern pain therapy with dual advantage. Strong analgesia and superior tolerance] 28 Apr 2009
• Cross-reactivity of naloxone with oxycodone immunoassays: implications for individuals taking Suboxone. 28 Apr 2009

See a longer list of these articles.

Technical information about 'Oxycodone'

Definition: Semisynthetic derivative of CODEINE that acts as a narcotic analgesic more potent and addicting than codeine.

Chemical name: Morphinan-6-one, 4,5-epoxy-14-hydroxy-3-methoxy-17-methyl-, (5alpha)-

Registry Number: 76-42-6

Descriptor UI: D010098

Alternative terms: Oxycodone; Dihydrohydroxycodeinone; Oxycodeinon; Dinarkon; Eucodal; Hydroxycodeinon; Oxiconum; Oxycone; Oxycontin; Pancodine; Theocodin; Dihydrone; Oxycodone Hydrochloride;

Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Pharmacological Action: Narcotics; Analgesics, Opioid;

Tree Number: D03.132.577.249.547.547.149.575; D03.549.686.575.547.204.650; D03.605.497.575.547.204.650; D04.615.723.795.547.547.149.575;

History Note: 91(76); was see under CODEINE 1976-90