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Pain - Physiopathology
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Definition of 'Pain'

An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.

Common names: Pain; Pain, Burning; Burning Pain; Burning Pains; Pains, Burning; Suffering, Physical; Physical Suffering; Physical Sufferings; Sufferings, Physical; Pain, Migratory; Migratory Pain; Migratory Pains; Pains, Migratory; Pain, Radiating; Pains, Radiating; Radiating Pain; Radiating Pains

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Saturday, November 21, 2009

Enduring reversal of neuropathic pain by a single intrathecal injection of adenosine 2A receptor agonists: a novel therapy for neuropathic pain.

2 Nov 2009 Previous studies of peripheral immune cells have documented that activation of adenosine 2A receptors (A(2A)Rs) decrease proinflammatory cytokine release and increase release of the potent anti-inflammatory cytokine, interleukin-10 (IL-10). Given ... Read more...


The effect of a thoracic spinal block on fos expression in the lumbar spinal cord of the rat induced by a noxious electrical stimulus at the hindpaw.

30 Oct 2009 BACKGROUND: Fos expression in the lumbar spinal cord, resulting from a noxious electrical stimulus at the hindpaw, is hypothesized to originate from three sources: direct sensory input of the noxious stimulus, local interactions in the spinal cord, ... Read more...


Validity of electrical stimulus magnitude matching in chronic pain.

30 Oct 2009 OBJECTIVE: To examine the validity of the PainMatcher in chronic pain. DESIGN: Comparison of parallel pain estimates from visual analogue scales with electrical stimulus magnitude matching. PATIENTS: Thirty-one patients with chronic musculoskeletal ... Read more...

 

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Technical information about 'Pain'

Definition: An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.

Descriptor UI: D010146

Alternative terms: Pain; Pain, Burning; Burning Pain; Burning Pains; Pains, Burning; Suffering, Physical; Physical Suffering; Physical Sufferings; Sufferings, Physical; Pain, Migratory; Migratory Pain; Migratory Pains; Pains, Migratory; Pain, Radiating; Pains, Radiating; Radiating Pain; Radiating Pains; Pain, Splitting; Pains, Splitting; Splitting Pain; Splitting Pains; Ache; Aches; Pain, Crushing; Crushing Pain; Crushing Pains; Pains, Crushing;

Related Mesh Headings: Analgesia; Pain Insensitivity, Congenital; Analgesics; Hyperalgesia; Palliative Care;

Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; congenital; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; urine; veterinary; ultrasonography; virology;

Tree Number: C10.597.617; C23.888.592.612; C23.888.646; F02.830.816.444; G11.561.600.810.444;

Technical Notes: general; prefer specific precoordinated locational pain terms, like ABDOMINAL PAIN; CHEST PAIN, etc.; / diag: consider also PAIN MEASUREMENT but PAIN / diag is probably PAIN / etiol; / ther: consider also PALLIATIVE CARE ( = pain relief without cure); / physiopathol: PAIN THRESHOLD is also available; chronic pain = PAIN (IM) + CHRONIC DISEASE (NIM): do not equate with PAIN, INTRACTABLE; congenital absence of pain = PAIN INSENSITIVITY, CONGENITAL

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