Pain Measurement - Drug effects
Research News and Information

Monday, November 23, 2009

Enduring reversal of neuropathic pain by a single intrathecal injection of adenosine 2A receptor agonists: a novel therapy for neuropathic pain.

2 Nov 2009 Previous studies of peripheral immune cells have documented that activation of adenosine 2A receptors (A(2A)Rs) decrease proinflammatory cytokine release and increase release of the potent anti-inflammatory cytokine, interleukin-10 (IL-10). Given ... Read more...

Proteomic analysis uncovers novel actions of the neurosecretory protein VGF in nociceptive processing.

19 Oct 2009 Peripheral tissue injury is associated with changes in protein expression in sensory neurons that may contribute to abnormal nociceptive processing. We used cultured dorsal root ganglion (DRG) neurons as a model of axotomized neurons to investigate ... Read more...

Analgesic efficacy of peripheral kappa-opioid receptor agonist CR665 compared to oxycodone in a multi-modal, multi-tissue experimental human pain model: selective effect on visceral pain.

30 Aug 2009 BACKGROUND: Peripherally selective opioids may be beneficial in visceral pain management due to absence of centrally mediated side effects. The objectives of this study were: (1) to assess the effects of a peripherally selective tetrapeptide ... Read more...

Latest indexed articles for 'Pain Measurement - Drug effects'

These are the very latest articles for this heading:

• Enduring reversal of neuropathic pain by a single intrathecal injection of adenosine 2A receptor agonists: a novel therapy for neuropathic pain. 2 Nov 2009
• Proteomic analysis uncovers novel actions of the neurosecretory protein VGF in nociceptive processing. 19 Oct 2009
• Analgesic efficacy of peripheral kappa-opioid receptor agonist CR665 compared to oxycodone in a multi-modal, multi-tissue experimental human pain model: selective effect on visceral pain. 30 Aug 2009
• Intradermal administration of magnesium sulphate and magnesium chloride produces hypesthesia to mechanical but hyperalgesia to heat stimuli in humans. 26 Aug 2009
• Activation of the opioidergic descending pain control system underlies placebo analgesia. 25 Aug 2009
• [Chronic pain therapy] 10 Aug 2009
• Injection in the cervical facet joint for shoulder pain with myofascial trigger points in the upper trapezius muscle. 30 Jul 2009
• The effective duration of analgesia after intrathecal morphine in patients without additional opioid analgesia: a randomized double-blind multicentre study on orthopaedic patients. 30 Jul 2009
• Structure-analgesic activity relationship studies on the C(18)- and C(19)-diterpenoid alkaloids. 30 Jul 2009
• Lumbar sympathetic blockade in children with complex regional pain syndromes: a double blind placebo-controlled crossover trial. 30 Jul 2009
• Depletion of calcium stores in injured sensory neurons: anatomic and functional correlates. 30 Jul 2009
• The antinociceptive effects of intravenous dexmedetomidine in colorectal distension-induced visceral pain in rats: the role of opioid receptors. 30 Jul 2009
• Morphine-based cardiac anesthesia provides superior early recovery compared with fentanyl in elective cardiac surgery patients. 30 Jul 2009
• Long-term pain vulnerability after surgery in rats: prevention by nefopam, an analgesic with antihyperalgesic properties. 30 Jul 2009
• The effect of kappa-opioid receptor agonists on tetrodotoxin-resistant sodium channels in primary sensory neurons. 30 Jul 2009
• Long-lasting infiltration anaesthesia by lidocaine-loaded biodegradable nanoparticles in hydrogel in rats. 27 Jul 2009
• The Rac GTPase-activating bacterial protein toxin CNF1 induces analgesia up-regulating mu-opioid receptors. 13 Jul 2009
• Suppressive effects of lamotrigine on the development and expression of tolerance to morphine-induced antinociception in the male mouse. 13 Jul 2009
• Serial therapeutic sacroiliac joint injections: a practice audit. 4 Jul 2009
• 6beta-naltrexol preferentially antagonizes opioid effects on gastrointestinal transit compared to antinociception in mice. 3 Jul 2009

See a longer list of these articles.

Technical information about 'Pain Measurement'

Definition: Scales, questionnaires, tests, and other methods used to assess pain severity and duration in patients or experimental animals to aid in diagnosis, therapy, and physiological studies.

Descriptor UI: D010147

Alternative terms: Pain Measurement; Measurement, Pain; Measurements, Pain; Pain Measurements; Pain Assessment; Nociception Tests; Nociception Test; Test, Nociception; Tests, Nociception; Analgesia Tests; Analgesia Test; Test, Analgesia; Tests, Analgesia; Assessment, Pain; Assessments, Pain; Pain Assessments; Visual Analog Scale; Scale, Visual Analog; Scales, Visual Analog; Visual Analog Scales; Visual Analogue Pain Scale; Visual Analogue Scale; Analogue Scale, Visual; Analogue Scales, Visual; Scale, Visual Analogue; Scales, Visual Analogue; Visual Analogue Scales; Visual Analog Pain Scale; McGill Pain Questionnaire; Pain Questionnaire, McGill; Questionnaire, McGill Pain; McGill Pain Scale; Pain Scale, McGill; Scale, McGill Pain; Tourniquet Pain Test; Pain Test, Tourniquet; Pain Tests, Tourniquet; Test, Tourniquet Pain; Tests, Tourniquet Pain; Tourniquet Pain Tests; Analogue Pain Scale; Analogue Pain Scales; Pain Scale, Analogue; Pain Scales, Analogue; Scale, Analogue Pain; Scales, Analogue Pain; Analog Pain Scale; Analog Pain Scales; Pain Scale, Analog; Pain Scales, Analog; Scale, Analog Pain; Scales, Analog Pain; Formalin Test; Formalin Tests; Test, Formalin; Tests, Formalin;

Related Mesh Headings: Sensory Thresholds; Pain Threshold;

Allowable Qualifiers: adverse effects; classification; drug effects; economics; history; instrumentation; methods; mortality; nursing; psychology; radiation effects; standards; trends; utilization; veterinary; statistics & numerical data; contraindications; ethics;

Tree Number: E01.370.376.550.600;

History Note: 87