Pancreatic Neoplasms
Research News and Information

Sunday, November 22, 2009

Fisetin, a natural flavonoid, targets chemoresistant human pancreatic cancer AsPC-1 cells through DR3-mediated inhibition of NF-kappaB.

13 Nov 2009 Death receptors of the tumor necrosis factor (TNF) receptor super family have been implicated in constitutive activation of nuclear factor-kappa B (NF-kappaB) in pancreatic cancer (PaC) cells. In this study, we demonstrate that fisetin, a natural ... Read more...

CD44-positive cells are responsible for gemcitabine resistance in pancreatic cancer cells.

13 Nov 2009 Accumulating evidence suggests that tumors are composed of a heterogeneous cell population with a small subset of cancer stem cells (CSCs) that sustain tumor formation and growth. Recently, there have been efforts to explain drug resistance of ... Read more...

Radiosensitization effect of STI-571 on pancreatic cancer cells in vitro.

30 Oct 2009 PURPOSE: To examine STI-571-induced radiosensitivity in human pancreatic cancer cells in vitro. METHODS AND MATERIALS: Three human pancreatic cancer cell lines (Bxpc-3, Capan-1, and MiaPaCa-2) exhibiting different expression levels of c-Kit and ... Read more...

Latest indexed articles for 'Pancreatic Neoplasms'

These are the very latest articles for this heading:

• Fisetin, a natural flavonoid, targets chemoresistant human pancreatic cancer AsPC-1 cells through DR3-mediated inhibition of NF-kappaB. 13 Nov 2009
• CD44-positive cells are responsible for gemcitabine resistance in pancreatic cancer cells. 13 Nov 2009
• Radiosensitization effect of STI-571 on pancreatic cancer cells in vitro. 30 Oct 2009
• Risk of pancreatic cancer in families with Lynch syndrome. 26 Oct 2009
• Obesity and survival among patients with pancreatic cancer. 26 Oct 2009
• Novel triazole ribonucleoside down-regulates heat shock protein 27 and induces potent anticancer activity on drug-resistant pancreatic cancer. 6 Oct 2009
• Molecular changes in pancreatic cancer. 29 Sep 2009
• Novel agents for the treatment of adenocarcinoma of the pancreas. 29 Sep 2009
• HuR modulates gemcitabine efficacy: new perspectives in pancreatic cancer treatment. 29 Sep 2009
• Screening for familial pancreatic cancer: is doing something better than doing nothing? 29 Sep 2009
• Norepinephrine-induced invasion by pancreatic cancer cells is inhibited by propranolol. 29 Sep 2009
• A step in the right direction, but one size might not fit all. 29 Sep 2009
• Completion pancreatectomy and duodenectomy for recurrent MEN-1 pancreaticoduodenal endocrine neoplasms. 29 Sep 2009
• A prospective single institution comparison of peri-operative outcomes for laparoscopic and open distal pancreatectomy. 29 Sep 2009
• MRI features of pancreatic colloid carcinoma. 29 Sep 2009
• Ex vivo expanded telomerase-specific T cells are effective in an orthotopic mouse model for pancreatic adenocarcinoma. 29 Sep 2009
• Is there an indication for initial conservative management of pancreatic cystic lesions? 29 Sep 2009
• E-cadherin in solid pseudopapillary tumors of the pancreas--reply. 29 Sep 2009
• Review of adjuvant radiochemotherapy for resected pancreatic cancer and results from Mayo Clinic for the 5th JUCTS symposium. 29 Sep 2009
• HOX D13 expression across 79 tumor tissue types. 29 Sep 2009

See a longer list of these articles.

Technical information about 'Pancreatic Neoplasms'

Definition: Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).

Descriptor UI: D010190

Alternative terms: Pancreatic Neoplasms; Neoplasm, Pancreatic; Pancreatic Neoplasm; Neoplasms, Pancreatic; Pancreas Neoplasms; Neoplasm, Pancreas; Neoplasms, Pancreas; Pancreas Neoplasm; Cancer of Pancreas; Pancreas Cancers; Pancreas Cancer; Cancer, Pancreas; Cancers, Pancreas; Pancreatic Cancer; Cancer, Pancreatic; Cancers, Pancreatic; Pancreatic Cancers; Cancer of the Pancreas;

Allowable Qualifiers: blood; blood supply; cerebrospinal fluid; chemically induced; classification; complications; congenital; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; secondary; secretion; surgery; therapy; ultrastructure; urine; veterinary; ultrasonography; chemistry; virology;

Tree Number: C04.588.274.761; C04.588.322.421; C06.301.761; C06.689.667; C19.344.421;

Technical Notes: coord IM with histol type of neopl (IM); available are ALPHA-CELL TUMOR see GLUCAGONOMA; BETA-CELL TUMOR see INSULINOMA; and pancreatic delta-cell tumor see SOMATOSTATINOMA