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Parathyroid Hormone - Administration & dosage
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Definition of 'Parathyroid Hormone'

A polypeptide hormone (84 amino acid residues) secreted by the PARATHYROID GLANDS which performs the essential role of maintaining intracellular CALCIUM levels in the body. Parathyroid hormone increases intracellular calcium by promoting the release of CALCIUM from BONE, increases the intestinal absorption of calcium, increases the renal tubular reabsorption of calcium, and increases the renal excretion of phosphates.

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Sunday, November 22, 2009

Rapamycin impairs trabecular bone acquisition from high-dose but not low-dose intermittent parathyroid hormone treatment.

29 Nov 2009 The osteo-anabolic effects of intermittent parathyroid hormone (PTH) treatment require insulin-like growth factor (IGF) signaling through the IGF-I receptor. A major downstream target of the IGF-I receptor (via Akt) is the mammalian target of ... Read more...


Short-term effects of parathyroid hormone on rat lumbar vertebrae.

30 Aug 2009 STUDY DESIGN: This study is an experimental study in the rat osteopenia model. OBJECTIVE: The aim of this study was to evaluate the short-term effects of daily application of parathyroid hormone (PTH) on bone quality and quantity using a new ... Read more...


Nmp4/CIZ suppresses parathyroid hormone-induced increases in trabecular bone.

30 May 2009 The nucleocytoplasmic shuttling transcription factor Nmp4/CIZ (nuclear matrix protein 4/cas interacting zinc finger protein) is a ubiquitously expressed protein that regulates both cytoplasmic and nuclear activities. In the nucleus, Nmp4/CIZ ... Read more...

 

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Technical information about 'Parathyroid Hormone'

Definition: A polypeptide hormone (84 amino acid residues) secreted by the PARATHYROID GLANDS which performs the essential role of maintaining intracellular CALCIUM levels in the body. Parathyroid hormone increases intracellular calcium by promoting the release of CALCIUM from BONE, increases the intestinal absorption of calcium, increases the renal tubular reabsorption of calcium, and increases the renal excretion of phosphates.

Registry Number: 0

Descriptor UI: D010281

Alternative terms: Parathyroid Hormone; Hormone, Parathyroid; PTH (1-84); Parathyroid Hormone (1-84); Parathormone; Parathyrin; Parathyroid Hormone Peptide (1-34); PTH(1-34); Parathyroid Hormone (1-34);

Related Mesh Headings: Hypoparathyroidism; Parathyroid Hormone-Related Protein;

Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D06.472.699.590; D12.644.548.587;

History Note: 2004(1963-1981); for PARATHYROID HORMONE PEPTIDE (1-34) use TERIPARATIDE 1997-2007

Technical Notes: /defic: consider also HYPOPARATHYROIDISM

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