Parkinson Disease - Etiology
Research News and Information

Sunday, November 22, 2009

Advanced time-series analysis of MEG data as a method to explore olfactory function in healthy controls and Parkinson's disease patients.

30 Aug 2009 OBJECTIVES: To determine whether time-series analysis of magnetoencephalography (MEG) data is a suitable method to study brain activity related to olfactory information processing, and to detect differences in odor-induced brain activity between ... Read more...

Parkinson-dementia complex and development of a new stable isotope dilution assay for BMAA detection in tissue.

26 Aug 2009 Beta-methylamino-L-alanine (BMAA) has been proposed as a global contributor to neurodegenerative diseases, including Parkinson-dementia complex (PDC) of Guam and Alzheimer's disease (AD). The literature on the effects of BMAA is conflicting with ... Read more...

Etiology and pathogenesis of Parkinson disease.

30 Jul 2009 The etiology of Parkinson disease (PD) is multifactorial and is likely to involve different causes in different patients. Several different genes have been identified as causes of familial PD, including alpha-synuclein gene mutations and ... Read more...

Latest indexed articles for 'Parkinson Disease - Etiology'

These are the very latest articles for this heading:

• Mice with reduced vesicular monoamine storage content display nonmotor features of Parkinson's disease. 12 Oct 2009
• Advanced time-series analysis of MEG data as a method to explore olfactory function in healthy controls and Parkinson's disease patients. 30 Aug 2009
• Parkinson-dementia complex and development of a new stable isotope dilution assay for BMAA detection in tissue. 26 Aug 2009
• Etiology and pathogenesis of Parkinson disease. 30 Jul 2009
• Bell's palsy preceding Parkinson's disease: a case-control study. 28 Jul 2009
• Vanadium induces dopaminergic neurotoxicity via protein kinase Cdelta dependent oxidative signaling mechanisms: relevance to etiopathogenesis of Parkinson's disease. 27 Jul 2009
• Is Parkinson's disease a prion disorder? 26 Jul 2009
• Molecular pathogenesis of Parkinson disease: insights from genetic studies. 25 Jul 2009
• Repression of alpha-synuclein expression and toxicity by microRNA-7. 21 Jul 2009
• Reproductive factors, exogenous estrogen use, and risk of Parkinson's disease. 13 Jul 2009
• Risk is in the air: an intranasal MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) rat model of Parkinson's disease. 29 Jun 2009
• Revelations and revolutions in the understanding of Parkinson's disease. 29 Jun 2009
• Regulation of mitochondrial respiratory chain biogenesis by estrogens/estrogen receptors and physiological, pathological and pharmacological implications. 21 Jun 2009
• Parkinson's disease. 11 Jun 2009
• Two new test methods to quantify motor deficits in a marmoset model for Parkinson's disease. 6 Jun 2009
• [Motor control by the basal ganglia] 30 May 2009
• Intrinsic disorder in proteins associated with neurodegenerative diseases. 30 May 2009
• Transcranial brain sonography findings in Parkinson's disease: implications for pathogenesis, early diagnosis and therapy. 30 May 2009
• [Molecular genetics and pathogenesis of Parkinson disease] 30 May 2009
• Cycad seeds and chronic neurologic disease (Cycas species). 30 May 2009

See a longer list of these articles.

Technical information about 'Parkinson Disease'

Definition: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)

Descriptor UI: D010300

Alternative terms: Parkinson Disease; Idiopathic Parkinson's Disease; Lewy Body Parkinson Disease; Lewy Body Parkinson's Disease; Primary Parkinsonism; Parkinsonism, Primary; Parkinson Disease, Idiopathic; Parkinson's Disease; Parkinson's Disease, Idiopathic; Parkinson's Disease, Lewy Body; Idiopathic Parkinson Disease; Paralysis Agitans;

Related Mesh Headings: Lewy Bodies;

Allowable Qualifiers: blood; cerebrospinal fluid; classification; complications; congenital; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; urine; veterinary; ultrasonography; virology;

Tree Number: C10.228.140.079.862.500; C10.228.662.600.400; C10.574.812;

History Note: 1979(1963)

Technical Notes: drug ther: consider also ANTIPARKINSON AGENTS; /chem ind = PARKINSON DISEASE, SECONDARY/chem ind