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Parkinson Disease - Psychology
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Definition of 'Parkinson Disease'

A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)

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Saturday, November 21, 2009

Incidence of and risk factors for cognitive impairment in an early Parkinson disease clinical trial cohort.

Nov 2009 OBJECTIVE: To investigate the incidence of and risk factors for cognitive impairment in a large, well-defined clinical trial cohort of patients with early Parkinson disease (PD). METHODS: The Mini-Mental State Examination (MMSE) was administered ... Read more...


Driving under low-contrast visibility conditions in Parkinson disease.

4 Oct 2009 OBJECTIVE: To assess driving performance in Parkinson disease (PD) under low-contrast visibility conditions. METHODS: Licensed, active drivers with mild to moderate PD (n = 67, aged 66.2 +/- 9.0 years, median Hoehn-Yahr stage = 2) and controls (n = ... Read more...


Neuroanatomical correlates of impaired decision-making and facial emotion recognition in early Parkinson's disease.

2 Sep 2009 Decision-making and recognition of emotions are often impaired in patients with Parkinson's disease (PD). The orbitofrontal cortex (OFC) and the amygdala are critical structures subserving these functions. This study was designed to test whether ... Read more...

 

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Technical information about 'Parkinson Disease'

Definition: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)

Descriptor UI: D010300

Alternative terms: Parkinson Disease; Idiopathic Parkinson's Disease; Lewy Body Parkinson Disease; Lewy Body Parkinson's Disease; Primary Parkinsonism; Parkinsonism, Primary; Parkinson Disease, Idiopathic; Parkinson's Disease; Parkinson's Disease, Idiopathic; Parkinson's Disease, Lewy Body; Idiopathic Parkinson Disease; Paralysis Agitans;

Related Mesh Headings: Lewy Bodies;

Allowable Qualifiers: blood; cerebrospinal fluid; classification; complications; congenital; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; urine; veterinary; ultrasonography; virology;

Tree Number: C10.228.140.079.862.500; C10.228.662.600.400; C10.574.812;

History Note: 1979(1963)

Technical Notes: drug ther: consider also ANTIPARKINSON AGENTS; /chem ind = PARKINSON DISEASE, SECONDARY/chem ind

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