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Parkinson Disease - Surgery
Research News and Information
Definition of 'Parkinson Disease'A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75) |
Sunday, November 22, 2009
Pathologic findings in retinal pigment epithelial cell implantation for Parkinson disease.
31 Aug 2009 
BACKGROUND: Attempts at cell-based dopamine replacement therapy in Parkinson disease (PD) have included surgical implantation of adrenal medullary, fetal mesencephalic, and cultured human mesencephalic tissue grafts. Trials involving putamenal ... Read more...
[Management of Parkinson's disease in 2009]
24 Aug 2009 The cause of Parkinson's disease remains unknown and no cure or prevention exists so far. Levodopa remains by far the most potent symptomatic therapy, but induces side-effects such as motor fluctuations and abnormal movements, which can somewhat be ... Read more...
Deep brain stimulation for Parkinson's disease: Australian referral guidelines.
30 Jul 2009 The advent of deep brain stimulation (DBS) has been an important advance in the treatment of Parkinson's disease (PD). DBS may be employed in the management of medication-refractory tremor or treatment-related motor complications, and may benefit ... Read more...
Latest indexed articles for 'Parkinson Disease - Surgery'
These are the very latest articles for this heading:
- Neuroscience. Fetal cells again?
14 Oct 2009 - Pathologic findings in retinal pigment epithelial cell implantation for Parkinson disease. 31 Aug 2009
- Does subthalamotomy have a place in the treatment of Parkinson's disease? 30 Aug 2009
- [Management of Parkinson's disease in 2009] 24 Aug 2009
- Deep brain stimulation for Parkinson's disease: Australian referral guidelines. 30 Jul 2009
- Surgical treatment of movement disorders. 30 Jul 2009
- Movement disorders. Preface. 30 Jul 2009
- Cells therapy for Parkinson's disease--so close and so far away. 28 Jul 2009
- Long-term superiority of subthalamic nucleus stimulation over pallidotomy in Parkinson disease. 12 Jul 2009
- Dopamine dysregulation syndrome, impulse control disorders and punding after deep brain stimulation surgery for Parkinson's disease. 21 Jun 2009
- Assessing the microlesion effect of subthalamic deep brain stimulation surgery with FDG PET. 30 May 2009
- Anaesthesia and Parkinson's disease: how to manage with new therapies? 30 May 2009
- Improvement of tics after subthalamic nucleus deep brain stimulation. 17 May 2009
- Ethical challenges in cell-based interventions for neurological conditions: some lessons to be learnt from clinical transplantation trials in patients with Parkinson's disease. 29 Apr 2009
- Priming for L-DOPA-induced abnormal involuntary movements increases the severity of amphetamine-induced dyskinesia in grafted rats. 20 Apr 2009
- Efficient production of mesencephalic dopamine neurons by Lmx1a expression in embryonic stem cells.
19 Apr 2009 - A high resolution and high contrast MRI for differentiation of subcortical structures for DBS targeting: the Fast Gray Matter Acquisition T1 Inversion Recovery (FGATIR). 8 Apr 2009
- Amphetamine-induced abnormal movements occur independently of both transplant- and host-derived serotonin innervation following neural grafting in a rat model of Parkinson's disease. 6 Apr 2009
- Deep brain stimulation for Parkinson's disease. 4 Apr 2009
- Cellular xenotransplantation. 30 Mar 2009
See a longer list of these articles.
Technical information about 'Parkinson Disease'
Definition: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
Descriptor UI: D010300
Alternative terms: Parkinson Disease; Idiopathic Parkinson's Disease; Lewy Body Parkinson Disease; Lewy Body Parkinson's Disease; Primary Parkinsonism; Parkinsonism, Primary; Parkinson Disease, Idiopathic; Parkinson's Disease; Parkinson's Disease, Idiopathic; Parkinson's Disease, Lewy Body; Idiopathic Parkinson Disease; Paralysis Agitans;
Related Mesh Headings: Lewy Bodies;
Allowable Qualifiers: blood; cerebrospinal fluid; classification; complications; congenital; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; urine; veterinary; ultrasonography; virology;
Tree Number: C10.228.140.079.862.500; C10.228.662.600.400; C10.574.812;
History Note: 1979(1963)
Technical Notes: drug ther: consider also ANTIPARKINSON AGENTS; /chem ind = PARKINSON DISEASE, SECONDARY/chem ind