Paroxetine - Pharmacology
Research News and Information

Saturday, November 21, 2009

Antidepressant medication use during breastfeeding.

30 Aug 2009 We performed an electronic search by using MEDLINE, PreMEDLINE, Current Contents, Biological Abstracts, and PsycINFO from June 2002 to December 2008 using the following terms: "antidepressant drugs", "antidepressive agents", "human milk", ... Read more...

Role of nitric oxide in obsessive-compulsive behavior and its involvement in the anti-compulsive effect of paroxetine in mice.

3 Jul 2009 In view of the reports that nitric oxide modulates the neurotransmitters implicated in obsessive-compulsive disorder, patients with obsessive-compulsive disorder exhibit higher plasma nitrate levels, and drugs useful in obsessive-compulsive disorder ... Read more...

Delirium in a patient with toxic flecainide plasma concentrations: the role of a pharmacokinetic drug interaction with paroxetine.

14 Jun 2009 OBJECTIVE: To describe a case of flecainide-induced delirium associated with a pharmacokinetic drug interaction with paroxetine. CASE SUMMARY: A 69-year-old white female presented to the emergency department with a history of confusion and paranoia ... Read more...

Latest indexed articles for 'Paroxetine - Pharmacology'

These are the very latest articles for this heading:

• Antidepressant medication use during breastfeeding. 30 Aug 2009
• Role of nitric oxide in obsessive-compulsive behavior and its involvement in the anti-compulsive effect of paroxetine in mice. 3 Jul 2009
• Lessons continue: serotonin toxicity. 29 Jun 2009
• Delirium in a patient with toxic flecainide plasma concentrations: the role of a pharmacokinetic drug interaction with paroxetine. 14 Jun 2009
• Antidepressant-like effects of paroxetine are produced by lower doses than those which produce nausea. 25 May 2009
• Antidepressants inhibit P2X4 receptor function: a possible involvement in neuropathic pain relief. 21 Apr 2009
• 5-HT2A gene variants influence specific and different aspects of antidepressant response in Japanese and Italian mood disorder patients. 8 Apr 2009
• Inhibitory effect of selective serotonin reuptake inhibitors on the vesicular monoamine transporter 2. 16 Mar 2009
• Clavulanic acid stimulates sexual behaviour in male rats. 9 Mar 2009
• Intracerebroventricular infusion of cytosine-arabinoside causes prepulse inhibition disruption. 2 Mar 2009
• Evaluation of risk factors for elevated tricyclic antidepressant plasma concentrations. 27 Feb 2009
• Effects of acute alcohol intoxication and paroxetine on aggression in men. 10 Jan 2009
• Methylphenidate restores link between stop-signal sensory impact and successful stopping in adults with attention-deficit/hyperactivity disorder. 19 Dec 2008
• Selective serotonin reuptake inhibitors modify physiological gastrointestinal motor activities via 5-HT2c receptor and acyl ghrelin. 3 Dec 2008
• The effects of desvenlafaxine and paroxetine on the pharmacokinetics of the cytochrome P450 2D6 substrate desipramine in healthy adults. 9 Nov 2008
• Effect of desvenlafaxine on the cytochrome P450 2D6 enzyme system. 30 Oct 2008
• Effect of the selective serotonin reuptake inhibitor paroxetine on platelet function is modified by a SLC6A4 serotonin transporter polymorphism. 16 Oct 2008
• What is the effect of selective serotonin reuptake inhibitors on temperament and character in patients with fibromyalgia? 15 Oct 2008
• The alpha 2A-adrenergic receptor gene polymorphism modifies antidepressant responses to milnacipran. 29 Sep 2008
• Can in vitro metabolism-dependent covalent binding data in liver microsomes distinguish hepatotoxic from nonhepatotoxic drugs? An analysis of 18 drugs with consideration of intrinsic clearance and daily dose. 7 Aug 2008

See a longer list of these articles.

Technical information about 'Paroxetine'

Definition: A serotonin uptake inhibitor that is effective in the treatment of depression.

Chemical name: Piperidine, 3-((1,3-benzodioxol-5-yloxy)methyl)-4-(4-fluorophenyl)-, (3S-trans)-

Registry Number: 61869-08-7

Descriptor UI: D017374

Alternative terms: Paroxetine; Seroxat; FG-7051; Aropax; BRL-29060; BRL 29060; BRL29060; Paroxetine, trans-(+)-Isomer; Paroxetine Hydrochloride; Hydrochloride, Paroxetine; Paroxetine Hydrochloride, Hemihydrate; Hemihydrate Paroxetine Hydrochloride; Hydrochloride, Hemihydrate Paroxetine; Paroxetine Maleate; Maleate, Paroxetine; Paroxetine, cis-(+)-Isomer; Paroxetine, cis-(-)-Isomer; Paxil; Paroxetine Acetate; Acetate, Paroxetine;

Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Pharmacological Action: Serotonin Uptake Inhibitors; Antidepressive Agents, Second-Generation;

Tree Number: D03.383.621.600;

Online Note: use PAROXETINE (NM) to search PAROXETINE 1980-92

History Note: 93; was PAROXETINE (NM) 1978-92